Browse our PKB (PKB) ELISA Kits

Full name:
Protein Kinase B ELISA Kits (PKB)
On www.antibodies-online.com are 24 Protein Kinase B (PKB) ELISA Kits from 5 different suppliers available. Additionally we are shipping PKB Antibodies (8) and many more products for this protein. A total of 32 PKB products are currently listed.
Synonyms:
AKT, CADTK, CAKB, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, PYK2, Rac, RAFTK

More ELISA Kits for PKB Interaction Partners

Human Protein Kinase B (PKB) interaction partners

  1. Our findings suggest that Pyk2 (show PTK2B ELISA Kits) plays an important role in the coordination of stabilization of beta-catenin (show CTNNB1 ELISA Kits) in the crosstalk between Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) and Wnt (show WNT2 ELISA Kits)/Ca(2 (show CA2 ELISA Kits)+) signaling pathways upon Wnt3a (show WNT3A ELISA Kits) stimulation in differentiating hNPCs.

  2. STIM1 (show STIM1 ELISA Kits)-induced Ca(2 (show CA2 ELISA Kits)+) signaling activates Pyk2 (show PTK2B ELISA Kits) to inhibit the interaction of VE-PTP (show PTPRB ELISA Kits) and VE-cadherin (show CDH5 ELISA Kits) and hence increase endothelial permeability.

  3. Ascites and CCL18 (show CCL18 ELISA Kits) stimulate the phosphorylation and expression of Pyk2 (show PTK2B ELISA Kits), which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin (show 0 ELISA Kits), a process in part mediated through the PI3-kinase (show PIK3CA ELISA Kits)-Akt/PKB (show AKT1 ELISA Kits) cell survival pathway. These results provide further rationale for clinical investigation of relaxin (show 0 ELISA Kits) as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 (show PTK2B ELISA Kits) is a common downstream effector of ErbB (show EGFR ELISA Kits) and IL8 (show IL8 ELISA Kits) receptors, and that PYK2 (show PTK2B ELISA Kits) integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 (show PTK2B ELISA Kits) is a key downstream signaling molecules of CCR7 (show CCR7 ELISA Kits) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 (show PTK2B ELISA Kits) as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2 (show PTK2B ELISA Kits)-focal adhesion targeting domain interacts with and binds to leupaxin (show LPXN ELISA Kits).

  10. Src (show SRC ELISA Kits) has a role in priming Pyk2 (show PTK2B ELISA Kits) (but not FAK (show PTK2 ELISA Kits)) phosphorylation and subsequent activation downstream of integrins

Mouse (Murine) Protein Kinase B (PKB) interaction partners

  1. TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) complex upregulation of OPN (show SPP1 ELISA Kits) expression is mediated by transcription factor SOX9 (show SOX9 ELISA Kits) in an mTOR (show FRAP1 ELISA Kits)-independent manner. Moreover, ablation of OPN (show SPP1 ELISA Kits) by deficient TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) complex contributed to inactivation of AKT (show AKT1 ELISA Kits) in TSC (show SLC12A3 ELISA Kits) cells

  2. Our results suggest that increasing Akt (show AKT1 ELISA Kits)/ NF-kappaB (show NFKB1 ELISA Kits) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (show AKT1 ELISA Kits) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (show AKT1 ELISA Kits) activation that tracks both the biochemical state and the physical location of Akt (show AKT1 ELISA Kits), is reported.

  6. Psgl-1 (show SELPLG ELISA Kits) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (show AKT1 ELISA Kits) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (show HSP90 ELISA Kits) and the PI3K/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) pathway in prostate cancer.

  8. Furthermore, Leishmania RNA virus 1-induced TLR-3 (show TLR3 ELISA Kits) activation promoted parasite persistence by enhancing macrophage survival through Akt (show AKT1 ELISA Kits) activation in a manner partially dependent on miR (show MLXIP ELISA Kits)-155.

