Browse our anti-PKC delta (PKCd) Antibodies

Full name:
anti-Protein Kinase C, delta Antibodies (PKCd)
On www.antibodies-online.com are 293 Protein Kinase C, delta (PKCd) Antibodies from 29 different suppliers available. Additionally we are shipping PKC delta Kits (49) and PKC delta Proteins (25) and many more products for this protein. A total of 384 PKC delta products are currently listed.
Synonyms:
AI385711, D14Ertd420e, fb09d10, fv43b11, MAY1, nPKC-delta, Pkaca, PKC-delta, pkc-delta2, Pkcd, PKCdelta, PKC[d], PRKCD, tpa-1, wu:fb09d10, wu:fv43b11, zgc:56558

Most Popular Reactivities for anti-PKC delta (PKCd) Antibodies

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anti-Human PKC delta Antibodies:

anti-Mouse (Murine) PKC delta Antibodies:

anti-Rat (Rattus) PKC delta Antibodies:

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Top referenced anti-PKC delta Antibodies

  1. Human Monoclonal PKC delta Primary Antibody for IF, IP - ABIN967942 : Bell, Burns: Lipid activation of protein kinase C. in The Journal of biological chemistry 1991 (PubMed)
    Show all 5 references for 967942

  2. Human Polyclonal PKC delta Primary Antibody for IF, IHC (p) - ABIN197564 : Zhang, Keane, Zhu, Sharma, Rozengurt, Strieter, Dubinett, Huang: Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for 197564

  3. Human Polyclonal PKC delta Primary Antibody for IHC (p), WB - ABIN197068 : Van Kolen, Slegers: Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. in The FEBS journal 2006 (PubMed)
    Show all 2 references for 197068

  4. Human Polyclonal PKC delta Primary Antibody for IF, ELISA - ABIN1532521 : Mitchell, Barker, Martindale, Kamalati, Lowe, Page, Gusterson, Crompton: Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours. in Oncogene 1994 (PubMed)

  5. Human Polyclonal PKC delta Primary Antibody for IHC, ELISA - ABIN1531464 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)

More Antibodies against PKC delta Interaction Partners

Human Protein Kinase C, delta (PKCd) interaction partners

  1. PKCdelta is a critical regulator of signaling mechanisms of neutrophil-endothelium interaction in acute inflammation. Inhibition of PKCdelta in human endothelial cells and neutrophils reduced chemoattractant-induced neutrophil migration across TNF-alpha (show TNF Antibodies)-activated endothelium, and reduced expression of E-selectin (show SELE Antibodies) and ICAM-1 (show ICAM1 Antibodies). Shear rate and vascular geometry regulate the impact of PKCdelta inhibition of neutrophil-endot...

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (show HCK Antibodies)-dependent activation of PKCdelta, which stimulates PKCgamma (show PRKCG Antibodies), resulting in translocation of phosphorylated p47(phox).

  3. The interplay between intracellular progesterone receptor (show PGR Antibodies) and PRKCA (show PKCa Antibodies)-PRKCD plays a key role in migration and invasion of human glioblastoma cells.

  4. Amphiregulin (show AREG Antibodies) enhances VEGF-A (show VEGFA Antibodies) production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR (show MLXIP Antibodies)-206 via FAK (show PTK2 Antibodies)/c-Src (show SRC Antibodies)/PKCdelta pathway.

  5. In the present investigation, we demonstrated that miR486 is negatively associated with the expression of PKC-delta and could regulate the development of osteosarcoma. miR (show MLXIP Antibodies)-486 may be a potential target for the treatment of osteosarcoma

  6. PKCdelta and PKCepsilon (show PRKCE Antibodies) work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.

  7. These findings suggest that targeting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) or Akt (show AKT1 Antibodies) pathways may increase the efficacy of taxane chemotherapy in advanced human prostate cancers that have lost PKCdelta expression.

  8. description of a rare monogenic form of juvenile systemic lupus erythematosus caused by a novel but damaging homozygous mutation affecting the active region of PRKCD.

  9. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (show SRSF2 Antibodies)) to promote alternative splicing of PKCdeltaII.

