Browse our ORAI1 (ORAI1) ELISA Kits

Full name:
ORAI Calcium Release-Activated Calcium Modulator 1 ELISA Kits (ORAI1)
On www.antibodies-online.com are 4 ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) ELISA Kits from 1 different suppliers available. Additionally we are shipping ORAI1 Antibodies (121) and and many more products for this protein. A total of 138 ORAI1 products are currently listed.
Synonyms:
CRACM1, D730049H07Rik, im:7146264, LOC100218031, orai-1, ORAI1, orai2, ORAT1, RGD1311873, Tmem142a, tmem142b, zgc:109721
list all ELISA KIts Gene Name GeneID UniProt
ORAI1 84876 Q96D31
ORAI1 109305 Q8BWG9
ORAI1 304496 Q5M848

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More ELISA Kits for ORAI1 Interaction Partners

Zebrafish ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. Orai1 is localized to the cleavage furrow during cytokinesis of the first and second cell division cycles in zebrafish embryos.

  2. The findings identify ORAI1 as an important regulator of cardiac and skeletal muscle function and provide evidence linking ORAI1-mediated calcium signaling to sarcomere integrity and cardiomyocyte function.

Xenopus laevis ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. The Orai1 actively recycles between an endosomal compartment and the cell membrane through a Rho-dependent endocytic pathway.

Silk Worm ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. STIM1 (show STIM1 ELISA Kits) and Orai1 are essential components of the signal transduction cascade that regulates sex pheromone production.

Human ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. RASSF4 (show RIN2 ELISA Kits) controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6 (show ARF6 ELISA Kits)-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes.

  2. findings provide evidence for a role for Orai1 and Orai2 (show ORAI2 ELISA Kits), in SOCE and migration in the human HL60 promyeloblastic cell line

  3. findings demonstrate that Ca2 (show CA2 ELISA Kits)+ influx via store-operated CRAC channels is essential for CaCC (show CLCA1 ELISA Kits) activation, chloride secretion, and sweat production in humans and mice.

  4. F. vulgare fruits extract and its hexane fraction strongly blocked ORAI1 currents and tyrosinase (show TYR ELISA Kits) activity and significantly inhibited UV-induced melanogenesis

  5. Aptamer Y1 binds to Orai1 and inhibits Ca2 (show CA2 ELISA Kits)+ influx into antigen-activated mast cells

  6. Elevated Orai1 and STIM1 (show STIM1 ELISA Kits) expressions upregulate MACC1 (show MACC1 ELISA Kits) expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  7. Orai1 expression was higher in colorectal cancer (CRC (show CALR ELISA Kits)) tissues than adjacent non-cancerous tissues; increased expression of Orai1 was observed in invasive CRC (show CALR ELISA Kits) cell lines and ectopic expression of Orai1 enhanced cell proliferation and inhibited apoptosis; the Akt (show AKT1 ELISA Kits)/GSK3beta (show GSK3b ELISA Kits) pathway contributed to Orai1 effects in CRC (show CALR ELISA Kits) cells, and Orai1 was a direct target of miR (show MLXIP ELISA Kits)-519

  8. Store-operated Ca(2 (show CA2 ELISA Kits)+) entry activates a mitochondrial redox transient which is dependent on NCLX (show SLC24A6 ELISA Kits) and is required for preventing Orai1 inactivation through oxidation of a critical cysteine (Cys195) in the third transmembrane helix of Orai1.

  9. CRAC channel functions as a hexamer of Orai1 subunits

  10. A novel heterozygous c.290C>G (p.S97C) mutation in ORAI1 causing a mild- and late-onset tubular aggregate myopathy and congenital miosis via constitutive activation of the CRAC channel.

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) interaction partners

  1. Orai1 (show TMEM132A ELISA Kits) enhances muscle endurance by promoting fatigue-resistant type I fiber content

  2. findings demonstrate that Ca2 (show CA2 ELISA Kits)+ influx via store-operated CRAC channels is essential for CaCC (show CLCA1 ELISA Kits) activation, chloride secretion, and sweat production in humans and mice.

