Browse our MALT1 Proteins (MALT1)

On www.antibodies-online.com are 6 Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) Proteins from 3 different suppliers available. Additionally we are shipping MALT1 Antibodies (193) and many more products for this protein. A total of 207 MALT1 products are currently listed.
Synonyms:
A630046N12, D430033E09Rik, MALT1, MLT, MLT1
list all proteins Gene Name GeneID UniProt
MALT1 10892 Q9UDY8
MALT1 240354 Q2TBA3
Rat MALT1 MALT1 307366  

MALT1 Proteins (MALT1) by Origin

More Proteins for MALT1 Interaction Partners

Human Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) interaction partners

  1. Authors utilized transcriptomic data and experimental evidences to prove that miR (show MLXIP Proteins)-181d was a novel regulator of NFkappaB (show NFKB1 Proteins) signaling pathway by directly repressing MALT1, leading to induced PN markers and reduced MES (show ME1 Proteins) genes.

  2. Taken together, this present study indicates that miR (show MLXIP Proteins)-649 promotes herpes simplex virus type 1 replication through regulation of the MALT1-mediated antiviral signaling pathway and suggests a promising target for antiviral therapies.

  3. These results demonstrate a key role for the proteolytic activity of MALT1 in PEL, and provide a rationale for the pharmacological targeting of MALT1 in PEL therapy.

  4. MALT1 deficiency or pharmacological inhibition of MALT1 catalytic activity inhibits pathogenic mutant CARD14 (show CARD14 Proteins)-induced cytokine and chemokine (show CCL1 Proteins) expression in human primary keratinocytes.

  5. results unveil HOIL1 (show RBCK1 Proteins) as a negative regulator of lymphocyte activation cleaved by MALT1.

  6. CARD14 (show CARD14 Proteins)/MALT1-mediated signaling in keratinocytes has a role in psoriasis [review]

  7. Psoriasis mutations disrupt CARD14 (show CARD14 Proteins) autoinhibition promoting BCL10 (show BCL10 Proteins)-MALT1-dependent NF-kappaB (show NFKB1 Proteins) activation

  8. Studies indicate that t(11;18)(q21;q21) translocation involves MALT1 (MALT lymphoma translocation protein 1) gene.

  9. Targeting MALT1 proteolytic activity in autoimmune disease and B-cell lymphoma might not be a successful strategy. (Review)

  10. Data show that Bruton tyrosine kinase (BTK (show BTK Proteins))inhibitor Ibrutinib augments MALT lymphoma associated translocation protein (MALT1) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC (show ABCB6 Proteins)) of diffuse large B cell lymphoma (DLBCL).

Mouse (Murine) Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) interaction partners

  1. MALT1 function is required in B cells for germinal center formation.

  2. Studies indicate an important role for mucosa associated lymphoid tissue lymphoma translocation gene 1 protein (MALT1) in the development of experimental autoimmune encephalomyelitis (EAE)

  3. Targeting MALT1 proteolytic activity in autoimmune disease and B-cell lymphoma might not be a successful strategy. (Review)

  4. TCR-induced alternative splicing augments MALT1 scaffolding to enhance downstream signalling and to promote optimal T-cell activation.

  5. MALT1-dependent NF-kappaB (show NFKB1 Proteins) activation is crucial for the development of EGFR (show EGFR Proteins)-associated solid-tumor progression

  6. By regulating linear ubiquitination, MALT1 is both a positive and negative pleiotropic regulator of the canonical NF-kappaB (show NFKB1 Proteins) pathway.

  7. Results demonstrate that MALT1 protease activity plays key roles in both innate and adaptive immune responses, and in regulating immune homeostasis in vivo.

  8. data demonstrate that MALT1 ubiquitination is critical for the engagement of CBM and IKK (show CHUK Proteins) complexes, thereby directing platelet signals to the NF-kappaB (show NFKB1 Proteins) pathway.

  9. Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.

  10. These results reveal distinct threshold and modulatory functions of Malt1 that differentially control lymphocyte differentiation and activation pathways.

MALT1 Protein Profile

Protein Summary

This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with MALT1

  • mucosa associated lymphoid tissue lymphoma translocation gene 1a (malt1a)
  • mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1)
  • mucosa associated lymphoid tissue lymphoma translocation gene 1 (malt1)
  • mucosa associated lymphoid tissue lymphoma translocation gene 1 (Malt1)
  • A630046N12 protein
  • D430033E09Rik protein
  • MALT1 protein
  • MLT protein
  • MLT1 protein

Protein level used designations for MALT1

mucosa associated lymphoid tissue lymphoma translocation gene 1 , paracaspace , mucosa associated lymphoid tissue lymphoma translocation protein 1 , mucosa-associated lymphoid tissue lymphoma translocation protein 1-like , MALT associated translocation , MALT lymphoma-associated translocation , MALT-lymphoma associated translocation , caspase-like protein , mucosa-associated lymphoid tissue lymphoma translocation protein 1 , paracaspase , mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

GENE ID SPECIES
259196 Danio rerio
468549 Pan troglodytes
476188 Canis lupus familiaris
495220 Xenopus laevis
504994 Bos taurus
696354 Macaca mulatta
100016169 Monodelphis domestica
100153830 Sus scrofa
100590402 Nomascus leucogenys
100054579 Equus caballus
100478097 Ailuropoda melanoleuca
10892 Homo sapiens
240354 Mus musculus
307366 Rattus norvegicus
415336 Gallus gallus
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