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Browse our anti-IRF4 (IRF4) Antibodies

Full name:
anti-Interferon Regulatory Factor 4 Antibodies (IRF4)
On are 137 Interferon Regulatory Factor 4 (IRF4) Antibodies from 27 different suppliers available. Additionally we are shipping IRF4 Proteins (12) and IRF4 Kits (6) and many more products for this protein. A total of 166 IRF4 products are currently listed.
AI385587, IRF-4, irf4, LSIRF, MUM1, NF-EM5, si:ch73-170d1.2, Spip
list all antibodies Gene Name GeneID UniProt
IRF4 3662 Q15306
IRF4 16364 Q64287
IRF4 291100  

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anti-Human IRF4 Antibodies:

anti-Mouse (Murine) IRF4 Antibodies:

anti-Rat (Rattus) IRF4 Antibodies:

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Top referenced anti-IRF4 Antibodies

  1. Human Polyclonal IRF4 Primary Antibody for FACS, WB - ABIN656568 : Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. in Molecular human reproduction 2010 (PubMed)
    Show all 3 references for ABIN656568

  2. Human Monoclonal IRF4 Primary Antibody for IHC (fro), IHC (p) - ABIN115258 : Gaidano, Carbone: MUM1: a step ahead toward the understanding of lymphoma histogenesis. in Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000 (PubMed)
    Show all 2 references for ABIN115258

  3. Human Polyclonal IRF4 Primary Antibody for ELISA, WB - ABIN1533903 : Grossman, Mittrücker, Nicholl, Suzuki, Chung, Antonio, Suggs, Sutherland, Siderovski, Mak: Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. in Genomics 1997 (PubMed)
    Show all 2 references for ABIN1533903

  4. Human Polyclonal IRF4 Primary Antibody for EIA, FACS - ABIN952951 : Staudt, Bothur, Klein, Lingnau, Reuter, Grebe, Gerlitzki, Hoffmann, Ulges, Taube, Dehzad, Becker, Stassen, Steinborn, Lohoff, Schild, Schmitt, Bopp: Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. in Immunity 2010 (PubMed)
    Show all 2 references for ABIN952951

  5. Human Polyclonal IRF4 Primary Antibody for EIA, WB - ABIN783470 : Malmgaard: Induction and regulation of IFNs during viral infections. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 (PubMed)

  6. Chicken Polyclonal IRF4 Primary Antibody for IHC, WB - ABIN2780428 : Lehtonen, Veckman, Nikula, Lahesmaa, Kinnunen, Matikainen, Julkunen: Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  7. Chicken Polyclonal IRF4 Primary Antibody for WB - ABIN2780429 : Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. in PLoS genetics 2008 (PubMed)

More Antibodies against IRF4 Interaction Partners

Human Interferon Regulatory Factor 4 (IRF4) interaction partners

  1. The anti-PEL effects of IMiDs involved cereblon-dependent suppression of IRF4 and rapid degradation of IKZF1

  2. IRF4 single nucleotide polymorphism is predictive factor of melanoma subtypes.

  3. Role of IRF4 rs12203592 in pathway-specific risk for melanoma development. Hypothesize that IRF4 rs12203592 could underlie in part the bimodal age distribution reported for melanoma and linked to the divergent pathways

  4. These results indicate that the KDM3A (show KDM3A Antibodies)-KLF2 (show KLF2 Antibodies)-IRF4 pathway plays an essential role in multiple myeloma cell survival and homing to the bone marrow, and therefore represents a therapeutic target.

  5. FOXO1 (show FOXO1 Antibodies) and PR are required for the regulation of IRF4, a novel transcriptional regulator of decidualization in human endometrial stromal cells.

  6. inhibition of IRF4 translated into downregulation of c-Myc (show MYC Antibodies), caspase-10 (show CASP10 Antibodies) and cFlip (show CFLAR Antibodies), relevant IRF4-downstream effectors

  7. Overall, our data strongly suggest that IRF4, MC1R (show MSHR Antibodies) and TYR (show TYR Antibodies) genes likely have pleiotropic effects, a combination of pigmentation and oncogenic functions, resulting in an increased risk of actinic keratosis.