  3. Mouse embryos deficient in Orai1 (show TMEM132A ELISA Kits), Klf2 (show KLF2 ELISA Kits), or Klf4 (show KLF4 ELISA Kits) showed a significantly reduced lymphatic density and impaired lymphatic development.

  4. Store operated calcium entry negatively regulates the Smad1 (show SMAD1 ELISA Kits) signaling pathway and inhibits Col (show HDAC1 ELISA Kits) IV protein production in glomerular mesangial cells.

  5. F. vulgare fruits extract and its hexane fraction strongly blocked ORAI1 (show TMEM132A ELISA Kits) currents and tyrosinase (show TYR ELISA Kits) activity and significantly inhibited UV-induced melanogenesis

  6. mice lacking acinar Orai1 (show TMEM132A ELISA Kits) exhibited intestinal bacterial outgrowth and dysbiosis, ultimately causing systemic translocation, inflammation, and death.

  7. these data indicate for the first time a functional interaction between Orai1 (show TMEM132A ELISA Kits), TRPC1 (show TRPC1 ELISA Kits), and CaV1.2 (show CACNA1C ELISA Kits) channels in Vascular Smooth Muscle Cells, confirming that upon agonist stimulation, vessel contraction involves Ca(2 (show CA2 ELISA Kits)+) entry due to co-activation of Orai1 (show TMEM132A ELISA Kits)- and TRPC1 (show TRPC1 ELISA Kits)-dependent store-operated Ca(2 (show CA2 ELISA Kits)+) channels and L-type Ca(2 (show CA2 ELISA Kits)+) channels.

  8. reveal that Orai1 (show TMEM132A ELISA Kits)(-/-) male mice are sterile and have severe defects in spermatogenesis, with prominent deficiencies in mid- to late-stage elongating spermatid development

  9. In Dicer (show DICER1 ELISA Kits)-deficient mice Orai1 (show TMEM132A ELISA Kits) was down-regulated at mRNA and protein level in CD4 (show CD4 ELISA Kits)+ T cells.

  10. results identified the ORAI-NOX2 (show CYBB ELISA Kits) feedback loop as a determinant of monocyte immune responses.

ORAI1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).

Alternative names and synonyms associated with ORAI1

  • ORAI calcium release-activated calcium modulator 1b (orai1b) Elisa Kit
  • ORAI calcium release-activated calcium modulator 1 (orai1) Elisa Kit
  • ORAI calcium release-activated calcium modulator 1 (ORAI1) Elisa Kit
  • ORAI calcium release-activated calcium modulator 1 (Orai1) Elisa Kit
  • ORAI calcium release-activated calcium modulator 1 (LOC100218031) Elisa Kit
  • ORAI calcium release-activated calcium modulator 2 (orai2) Elisa Kit
  • CRACM1 Elisa Kit
  • D730049H07Rik Elisa Kit
  • im:7146264 Elisa Kit
  • LOC100218031 Elisa Kit
  • orai-1 Elisa Kit
  • ORAI1 Elisa Kit
  • orai2 Elisa Kit
  • ORAT1 Elisa Kit
  • RGD1311873 Elisa Kit
  • Tmem142a Elisa Kit
  • tmem142b Elisa Kit
  • zgc:109721 Elisa Kit

Protein level used designations for ORAI1

ORAI calcium release-activated calcium modulator 1 , calcium release-activated calcium channel protein 1 , protein orai-1 , transmembrane protein 142A , protein orai-2 , transmembrane protein 142B , calcium release-activated calcium modulator 1 , calcium release-activated calcium channel 1

GENE ID SPECIES
402892 Danio rerio
403390 Xenopus laevis
473293 Pan troglodytes
700190 Macaca mulatta
100125061 Xenopus (Silurana) tropicalis
100188931 Bombyx mori
100218031 Taeniopygia guttata
84876 Homo sapiens
486261 Canis lupus familiaris
100154923 Sus scrofa
517688 Bos taurus
109305 Mus musculus
304496 Rattus norvegicus
416845 Gallus gallus
734537 Xenopus laevis
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