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|Application / Reactivity||Human|
|Cytometry by Time of Flight (CyTOF)||2 Antibodies|
|Detection (D)||1 Antibodies|
|Dot Blot (DB)||2 Antibodies|
|ELISA (Detection)||1 Antibodies|
|Enzyme Immunoassay (EIA)||12 Antibodies|
|Flow Cytometry (FACS)||28 Antibodies|
|Immunoassay (IA)||4 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||15 Antibodies|
|Immunohistochemistry (IHC)||11 Antibodies|
|Immunohistochemistry (Acetone-fixed) (IHC (af))||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||38 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Immunoradiometric Assay (IRMA)||2 Antibodies|
|Protein Assay (PrA)||2 Antibodies|
|Radioimmunoassay (RIA)||6 Antibodies|
|Western Blotting (WB)||45 Antibodies|
|Antigen||Luteinizing Hormone beta Polypeptide (LHB) Antibodies|
|Conjugate||This LHB antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-LHB AntibodyTarget Details LHB Application Details Handling Images
This antibody stains both free and intact LH and is useful for the classification of pituitary adenomas and tumors of the pituitary.
Cellular Localization: Cytoplasmic.
|Purification||Protein A Chromatography.|
Target Details LHBProduct Details anti-LHB Antibody Application Details Handling Images back to top
|Alternative Name||Luteinizing Hormone beta (LSH-Beta) (LHB Antibody Abstract)|
|Background||Luteinizing Hormone (LH) is a tropic hormone which modulates the secretory activity of other endocrine glands. This glycoprotein hormone is produced in the anterior hypophysis of the pituitary gland. In the female an acute rise of LH the LH surge - triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids, the beta subunit vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action. and is responsible for interaction with the LH receptor.Synonyms: LH-B, LHB, LSH-beta, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta|
|Pathways||TCR Signaling, Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process|
Application DetailsProduct Details anti-LHB Antibody Target Details LHB Handling Images back to top
Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. Positive Control: Human anterior pituitary.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LHB Antibody Target Details LHB Application Details Images back to top
|Buffer||10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|