  8. collagen I induces TNF- alpha (show TNF Antibodies) production, which is crucial for the activation and function of DCs, through down-regulation of IRF4, and implicates the importance in development of anti- TNF-alpha (show TNF Antibodies) therapeutics for several inflammatory diseases.

  9. Allele-specific transcriptional regulation of IRF4 in melanocytes is mediated by chromatin looping of the intronic rs12203592 enhancer to the IRF4 promoter

  10. IRF4 is deregulated in B cells from common variable immunodeficiency patients, contributing to the observed aberrant expression of activation-induced deaminase (show AICDA Antibodies) in these patients.

Mouse (Murine) Interferon Regulatory Factor 4 (IRF4) interaction partners

  1. data reveal that CCR7 (show CCR7 Antibodies) plays multifaceted roles in regulating collecting vessel permeability and fibrosis, with one of the key players being IRF4-dependent DCs.

  2. IRF4 was essential for the survival of plasma cells.

  3. a critical role for IRF4 in regulating protective anti-viral CD8 (show CD8A Antibodies)+ T cell responses by ensuring a balanced ratio of T-bet to Eomes (show EOMES Antibodies)

  4. variation in IRF4 or IRF8 (show IRF8 Antibodies) levels resulting from genetic polymorphisms or environmental cues will govern tissue dendritic cells numbers and regulate the magnitude of their functional responses.

  5. DC dysfunction in lupus-prone mice relies on both IRF4-dependent and IRF4-independent pathways

  6. APN (show ANPEP Antibodies) can help to reduce periodontitis-related bone loss, modulate JMJD3 (show Kdm6b Antibodies) and IRF4 expression, and macrophage infiltration.

  7. Data indicate that interferon (show IFNA Antibodies) regulatory factors IRF4 and IRF8 (show IRF8 Antibodies) control distinct activated B cell states.

  8. this study determined the small angle x-ray scattering solution structure of full-length IRF4, which, together with circular dichroism studies, suggests that the linker region is not extended but folds into a domain structure

  9. data support a novel and critical role for Nr4a1 (show NR4A1 Antibodies) in the regulation of CD8 (show CD8A Antibodies)(+) T cell expansion and effector function through transcriptional repression of Irf4.

  10. inhibition of IRF4 attenuates acute liver allograft rejection in mice, and this is associated with promoted M2 macrophage differentiation.

IRF4 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6\;14)(p25\;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with IRF4

  • interferon regulatory factor 4 (IRF4) antibody
  • Interferon regulatory factor 4 (irf4) antibody
  • interferon regulatory factor 4 (LOC100223845) antibody
  • interferon regulatory factor 4 (Irf4) antibody
  • interferon regulatory factor 4a (irf4a) antibody
  • melanoma associated antigen (mutated) 1 (MUM1) antibody
  • AI385587 antibody
  • IRF-4 antibody
  • irf4 antibody
  • LSIRF antibody
  • MUM1 antibody
  • NF-EM5 antibody
  • si:ch73-170d1.2 antibody
  • Spip antibody

Protein level used designations for IRF4

interferon regulatory factor 4 , Interferon regulatory factor 4 , lymphocyte-specific interferon regulatory factor , multiple myeloma oncogene 1 , NF-EM5 , PU.1 interaction partner , Sfpi1/PU.1 interaction partner , transcriptional activator PIP , irf4 , MUM-1 , PWWP domain-containing protein MUM1 , mutated melanoma-associated antigen 1

462386 Pan troglodytes
722883 Macaca mulatta
100194953 Salmo salar
100223845 Taeniopygia guttata
100590106 Nomascus leucogenys
3662 Homo sapiens
374179 Gallus gallus
100144625 Sus scrofa
16364 Mus musculus
291100 Rattus norvegicus
100002070 Danio rerio
612320 Canis lupus familiaris
513471 Bos taurus
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