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anti-Human MALT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MALT1 Antibody (supplied by: Log in to see )

Antigen
Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) Antibodies
  • A630046N12
  • D430033E09Rik
  • malt1
  • MALT1
  • mlt
  • MLT
  • mlt1
  • MLT1
Epitope
AA 43-57
20
10
10
6
5
4
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
177
36
35
Host
Rabbit
106
72
12
Clonality
Polyclonal
Conjugate
This MALT1 antibody is un-conjugated
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
159
86
73
64
52
50
45
40
38
11
3
3
1
1
1
Supplier
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Catalog No. ABIN372433
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008973577 ABIN452339 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0008973577 ABIN1687750 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
0.0008973577 ABIN298719 IHC (p) WB Rabbit IgG AA 43-57 Log in to see Polyclonal
0.0008973577 ABIN1688558 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0008973577 ABIN498450 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.0008973577 ABIN957209 IHC (fro) IHC (p) IP WB Rabbit AA 646-885 Log in to see Polyclonal
0.0008973577 ABIN462475 IHC (p) WB Mouse IgG1 Log in to see CD8
0.0008973577 ABIN609035 IHC (p) WB Mouse IgG1 AA 701-808 Log in to see
0.0008973577 ABIN1736688 IHC (p) WB Rabbit IgG AA 43-57 Log in to see Polyclonal
0.0008973577 ABIN1819925 IHC (p) WB Mouse IgG1 C-Term, AA 701-808 Log in to see 50
0.0008973577 ABIN2586823 IHC (p) Mouse IgG1 Log in to see 4C3
0.0008973577 ABIN2475476 IHC (p) WB Mouse IgG1 Log in to see 50 3
0.0008973577 ABIN905509 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.0008973577 ABIN905511 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008973577 ABIN1032396 IHC (p) WB Mouse IgG1 Log in to see 50
0.0008973577 ABIN873227 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008973577 ABIN2586817 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008973577 ABIN4332485 FACS ICC IF IHC (p) WB Mouse IgG1 kappa Log in to see SPM578
0.0008973577 ABIN4332486 FACS ICC IF IHC (p) WB Mouse IgG1 kappa Log in to see SPM578
0.0008973577 ABIN4332484 FACS ICC IF IHC (p) WB Mouse IgG1 kappa Log in to see SPM578

Top referenced anti-MALT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MALT1 Antibodies

Application / Reactivity Human
ELISA 60 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 52 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 45 Antibodies
Immunofluorescence (IF) 64 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 38 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 40 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 87 Antibodies
Immunoprecipitation (IP) 48 Antibodies
Western Blotting (WB) 147 Antibodies

General

Antigen Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) Antibodies
Epitope AA 43-57
(20), (10), (10), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(177), (36), (35)
Host Rabbit
(106), (72), (12)
Clonality
Polyclonal
Conjugate This MALT1 antibody is un-conjugated
(5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(159), (86), (73), (64), (52), (50), (45), (40), (38), (11), (3), (3), (1), (1), (1)
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Product Details anti-MALT1 Antibody

Target Details MALT1 Application Details Handling Images
Sequence ELLDQAPEGR GWRRL
Specificity This antibody recognizes MALT1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein G Chromatography.
Immunogen Synthetic peptide corresponding to amino acids 43-57 of Human MALT1.
Isotype IgG

Target Details MALT1

Product Details anti-MALT1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MALT1 (MALT1 Antibody Abstract)
Background MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB. MALT1 is thought to play an importantrole in NF-kappaB signaling by enchancing NF-kappaB activation through interaction with Bcl10 (Ho et al., 2005). Interaction between MALT1 and Bcl10 mediates IKK activation in vitro through facilitatiing the ubiquitination of NEMO by the ubiquitin-conjugating enzyme UBC13. Four recurrent chromosomal translocations have been described in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid issue (MALT) type. Two of them,t(14,18)(q32,q21) and t(11,18)(q21,q21), are found in 30 % to 50 % of extranodal MALT lymphomas. The first translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in the deregulation of MALT1 expression, whereas the second translocation generates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1). The other two much rarer translocations, t(1,14)(p22,q32)and t(1,2)(p22,p12), target Bcl10 gene on the short arm of chromosome 1. Translocations involving Bcl10 and MALT1 may lead to elevated NF-kappaB activity in MALT B-cell lymphoma. Two alternatively spliced transcript variants encoding different isoforms (a and b) have been described for the MALT1 gene. Human MALT1 isoform a is an amino acid protein of 824 amino acids, and human MALT1 isoform b is an amino acid protein of 813 amino acids.Synonyms: MALT lymphoma-associated translocation, MLT, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase
Gene ID 10892
NCBI Accession NP_006776
UniProt Q9UDY8
Research Area Signaling, Apoptosis/Necrosis
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-MALT1 Antibody Target Details MALT1 Handling Images back to top
Application Notes Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 0.5-2 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-MALT1 Antibody Target Details MALT1 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product Details anti-MALT1 Antibody Target Details MALT1 Application Details Handling back to top
Supplier Images
 image for anti-MALT1 antibody (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1) (AA 43-57) (ABIN372433) anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 43-57) antibody