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Data show that estradiol or bisphenol A decreased expression of luteinizing hormone beta (Lhb), follicle stimulating hormone beta (Fshb (show FSHB ELISA Kits)), and intracellular adhesion molecule (show NCAM1 ELISA Kits)-5 (Icam5 (show ICAM5 ELISA Kits)) in females but only decreased expression of Icam5 (show ICAM5 ELISA Kits) in males.
WT1 (show WT1 ELISA Kits) can modulate LHbeta transcription with differential roles for the two WT1 (show WT1 ELISA Kits) variants
SCGB3A2 (show SCGB3A2 ELISA Kits) regulates FSH (show BRD2 ELISA Kits)/LH production in the anterior pituitary lobe.
This is the first conclusive evidence for the physiological importance of the activation of Gq/11 by the LH receptor (show LHCGR ELISA Kits) and for the involvement of Galphaq (show GNAQ ELISA Kits)/11 in ovulation.
GnRH (show GNRH1 ELISA Kits) stimulates AMPK (show PRKAA1 ELISA Kits), and AMPK (show PRKAA1 ELISA Kits) inhibition suppresses GnRH (show GNRH1 ELISA Kits)-stimulated LHbeta transcription.
Data suggest that highly bioactive luteinizing hormone (both alpha [Cga (show CGA ELISA Kits)] and beta [Lhb] subunits) is produced by embryo/blastocyst at time of implantation; Lhb transcripts are detected in blastocysts on day 6 after fertilization.
Data indicate that free fatty acids up-regulated luteinizing hormone beta (Lhb) mRNA expression acutely but suppressed follicle stimulating hormone beta (Fshb (show FSHB ELISA Kits)) mRNA expression.
A molecular mechanism involving Egr1 (show EGR1 ELISA Kits) as a critical integrator of complex formation on the LHbeta promoter during GnRH (show GNRH1 ELISA Kits) induction and glucocorticoid receptor (show NR3C1 ELISA Kits) repression.
FOXO1 (show FOXO1 ELISA Kits) transcription factor inhibits luteinizing hormone beta gene expression in pituitary gonadotrope cells
CBP may act as a key regulator of LH-beta expression in the gonadotroph by integrating homeostatic information with GNRH signaling.
LHbeta G1052A and LHCGR (show LHCGR ELISA Kits) G935A genes polymorphisms are associated with increased risk of polycystic ovary syndrome in Egyptian women especially in obese cases.
The Trp8Arg/Ile15Thr polymorphism within the LHB gene was not associated with endometriosis and infertility.
LH, progesterone, and TSH can stimulate aldosterone.
Data indicate a modulatory effect of luteinizing hormone beta-subunit (LHB) gene polymorphisms on hyperandrogenemia phenotype of Polycystic Ovary Syndrome (PCOS) was observed.
Both estradiol and progesterone uniquely modulate basal and GnRH-stimulated gonadotropin promoters without affecting cell growth.
Negative fetal FSH (show BRD2 ELISA Kits)/LH regulation in late pregnancy is associated with declined kisspeptin/KISS1R (show KISS1R ELISA Kits) expression in the tuberal hypothalamus.
Polymorphisms of Trp8Arg and Ile15Thr in the LH-beta subunit gene occur in infertile women.
We identified seven SNPs in the LH beta gene; one SNP in exon 3 (rs#1056917) exhibited significant difference in the allele frequency between the PCOS cases and controls
the presence of LHbeta G1502A and ERbeta (show ESR2 ELISA Kits) G+1730A polymorphisms is associated with infertility and endometriosis associated infertility.When two polymorphisms are present it does not appear to increase the chance of developing endometriosis or infertility.
Synthesis and characterization of biologically active recombinant elk (show KCNH8 ELISA Kits) and horse FSH (show BRD2 ELISA Kits).
The 104-109 region of the beta eLH/CG subunit is essential for the secretion of a fully folded beta alpha eLH/CG and for its FSH (show BRD2 ELISA Kits) activity but not for its LH activity.
Changes in the expression of genes encoding beta-LH and GnRH-R (show GNRHR ELISA Kits) were also demonstrated across the estrous cycle in swine
This study determined the cDNA sequences of the luteinizing hormone beta-subunit (LHB) from Japanese White (JW), New Zealand White (NZW), and Dutch-Belted (Dutch) rabbits, and we compared these LHB sequences with those of other mammals.
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
luteinizing hormone beta polypeptide
, luteinizing hormone subunit beta
, lutropin beta chain
, lutropin subunit beta
, Luteinizing hormone (lutropin) subunit beta
, interstitial cell stimulating hormone, beta chain
, luteinizing hormone beta subunit
, interstitial cell-stimulating hormone
, leutenising hormone beta
, lutropin/choriogonadotropin beta chain
, lutropin/choriogonadotropin subunit beta
, LH-beta subunit