anti-Human ITK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ITK Antibody (supplied by: Log in to see )

Antigen
IL2-Inducible T-Cell Kinase (ITK) Antibodies
  • Emt
  • Tcsk
  • Tsk
  • EMT
  • LPFS1
  • LYK
  • PSCTK2
  • IL2 inducible T cell kinase
  • IL2-inducible T-cell kinase
  • Itk
  • ITK
Epitope
AA 596-607
24
17
14
10
9
8
7
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
111
26
21
4
2
1
1
1
Host
Goat
65
31
26
Clonality
Polyclonal
Conjugate
This ITK antibody is un-conjugated
7
7
6
6
6
6
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
106
78
11
9
8
7
7
4
3
2
1
Supplier
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Catalog No. ABIN783291
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN609692 IHC (p) Goat AA 596-607 Log in to see Polyclonal
1 ABIN1736082 IHC (p) Goat AA 596-607 Log in to see Polyclonal
1 ABIN680653 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2771419 IHC (p) Goat AA 596-607 Log in to see Polyclonal

General

Antigen IL2-Inducible T-Cell Kinase (ITK) Antibodies
Epitope AA 596-607
(24), (17), (14), (10), (9), (8), (7), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(111), (26), (21), (4), (2), (1), (1), (1)
Host Goat
(65), (31), (26)
Clonality
Polyclonal
Conjugate This ITK antibody is un-conjugated
(7), (7), (6), (6), (6), (6)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(106), (78), (11), (9), (8), (7), (7), (4), (3), (2), (1)
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Product Details anti-ITK Antibody

Target Details ITK Application Details Handling Images
Specificity This antibody reacts to Interleukin 2 Tyrosine Kinase (ITK).
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide C-KERPEDRPAFSR from positions 596-607 of human ITK (NP_005537.3). Genename: ITK
Isotype IgG

Target Details ITK

Product Details anti-ITK Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tyrosine-Protein Kinase ITK/TSK (ITK Antibody Abstract)
Background Interleukin-2 tyrosine kinase (ITK), a BTK/TEC type tyrosine kinase, is critical for efficient signaling downstream of the T cell receptor. Itk is directly phosphorylated and activated by Lck. Subsequently, Itk activates phospholipase C-gamma1, leading to calcium mobilization and extracellular signal-regulated kinase/mitogen-activated protein kinase activation. Itk contains five domains in addition to the catalytic domain: pleckstrin homology, Tec homology which contains a proline-rich region, Src homology 3, and Src homology 2.Synonyms: EMT, Kinase EMT, LYK, T-cell-specific kinase, Tyrosine-protein kinase Lyk
Gene ID 3702
NCBI Accession NP_005537
UniProt Q08881
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-ITK Antibody Target Details ITK Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ITK Antibody Target Details ITK Application Details Images back to top
Concentration 0,5 mg/mL
Buffer Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

Images

Product Details anti-ITK Antibody Target Details ITK Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IL2-Inducible T-Cell Kinase (ITK) (AA 596-607) antibody (ABIN783291) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)