Browse our anti-LAT (LAT) Antibodies

Full name:
anti-Linker For Activation of T Cells Antibodies (LAT)
On www.antibodies-online.com are 270 Linker For Activation of T Cells (LAT) Antibodies from 26 different suppliers available. Additionally we are shipping LAT Kits (27) and LAT Proteins (12) and many more products for this protein. A total of 322 LAT products are currently listed.
Synonyms:
lat, LAT1, pp36

Most Popular Reactivities for anti-LAT (LAT) Antibodies

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anti-Mouse (Murine) LAT Antibodies:

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Top referenced anti-LAT Antibodies

  1. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967609 : Cho, Velikovsky, Swaminathan, Houtman, Samelson, Mariuzza: Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. in The EMBO journal 2004 (PubMed)
    Show all 6 references for 967609

  2. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177079 : Janssen, Zhang: Adaptor proteins in lymphocyte activation. in Current opinion in immunology 2003 (PubMed)
    Show all 6 references for 1177079

  3. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967594 : Lin, Weiss: Identification of the minimal tyrosine residues required for linker for activation of T cell function. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for 967594

  4. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177080 : Paz, Wang, Clarke, Lu, Stokoe, Abo: Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells. in The Biochemical journal 2001 (PubMed)
    Show all 5 references for 1177080

  5. Human Monoclonal LAT Primary Antibody for WB - ABIN393665 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 5 references for 393665

  6. Mouse (Murine) Monoclonal LAT Primary Antibody for IF, IP - ABIN238425 : Yamasaki, Ishikawa, Sakuma, Kanagawa, Cheng, Malissen, Saito: LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival. in Molecular and cellular biology 2007 (PubMed)
    Show all 5 references for 238425

  7. Human Polyclonal LAT Primary Antibody for ELISA, WB - ABIN1533125 : Zhang, Sloan-Lancaster, Kitchen, Trible, Samelson: LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. in Cell 1998 (PubMed)
    Show all 2 references for 1533125

  8. Human Polyclonal LAT Primary Antibody for ELISA, WB - ABIN250250 : Finco, Kadlecek, Zhang, Samelson, Weiss: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. in Immunity 1998 (PubMed)

More Antibodies against LAT Interaction Partners

Human Linker For Activation of T Cells (LAT) interaction partners

  1. LAT (show ORC3 Antibodies) and SLP-76 (show LCP2 Antibodies) are randomly dispersed throughout the clusters that form upon T cell receptor engagement.

  2. this study shows that inherited LAT (show ORC3 Antibodies) deficiency should be considered in patients with combined immunodeficiency with T-cell abnormalities

  3. This is the first report of a LAT (show ORC3 Antibodies)-related disease in humans, manifesting by a progressive combined immune deficiency with severe autoimmune disease.

  4. Data show that LAT1 plays an important role in regulating the uptake of essential amino acids such as leucine into endometrial cancer cells. Increased ability of BCH (show CHN2 Antibodies) compared to LAT1 shRNA at inhibiting Ishikawa spheroid area suggests that other LAT (show ORC3 Antibodies) family members may also contribute to cell growth.

  5. Data indicate that the T cell-specific adaptor protein (TSAd (show SH2D2A Antibodies)) SH2 domain interacts with CD6 antigen (show CD6 Antibodies) and linker for activation of T cells protein (LAT (show ORC3 Antibodies)) phosphotyrosine (pTyr) peptides.

  6. High expression of LAT1 and ASCT2 (show SLC1A5 Antibodies) correlates with metastasis and invasion in esophageal squamous cell carcinoma.

  7. IFT20 (show IFT20 Antibodies) is required for the delivery of the intracellular pool of LAT (show ORC3 Antibodies) to the immune synapse in naive primary T lymphocytes.

  8. Data show that the palmitoylation mutation of linker for activation of T cells (LAT)attenuated the signal transduction induced by glycosylphosphatidylinositol-anchored CD59 antigen (show CD59 Antibodies) in T cells.

  9. HSV-1-encoded Us3 protein interrupted TCR signaling and interleukin-2 (show IL2 Antibodies) production by inactivation of the linker for activation of T cells.

  10. Patients with severe aplastic anemia had increased levels of LAT (show ORC3 Antibodies) and disturbed Th1 (show TH1L Antibodies)-Th2 balance.

Mouse (Murine) Linker For Activation of T Cells (LAT) interaction partners

  1. this study shows that the site-specific delivery of linker for activation of T cells (LAT) in asthmatic mouse model

  2. IFT20 (show IFT20 Antibodies) is required for the delivery of the intracellular pool of LAT to the immune synapse in naive primary T lymphocytes.

  3. miR (show MLXIP Antibodies)-155 regulates the delicate balance between PAK1 (show PAK1 Antibodies)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

  4. provide evidence that CD28 (show CD28 Antibodies) and the TCR complex regulate NF-kappaB (show NFKB1 Antibodies) via different signaling modules of GRB-2 (show GRB2 Antibodies)/VAV1 (show VAV1 Antibodies) and LAT/ADAP (show APP Antibodies) pathways respectively.

  5. The result indicate that LAT-PLCg1 (show PLCG1 Antibodies) interaction is important for controlling IL-6 (show IL6 Antibodies) production by T cells and demonstrate a critical role of IL-6 (show IL6 Antibodies) in the development of the lymphoproliferative syndrome.

  6. low level of LAT-PLC-gamma1 (show PLCG1 Antibodies) interaction was associated with Th2 polarized differentiation, and this may contribute to the etiology of asthma.

  7. These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT and PLCgamma1 (show PLCG1 Antibodies) in Dow2-induced anergic T cells. The novel CD3 (show CD3E Antibodies)-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression

  8. Sos1 (show SOS1 Antibodies) has distinct roles in acting as a scaffold to oligomerize the adaptor protein LAT, and in guanine nucleotide exchange activity

  9. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Antibodies)-Lat-SLP-76 (show LCP2 Antibodies) network and thus should provide cues for future functional experiments.

  10. Data suggest that transmembrane adaptor protein LAT-PLCgamma1 (Phospholipase C gamma 1 (show PLCG1 Antibodies)) signaling may function differently in various subsets of gammadelta T cells.

LAT Antigen Profile

Antigen Summary

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with LAT

  • linker for activation of T cells (LAT) antibody
  • linker for activation of T cells (lat) antibody
  • linker for activation of T cells (Lat) antibody
  • lat antibody
  • LAT1 antibody
  • pp36 antibody

Protein level used designations for LAT

linker for activation of T cells , 36 kDa phospho-tyrosine adapter protein , 36 kDa phospho-tyrosine adaptor protein , linker for activation of T cells, transmembrane adaptor , linker for activation of T-cells family member 1 , p36-38 , pp36 , linker protein

GENE ID SPECIES
704656 Macaca mulatta
743295 Pan troglodytes
100233211 Danio rerio
27040 Homo sapiens
81511 Rattus norvegicus
16797 Mus musculus
514735 Bos taurus
607947 Canis lupus familiaris
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