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anti-Human Mu Opioid Receptor Antibodies:
anti-Rat (Rattus) Mu Opioid Receptor Antibodies:
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This study demonstrated that brain regions particularly related to the somatosensory component of pain processing are modulated by variations in OPRM1 (show OPRM1 Antibodies).
siRNA-loaded RVG exosomes significantly reduced MOR mRNA and protein levels. Surprisingly, MOR siRNA delivered by the RVG exosomes strongly inhibited morphine relapse via the down-regulation of MOR expression
No association has been found between the OPRM1 (show OPRM1 Antibodies) A118G SNP and pain perception in Chinese cancer patients.
result indicated that Caucasians carrying the G allele (AG + GG) of the A118G polymorphism in the mu-opioid receptor (show OPRM1 Antibodies) gene were more likely to be addicted to smoking compared with those with the AA homozygote
we have identified for the first time a potential mechanism that involves the essential splicing factor (show SLU7 Antibodies) ASF/SF2 (show SRSF1 Antibodies) through which morphine regulates splicing specificity of the MOR (show OPRM1 Antibodies) encoding gene, OPRM1 (show OPRM1 Antibodies).
OPRM1 (show OPRM1 Antibodies) A118G was not associated with nicotine craving in adolescent novice smokers.
Significant differences in mean dose consumption were seen among the genotypic groups of the OPRM1 (show OPRM1 Antibodies) A118G and UGT2B7 (show UGT2B7 Antibodies) C802T variants. These variants were found to predict codeine consumption in the cohort overall and among Caucasians
Findings show that common OPRM1 (show OPRM1 Antibodies) intron 1 SNPs have replicable associations with heroin addiction, haplotype structure of rs3778150 and nearby SNPs may underlie the inconsistent associations between rs1799971 and heroin addiction
These investigations represent a reverse translational approach to investigating how the OPRM1 (show OPRM1 Antibodies) A118G polymorphism alters mesolimbic responses to opioids, which may elucidate mechanisms influencing both opioid and alcohol abuse in human populations
Study found that the OPRM1 (show OPRM1 Antibodies) A118G polymorphism produces significant variation in cortisol reactions to psychological stress among women
This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene.
micro opioid receptor isoform hMOR-1A2
, mu opiate receptor
, mu opioid receptor hMOR-1a
, mu-type opioid receptor