Browse our ITPR1 (ITPR1) ELISA Kits

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Inositol 1,4,5-Trisphosphate Receptor, Type 1 ELISA Kits (ITPR1)
On are 1 Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) ELISA Kits from 1 different suppliers available. Additionally we are shipping ITPR1 Antibodies (42) and ITPR1 Proteins (5) and many more products for this protein. A total of 48 ITPR1 products are currently listed.
D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, INSP3R1, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29
list all ELISA KIts Gene Name GeneID UniProt
Mouse ITPR1 ITPR1 16438 P11881
Rat ITPR1 ITPR1 25262 P29994
ITPR1 3708 Q14643

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Mouse (Murine) Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. Cone-specific gene deletion of the inositol-1,4,5-trisphosphate receptor type I (IP3R1) also significantly increased cone density in the CNG (show CNGA1 ELISA Kits)-channel-deficient mice, suggesting that IP3R1 signaling contributes to Ca(2 (show CA2 ELISA Kits)+) homeostasis and cone survival.

  2. Pathological mutations of ITPR1 (inositol 1,4,5-trisphosphate receptor, type 1) were found in seven patients from four families all localized in the IRBIT (show AHCYL1 ELISA Kits) (inositol triphosphate receptor binding protein) domain.

  3. The results suggest that IP3R1 and IP3R3 (show ITPR3 ELISA Kits) are required for extra-embryonic vascularization in the placenta, allantois, and yolk sac (show ADCY10 ELISA Kits).

  4. The results show that phosphorylations by Cdk1 (show CDK1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) enhance the activity of IP3R1, which is consistent with its maximal activity observed at the time of fertilization and the role of Ca(2 (show CA2 ELISA Kits)+) release in egg activation.

  5. data indicate that PTPalpha (show PTPRA ELISA Kits) and FAK (show PTK2 ELISA Kits), which are enriched in FAs (show FAS ELISA Kits), interact with IP3R1 at adjacent ER sites to spatially sequester IL-1 (show IL1A ELISA Kits)-induced Ca(2 (show CA2 ELISA Kits)+) signalling

  6. IGF-1 (show IGF1 ELISA Kits) strengthens the interaction between NCS-1 (show NCS1 ELISA Kits) and IP3R in the process of regulation of nuclear Ca2 (show CA2 ELISA Kits)+ signaling in cardiomyocytes.

  7. Car8 (show CA8 ELISA Kits) regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

  8. cGMP/protein kinase (show CDK7 ELISA Kits) G signaling suppresses Itpr1 phosphorylation and promotes endoplasmic reticulum stress in photoreceptors of Cnga3 (show CNGA3 ELISA Kits)-deficient mice.

  9. Association of SLAT (show DEF6 ELISA Kits) with IP receptor 1 promotes Ca(2 (show CA2 ELISA Kits)) signaling in T cells.

  10. IP3R-mediated Ca2 (show CA2 ELISA Kits)+ signaling reinforces Tcf-1 (show HNF1A ELISA Kits) activity to both ensure normal development and to prevent thymocyte neoplasia.

Human Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. Data suggest that ADRB2 (beta2 adrenergic receptor (show ADRB2 ELISA Kits)) activation (as illustrated by epinephrine and nor epinephrine) leads to robust calcium ion mobilization from intracellular stores in endoplasmic reticulum via activation of phosphoinositide phospholipase C (PLC (show PIPLC ELISA Kits)) and opening of inositol trisphosphate receptor (IP3R).

  2. Data indicate that unlike ryanodine receptor RyRs, inositol 145-trisphosphate receptor IP3Rs are present and continually functional at early stages of cardiomyocyte differentiation.

  3. ITPR1 is the SCA15 causative gene.

  4. results demonstrate biallelic and monoallelic ITPR1 mutations as the underlying genetic defects for Gillespie syndrome, further extending the spectrum of ITPR1-related diseases

  5. Dominant De Novo ITPR1 Mutations Cause Gillespie Syndrome.

  6. Studies indicate that four IP3-binding sites within the tetrameric inositol 1,4,5-trisphosphate receptors (IP3Rs) must bind inositol 145-trisphosphate (IP3) before the channel can open for intracellular Ca2 (show CA2 ELISA Kits)+ signals.

  7. Data show that inositol 145-trisphosphate receptor type 1 (IP3R1) -with a single inositol 145-trisphosphate (IP3) binding-deficient subunit lack activity.

  8. SNPs in ITPR1 and CNTN4 (show CNTN4 ELISA Kits) are involved in the regulation of serum uric acid concentrations in Mexican Americans

  9. concluded that the HERPUD1 (show HERPUD1 ELISA Kits)-mediated cytoprotective effect against oxidative stress depends on the ITPR and Ca(2 (show CA2 ELISA Kits)+) transfer from the endoplasmic reticulum to mitochondria

  10. Studies indicate that the ryanodine receptors (RyRs: RyR1 (show RYR1 ELISA Kits), RyR2 (show RYR2 ELISA Kits), RyR3 (show RYR3 ELISA Kits)) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1, IP3R2 (show ITPR2 ELISA Kits), IP3R3 (show ITPR3 ELISA Kits)) are the major Ca(2 (show CA2 ELISA Kits)+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).

Cow (Bovine) Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) interaction partners

  1. STIM1 (show STIM1 ELISA Kits) and STIM2 (show Stim2 ELISA Kits) are expressed in bovine aortic endothelial cells and they both interact with IP3R-1.

  2. we propose a model in which the partial unfolding of the suppressor domain by apo (show C9orf3 ELISA Kits)-CaM (show KRIT1 ELISA Kits) and the stepwise binding of the N lobe (show LTF ELISA Kits) of CaM (show KRIT1 ELISA Kits) to the suppressor domain are important elements of calcium/CaM (show KRIT1 ELISA Kits) inhibition of IP(3)R

  3. structural mapping of the amino acid sequences to several functional domains is deduced within the structure of the InsP3R1 tetramer

  4. the InsP3R/Ca2 (show CA2 ELISA Kits)+ channel is regulated by chromogranin B (show CHGB ELISA Kits)

  5. the redox potential and Ca(2 (show CA2 ELISA Kits)+) can regulate IP(3)R through totally different mechanisms: Ca(2 (show CA2 ELISA Kits)+) by the indirect effect and the redox potential by direct action causing conformational changes

ITPR1 Antigen Profile

Antigen Summary

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Alternative names and synonyms associated with ITPR1

  • inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) Elisa Kit
  • inositol 1,4,5-trisphosphate receptor 1 (Itpr1) Elisa Kit
  • inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1) Elisa Kit
  • D6Pas2 Elisa Kit
  • ENSMUSG00000072853 Elisa Kit
  • Gm10429 Elisa Kit
  • I145TR Elisa Kit
  • InsP3R Elisa Kit
  • INSP3R1 Elisa Kit
  • IP3R Elisa Kit
  • IP3R1 Elisa Kit
  • Itpr-1 Elisa Kit
  • opt Elisa Kit
  • P400 Elisa Kit
  • Pcp-1 Elisa Kit
  • Pcp1 Elisa Kit
  • SCA15 Elisa Kit
  • SCA16 Elisa Kit
  • SCA29 Elisa Kit

Protein level used designations for ITPR1

inositol 1,4,5-triphosphate receptor, type 1 , type I inositol triphosphate receptor , IP3 receptor , IP3R 1 , InsP3R type I , InsP>3

395412 Gallus gallus
476548 Canis lupus familiaris
100052808 Equus caballus
16438 Mus musculus
25262 Rattus norvegicus
3708 Homo sapiens
317697 Bos taurus
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