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Browse our PKB (PKB) ELISA Kits

Full name:
Protein Kinase B ELISA Kits (PKB)
On www.antibodies-online.com are 22 Protein Kinase B (PKB) ELISA Kits from 4 different suppliers available. Additionally we are shipping PKB Antibodies (8) and many more products for this protein. A total of 30 PKB products are currently listed.
Synonyms:
AKT, CADTK, CAKB, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, PYK2, Rac, RAFTK

More ELISA Kits for PKB Interaction Partners

Human Protein Kinase B (PKB) interaction partners

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin (show 0 ELISA Kits), a process in part mediated through the PI3-kinase (show PIK3CA ELISA Kits)-Akt/PKB (show AKT1 ELISA Kits) cell survival pathway. These results provide further rationale for clinical investigation of relaxin (show 0 ELISA Kits) as a potential therapeutic in preeclampsia.

  2. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  3. Studies suggest that PYK2 (show PTK2B ELISA Kits) is a common downstream effector of ErbB (show EGFR ELISA Kits) and IL8 (show IL8 ELISA Kits) receptors, and that PYK2 (show PTK2B ELISA Kits) integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  4. Pyk2 (show PTK2B ELISA Kits) is a key downstream signaling molecules of CCR7 (show CCR7 ELISA Kits) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  5. Phosphoproteomic analysis identifies FAK2 (show PTK2B ELISA Kits) as a potential therapeutic target for tamoxifen resistance in breast cancer.

  6. Pyk2 (show PTK2B ELISA Kits)-focal adhesion targeting domain interacts with and binds to leupaxin (show LPXN ELISA Kits).

  7. Src (show SRC ELISA Kits) has a role in priming Pyk2 (show PTK2B ELISA Kits) (but not FAK (show PTK2 ELISA Kits)) phosphorylation and subsequent activation downstream of integrins

  8. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  9. FAK (show PTK2 ELISA Kits) and PYK2 (show PTK2B ELISA Kits) functioned redundantly to promote the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway by phosphorylating GSK3beta(Y216) to reinforce pathway output-beta-catenin (show CTNNB1 ELISA Kits) accumulation and intestinal tumorigenesis.

  10. This study identified Pyk2 (show PTK2B ELISA Kits) as a cellular component required for the intracellular trafficking of HPV16 during infection.

Mouse (Murine) Protein Kinase B (PKB) interaction partners

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt (show AKT1 ELISA Kits) phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt (show AKT1 ELISA Kits) indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt/mTOR and MAPK pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt (show AKT1 ELISA Kits)-Nrf2 (show NFE2L2 ELISA Kits) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (show INS ELISA Kits)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (show IRS1 ELISA Kits)/PDPK1 (show PDPK1 ELISA Kits)/AKT (show AKT1 ELISA Kits) insulin (show INS ELISA Kits) pathway by interacting with its GAP ASAP2 (show ASAP2 ELISA Kits) and activating PDPK1 (show PDPK1 ELISA Kits). This research may provide new insights into GTPase (show RACGAP1 ELISA Kits)-mediated insulin (show INS ELISA Kits) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (show INS ELISA Kits) sensitizati

  6. Taken together, our findings imply that KLF15 (show KLF15 ELISA Kits) possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) axis. KLF15 (show KLF15 ELISA Kits) may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (show MEN1 ELISA Kits) binds on the promoter of Inhbb (show INHBB ELISA Kits) gene where it favours the recruitment of Ezh2 (show EZH2 ELISA Kits) via an indirect mechanism involving Akt (show AKT1 ELISA Kits)-phosphorylation.

