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|Antigen||Luteinizing Hormone beta Polypeptide (LHB) Antibodies|
|Conjugate||This LHB antibody is un-conjugated Alternatives|
Immunoradiometric Assay (IRMA), Radioimmunoassay (RIA), ELISA
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Product Details anti-LHB AntibodyTarget Details LHB Application Details Handling Images
|Specificity||This antibody recognises human luteinizing hormone, a gonadotrophic hormone found in the anterior lobe of the pituitary gland. TSH: 20 % hCG: 6 % FSH: 6 % Prolactin: 0.1 % hPL: 0.1 %|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Highly purified human pituitary luteinizing hormone.|
Target Details LHBProduct Details anti-LHB Antibody Application Details Handling Images back to top
|Alternative Name||Luteinizing Hormone beta (LSH-Beta) (LHB Antibody Abstract)|
|Background||Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.Synonyms: LH|
|Pathways||Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process|
Application DetailsProduct Details anti-LHB Antibody Target Details LHB Handling Images back to top
IRMA. Radioimmunoassays: >1/50,000 initial dilution in 125I RIA overnight assay. ELISA: Has been used for coating and also as a capture antibody in a two site assay inconjunction with other monoclonal antibodies.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LHB Antibody Target Details LHB Application Details Images back to top
|Buffer||Phosphate buffered saline, pH 7.2 containing 0.09 % Sodium Azide (NaN3)|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|