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Browse our anti-LAT (LAT) Antibodies

Full name:
anti-Linker For Activation of T Cells Antibodies (LAT)
On www.antibodies-online.com are 192 Linker For Activation of T Cells (LAT) Antibodies from 25 different suppliers available. Additionally we are shipping LAT Kits (19) and LAT Proteins (12) and many more products for this protein. A total of 234 LAT products are currently listed.
Synonyms:
lat, LAT1, pp36

All available anti-LAT Antibodies

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Top referenced anti-LAT Antibodies

  1. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177079 : Cho, Velikovsky, Swaminathan, Houtman, Samelson, Mariuzza: Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. in The EMBO journal 2004 (PubMed)
    Show all 6 references for ABIN1177079

  2. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967609 : Janssen, Zhang: Adaptor proteins in lymphocyte activation. in Current opinion in immunology 2003 (PubMed)
    Show all 6 references for ABIN967609

  3. Mouse (Murine) Monoclonal LAT Primary Antibody for IF, IP - ABIN238425 : Yamasaki, Ishikawa, Sakuma, Kanagawa, Cheng, Malissen, Saito: LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival. in Molecular and cellular biology 2007 (PubMed)
    Show all 5 references for ABIN238425

  4. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177080 : Lin, Weiss: Identification of the minimal tyrosine residues required for linker for activation of T cell function. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN1177080

  5. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967594 : Paz, Wang, Clarke, Lu, Stokoe, Abo: Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells. in The Biochemical journal 2001 (PubMed)
    Show all 5 references for ABIN967594

  6. Mouse (Murine) Monoclonal LAT Primary Antibody for ICC, IP - ABIN94420 : Tolar, T?mová, Dráber: New monoclonal antibodies recognizing the adaptor protein LAT. in Folia biologica 2001 (PubMed)
    Show all 5 references for ABIN94420

  7. Human Monoclonal LAT Primary Antibody for WB - ABIN393665 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 5 references for ABIN393665

  8. Human Monoclonal LAT Primary Antibody for FACS, IP - ABIN302069 : Simeoni, Smida, Posevitz, Schraven, Lindquist: Right time, right place: the organization of membrane proximal signaling. in Seminars in immunology 2004 (PubMed)
    Show all 5 references for ABIN302069

  9. Human Polyclonal LAT Primary Antibody for ELISA, WB - ABIN1533125 : Zhang, Sloan-Lancaster, Kitchen, Trible, Samelson: LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. in Cell 1998 (PubMed)
    Show all 2 references for ABIN1533125

  10. Human Polyclonal LAT Primary Antibody for EIA, WB - ABIN782942 : Finco, Kadlecek, Zhang, Samelson, Weiss: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. in Immunity 1998 (PubMed)

More Antibodies against LAT Interaction Partners

Human Linker For Activation of T Cells (LAT) interaction partners

  1. IFT20 (show IFT20 Antibodies) is required for the delivery of the intracellular pool of LAT (show ORC3 Antibodies) to the immune synapse in naive primary T lymphocytes.

  2. Data show that the palmitoylation mutation of linker for activation of T cells (LAT)attenuated the signal transduction induced by glycosylphosphatidylinositol-anchored CD59 antigen (show CD59 Antibodies) in T cells.

  3. HSV-1-encoded Us3 protein interrupted TCR signaling and interleukin-2 (show IL2 Antibodies) production by inactivation of the linker for activation of T cells.

  4. Patients with severe aplastic anemia had increased levels of LAT (show ORC3 Antibodies) and disturbed Th1 (show TH1L Antibodies)-Th2 balance.

  5. LAT (show ORC3 Antibodies) is a modulator of CD3zeta (show CD247 Antibodies) and ZAP-70 (show ZAP70 Antibodies) tyrosine phosphorylation.

