You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human MALT1 antibody for Immunohistochemistry

Recommended MALT1 Antibody (supplied by: Log in to see )

Antigen
Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) Antibodies
  • A630046N12
  • D430033E09Rik
  • malt1
  • MALT1
  • mlt
  • MLT
  • mlt1
  • MLT1
Epitope
AA 43-57
20
10
10
6
5
4
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
177
36
35
Host
Rabbit
106
72
12
Clonality
Polyclonal
Conjugate
This MALT1 antibody is un-conjugated
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
159
87
73
64
52
50
45
40
37
11
3
3
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN2470129
$ 481.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011340706 ABIN1873591 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN3023032 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2892375 IF IHC WB Rabbit Asn324 Log in to see Polyclonal
0.0011340706 ABIN2306072 FACS IF IP IHC ELISA WB Mouse IgG1 kappa AA 701-808 Log in to see MT1-410
0.0011340706 ABIN3185445 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0011340706 ABIN2306069 FACS IF IP IHC ELISA WB Mouse IgG1 kappa AA 701-808 Log in to see SPM578
0.0011340706 ABIN1873590 IHC Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2625044 IF IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0011340706 ABIN2306057 IHC WB Rabbit IgG AA 43-57 Log in to see Polyclonal
0.0011340706 ABIN2405162 IHC WB Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN1088940 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN1088939 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.0011340706 ABIN2306054 IHC WB Mouse IgG1 AA 701-808 Log in to see 10F48
0.0011340706 ABIN2306055 IP IHC WB Rabbit IgG AA 646-885 Log in to see Polyclonal
0.0011340706 ABIN2306058 IHC WB Mouse IgG1 AA 701-808 Log in to see 9F92
0.0011340706 ABIN3025290 FACS IF IHC WB Mouse IgG1, kappa AA 701-808 Log in to see MT1-410
0.0011340706 ABIN3025291 IHC Mouse IgG1, kappa AA 701-808 Log in to see MT1-410
0.0011340706 ABIN3025288 IHC Mouse IgG1, kappa AA 701-808 Log in to see 4NMT-3
0.0011340706 ABIN3025287 IF IHC WB Mouse IgG1, kappa AA 701-808 Log in to see 4NMT-3
0.0011340706 ABIN4230977 IHC Mouse IgG2a Log in to see 3A2

Similar anti-MALT1 Antibodies

Application / Reactivity Human
ELISA 60 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 52 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 45 Antibodies
Immunofluorescence (IF) 64 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 38 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 40 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 87 Antibodies
Immunoprecipitation (IP) 48 Antibodies
Western Blotting (WB) 147 Antibodies

General

Antigen Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) Antibodies
Epitope AA 43-57
(20), (10), (10), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(177), (36), (35)
Host Rabbit
(106), (72), (12)
Clonality
Polyclonal
Conjugate This MALT1 antibody is un-conjugated
(5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(159), (87), (73), (64), (52), (50), (45), (40), (37), (11), (3), (3), (1), (1), (1)
Supplier Log in to see

Product Details anti-MALT1 Antibody

Target Details MALT1 Application Details Handling Images
Purification Protein G Column
Immunogen MALT1 antibody was raised against amino acids 43 - 57 of MALT1 (Human).
Isotype IgG

Target Details MALT1

Product Details anti-MALT1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MALT1 (MALT1 Antibody Abstract)
Background MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB. MALT1 is thought to play an importantrole in NF-kappaB signaling by enchancing NF-kappaB activation through interaction with Bcl10 (Ho et al., 2005). Interaction between MALT1 and Bcl10 mediates IKK activation in vitro through facilitatiing the ubiquitination of NEMO by the ubiquitin-conjugating enzyme UBC13. Four recurrent chromosomal translocations have been described in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid issue (MALT) type. Two of them,t(14,18)(q32,q21) and t(11,18)(q21,q21), are found in 30 % to 50 % of extranodal MALT lymphomas. The first translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in the deregulation of MALT1 expression, whereas the second translocation generates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1). The other two much rarer translocations, t(1,14)(p22,q32)and t(1,2)(p22,p12), target Bcl10 gene on the short arm of chromosome 1. Translocations involving Bcl10 and MALT1 may lead to elevated NF-kappaB activity in MALT B-cell lymphoma. Two alternatively spliced transcript variants encoding different isoforms (a and b) have been described for the MALT1 gene. Human MALT1 isoform a is an amino acid protein of 824 amino acids, and human MALT1 isoform b is an amino acid protein of 813 amino acids.
Gene ID 10892
UniProt Q9UDY8
Research Area Signaling, Apoptosis/Necrosis
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MALT1 Antibody Target Details MALT1 Handling Images back to top
Application Notes MALT1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-MALT1 Antibody Target Details MALT1 Application Details Images back to top
Format Liquid
Buffer PBS, 0.2 % gelatin, 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment MALT1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Images

Product Details anti-MALT1 Antibody Target Details MALT1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MALT1 antibody (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1) (AA 43-57) (ABIN2470129) anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 43-57) antibody