  8. A role of AKT (show AKT1 ELISA Kits) in the regulatory T cell differentiation process. TGF-beta (show TGFB1 ELISA Kits) induces the phosphorylation of Akt (show AKT1 ELISA Kits) in CD4 (show CD4 ELISA Kits)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (show INS ELISA Kits) sensitivity in adipose tissue of obese mice via Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling partly, which could be regarded as novel opportunities for treatment of insulin (show INS ELISA Kits) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (show CYP2J2 ELISA Kits) and epoxyeicosatrienoic acids enhanced Akt1 (show AKT1 ELISA Kits) nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Pig (Porcine) Protein Kinase B (PKB) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits) signaling and suppressing the activation of TLR4 (show TLR4 ELISA Kits) and/or NOD2 (show NOD2 ELISA Kits) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt (show AKT1 ELISA Kits) signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 (show AKT1 ELISA Kits) could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 (show AKT1 ELISA Kits) play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT (show AKT1 ELISA Kits) is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (show LRP2 ELISA Kits) is the sensor that determines whether cells will be protected or injured by albumin (show ALB ELISA Kits); it binds protein kinase B (PKB (show AKT1 ELISA Kits)) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB (show AKT1 ELISA Kits) in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt (show AKT1 ELISA Kits))was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt (show AKT1 ELISA Kits) signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Goat Protein Kinase B (PKB) interaction partners

  1. Exogenous AKT (show AKT1 ELISA Kits) was transcribed, and AKT (show AKT1 ELISA Kits) was overexpressed, inducing the phosphorylation of p70S6K (show RPS6KB1 ELISA Kits) (Thr389) and 4E-BP1 (show EIF4EBP1 ELISA Kits) (Thr37/46) in goat fetal fibroblasts.

Cow (Bovine) Protein Kinase B (PKB) interaction partners

  1. These results demonstrate that activation of AKT (show AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 (show CTNNB1 ELISA Kits) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (show CAV1 ELISA Kits) scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 ELISA Kits) signaling

  3. TG2 (show TGM2 ELISA Kits) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (show AKT1 ELISA Kits) signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt (show AKT1 ELISA Kits) activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta, and NF-kappaB (show NFKB1 ELISA Kits).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (show NOX1 ELISA Kits), reactive oxygen species, and PI3-kinase (show PIK3CA ELISA Kits) in stimulated NO release.

  6. PI3K/Akt (show AKT1 ELISA Kits) and p53 (show TP53 ELISA Kits) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 ELISA Kits), mTOR (show FRAP1 ELISA Kits), p70S6K (show RPS6KB1 ELISA Kits), and ERK1/2 (show MAPK1/3 ELISA Kits).

  8. Gab1 tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B (show AKT1 ELISA Kits) and endothelial nitric-oxide synthase (show NOS3 ELISA Kits) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (show NOS3 ELISA Kits) phosphorylation and suppresses tumor necrosis factor alpha (show TNF ELISA Kits)-induced endothelial cell apoptosis by activating AKT1 (show AKT1 ELISA Kits).

  10. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 ELISA Kits) and activates mTOR (show FRAP1 ELISA Kits) and ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits) signaling in an AKT (show AKT1 ELISA Kits)-independent manner

PKB Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PKB

  • protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • thymoma viral proto-oncogene 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) Elisa Kit
  • AKT Elisa Kit
  • CADTK Elisa Kit
  • CAKB Elisa Kit
  • FADK2 Elisa Kit
  • FAK2 Elisa Kit
  • PKB Elisa Kit
  • PKB/Akt Elisa Kit
  • PKBalpha Elisa Kit
  • PTK Elisa Kit
  • PYK2 Elisa Kit
  • Rac Elisa Kit
  • RAFTK Elisa Kit

Protein level used designations for Protein Kinase B (PKB) ELISA Kits

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , AKT1 kinase , PKB alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1 , RAC-beta serine/threonine-protein kinase

GENE ID SPECIES
2185 Homo sapiens
11651 Mus musculus
24185 Rattus norvegicus
100126861 Sus scrofa
100860904 Capra hircus
280991 Bos taurus
100294652 Ovis aries
449021 Canis lupus familiaris
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