  6. mutation of palmitoylation site of LAT (show ORC3 Antibodies)-EGFP attenuated the signal transduction of CD59 (show CD59 Antibodies) in T cells

  7. findings show that L-type amino acid transporter 1 (show SLC7A5 Antibodies) is a major transporter for essential amino acids into activated human T cells

  8. Histone hypoacetylation on LAT (show ORC3 Antibodies) promoter could inhibit LAT (show ORC3 Antibodies) expression and enhanced Th2 differentiation, while trichostatin A, a histone deacetylase (show HDAC1 Antibodies) inhibitor, promoted LAT (show ORC3 Antibodies) expression and inhibited Th2 cytokine production

  9. LAT (show ORC3 Antibodies) is required to maintain calcium homeostasis in T cells.

  10. A novel function and mechanism of TRAF6 (show TRAF6 Antibodies) action in the T cell receptor(TCR)-LAT (show ORC3 Antibodies) signaling pathway indicates that LAT (show ORC3 Antibodies) also plays an adapter role in TCR/CD28 (show CD28 Antibodies)-induced activation of TRAF6 (show TRAF6 Antibodies).

Mouse (Murine) Linker For Activation of T Cells (LAT) interaction partners

  1. IFT20 (show IFT20 Antibodies) is required for the delivery of the intracellular pool of LAT to the immune synapse in naive primary T lymphocytes.

  2. miR (show MLXIP Antibodies)-155 regulates the delicate balance between PAK1 (show PAK1 Antibodies)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

  3. provide evidence that CD28 (show CD28 Antibodies) and the TCR complex regulate NF-kappaB (show NFKB1 Antibodies) via different signaling modules of GRB-2 (show GRB2 Antibodies)/VAV1 (show VAV1 Antibodies) and LAT/ADAP (show APP Antibodies) pathways respectively.

  4. The result indicate that LAT-PLCg1 (show PLCG1 Antibodies) interaction is important for controlling IL-6 (show IL6 Antibodies) production by T cells and demonstrate a critical role of IL-6 (show IL6 Antibodies) in the development of the lymphoproliferative syndrome.

  5. low level of LAT-PLC-gamma1 (show PLCG1 Antibodies) interaction was associated with Th2 polarized differentiation, and this may contribute to the etiology of asthma.

  6. These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT and PLCgamma1 (show PLCG1 Antibodies) in Dow2-induced anergic T cells. The novel CD3 (show CD3E Antibodies)-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression

  7. Sos1 (show SOS1 Antibodies) has distinct roles in acting as a scaffold to oligomerize the adaptor protein LAT, and in guanine nucleotide exchange activity

  8. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Antibodies)-Lat-SLP-76 (show LCP2 Antibodies) network and thus should provide cues for future functional experiments.

  9. Data suggest that transmembrane adaptor protein LAT-PLCgamma1 (Phospholipase C gamma 1 (show PLCG1 Antibodies)) signaling may function differently in various subsets of gammadelta T cells.

  10. chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI (show FCER1A Antibodies), tetraspanin CD9 (show CD9 Antibodies), transmembrane adaptor proteins NTAL (show LAT2 Antibodies) and LAT, and cytoskeleton-regulatory proteins of the ERM (show ETV5 Antibodies) family

LAT Antigen Profile

Antigen Summary

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with LAT

  • linker for activation of T cells (LAT) antibody
  • linker for activation of T cells (lat) antibody
  • linker for activation of T cells (Lat) antibody
  • lat antibody
  • LAT1 antibody
  • pp36 antibody

Protein level used designations for LAT

linker for activation of T cells , 36 kDa phospho-tyrosine adapter protein , 36 kDa phospho-tyrosine adaptor protein , linker for activation of T cells, transmembrane adaptor , linker for activation of T-cells family member 1 , p36-38 , pp36 , linker protein

GENE ID SPECIES
704656 Macaca mulatta
743295 Pan troglodytes
100233211 Danio rerio
27040 Homo sapiens
81511 Rattus norvegicus
16797 Mus musculus
514735 Bos taurus
607947 Canis lupus familiaris
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