  9. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (show CCL2 ELISA Kits) proliferation, and was associated with inhibition of PI3K/Akt (show AKT1 ELISA Kits) signaling pathway through activation of GPR120 (show O3FAR1 ELISA Kits).

  10. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (show ROS1 ELISA Kits)) generation, RhoA (show RHOA ELISA Kits) activity and normalizing Akt (show AKT1 ELISA Kits)/GSK3beta (show GSK3b ELISA Kits) signaling pathways.

Pig (Porcine) Protein Kinase B (PKB) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits) signaling and suppressing the activation of TLR4 (show TLR4 ELISA Kits) and/or NOD2 (show NOD2 ELISA Kits) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt (show AKT1 ELISA Kits) signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 (show AKT1 ELISA Kits) could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 (show AKT1 ELISA Kits) play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT (show AKT1 ELISA Kits) is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (show LRP2 ELISA Kits) is the sensor that determines whether cells will be protected or injured by albumin (show ALB ELISA Kits); it binds protein kinase B (PKB (show AKT1 ELISA Kits)) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB (show AKT1 ELISA Kits) in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt (show AKT1 ELISA Kits))was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt (show AKT1 ELISA Kits) signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Goat Protein Kinase B (PKB) interaction partners

  1. Exogenous AKT (show AKT1 ELISA Kits) was transcribed, and AKT (show AKT1 ELISA Kits) was overexpressed, inducing the phosphorylation of p70S6K (show RPS6KB1 ELISA Kits) (Thr389) and 4E-BP1 (show EIF4EBP1 ELISA Kits) (Thr37/46) in goat fetal fibroblasts.

Cow (Bovine) Protein Kinase B (PKB) interaction partners

  1. These results demonstrate that activation of AKT (show AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 (show CTNNB1 ELISA Kits) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (show CAV1 ELISA Kits) scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 ELISA Kits) signaling

  3. TG2 (show TGM2 ELISA Kits) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (show AKT1 ELISA Kits) signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt (show AKT1 ELISA Kits) activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (show GSK3b ELISA Kits), and NF-kappaB (show NFKB1 ELISA Kits).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (show NOX1 ELISA Kits), reactive oxygen species, and PI3-kinase (show PIK3CA ELISA Kits) in stimulated NO release.

  6. PI3K/Akt (show AKT1 ELISA Kits) and p53 (show TP53 ELISA Kits) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 ELISA Kits), mTOR (show FRAP1 ELISA Kits), p70S6K (show RPS6KB1 ELISA Kits), and ERK1/2 (show MAPK1/3 ELISA Kits).

  8. Gab1 tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B (show AKT1 ELISA Kits) and endothelial nitric-oxide synthase (show NOS3 ELISA Kits) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (show NOS3 ELISA Kits) phosphorylation and suppresses tumor necrosis factor alpha (show TNF ELISA Kits)-induced endothelial cell apoptosis by activating AKT1 (show AKT1 ELISA Kits).

  10. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 ELISA Kits) and activates mTOR (show FRAP1 ELISA Kits) and ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits) signaling in an AKT (show AKT1 ELISA Kits)-independent manner

PKB Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PKB

  • protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • thymoma viral proto-oncogene 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) Elisa Kit
  • AKT Elisa Kit
  • CADTK Elisa Kit
  • CAKB Elisa Kit
  • FADK2 Elisa Kit
  • FAK2 Elisa Kit
  • PKB Elisa Kit
  • PKB/Akt Elisa Kit
  • PKBalpha Elisa Kit
  • PTK Elisa Kit
  • PYK2 Elisa Kit
  • Rac Elisa Kit
  • RAFTK Elisa Kit

Protein level used designations for Protein Kinase B (PKB) ELISA Kits

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , AKT1 kinase , PKB alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1 , RAC-beta serine/threonine-protein kinase

GENE ID SPECIES
2185 Homo sapiens
11651 Mus musculus
24185 Rattus norvegicus
100126861 Sus scrofa
100860904 Capra hircus
280991 Bos taurus
100294652 Ovis aries
449021 Canis lupus familiaris
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