  10. mechanistic studies, inhibition of SRC (show SRC Antibodies) and PKCdelta completely ablated the ability of MDA-7/IL-24 (show IL24 Antibodies) to reduce the Bcl-x(L (show BCL2L1 Antibodies))/(s) mRNA ratio and cell viability. These findings show that Bcl-x (show BCL2L1 Antibodies)(s) expression is an important mediator of MDA-7/IL-24 (show IL24 Antibodies)-induced cytotoxicity requiring the SRC (show SRC Antibodies)/PKCdelta signaling axis in NSCLC cells.

Mouse (Murine) Protein Kinase C, delta (PKCd) interaction partners

  1. study identifies a new role of Dual-AKAP1 (show AKAP1 Antibodies) in regulating mitochondrial trafficking through Miro-2 (show RHOT2 Antibodies), and supports a model in which PINK1 (show PINK1 Antibodies) and mitochondrial PKA participate in a similar neuroprotective signaling pathway to maintain dendrite connectivity

  2. Data suggest that enzyme activation by cAMP involves highly stable conformation of Prkar1a as it binds to Prkaca; glycine residue, G235, appears to function as hinge in B/C helix conserved in Prkar1a; this "Flipback" conformation plays role in cAMP association to A domain of Prkar1a. (Prkar1a = cyclic AMP-dependent protein kinase RIalpha subunit; Prkaca = cyclic AMP-dependent protein kinase catalytic subunit)

  3. K8/K18 (show KRT18 Antibodies)-dependent PKCdelta- and ASMase (show SMPD1 Antibodies)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (show KRT18 Antibodies) loss.

  4. MALAT1 recruits splice factor serine-arginine-rich splice factor 2 (SRSF2 (show SRSF2 Antibodies)) to promote alternative splicing of PKCdeltaII.

  5. cAMP dependent protein kinase A (PKA) is a key intracellular factor mediating SHH (show SHH Antibodies) signaling through regulation of GLI3 (show GLI3 Antibodies) processing.

  6. this study shows illustrates for the first time the ability of protein kinase A to increase colony-stimulating factor 1 receptor (show CSF1R Antibodies) DNA methylation (show HELLS Antibodies) resulting in macrophage maturation

  7. these results suggest that the activation of 5-HT1D receptors selectively enhanced IA via the Gbetagamma of the Go-protein, PKA, and the sequential B-Raf (show SNRPE Antibodies)-dependent p38 MAPK (show MAPK14 Antibodies) signaling cascade.

  8. SphK1 (show SPHK1 Antibodies) dependent PKC-delta activation plays an important role in promoting NF-kappaB (show NFKB1 Antibodies) activation and inflammatory response in acute liver failure, and inhibition of PKC-delta activation might be a potential therapeutic strategy for this disease.

  9. PKCdelta activity exerts a dual role through the autophagy mechanism, decreasing proliferative capacity of mammary tumor cells but also regulating tumor stem cell self-renewal.

  10. alpha(1)-AR activation is anti-apoptotic and protective during cardiac ischemia due to glucose deprivation and not hypoxia by enhancing glucose uptake into the heart via PKCdelta-mediated GLUT (show SLC1A3 Antibodies) translocation that may be specific to the alpha(1A)-AR subtype.

Cow (Bovine) Protein Kinase C, delta (PKCd) interaction partners

  1. Report PRKCD-dependent regulation of bovine embryonic development, gene expression and post-hatching events.

  2. investigation of signaling mechanism used by fibroblast growth factor-2 (FGF2 (show FGF2 Antibodies)) to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 (show FGF2 Antibodies) regulates IFNT production in trophoblasts by acting through PRKCD

  3. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (show NOS3 Antibodies) post-translational modification

  4. stimulation of bovine theca cells with lysophosphatidic acid leads to redistribution of protein kinase C delta from the cytosol to the perinuclear area and in the presence of LH, complete nuclear translocation of protein kinase C delta is induced

  5. Protein kinase (show CDK7 Antibodies) Cdelta-dependent phosphorylation of syndecan-4 (show SDC4 Antibodies) regulates cell migration.

Rabbit Protein Kinase C, delta (PKCd) interaction partners

  1. Activation of PKC (show PKC Antibodies) induces the translocation of Nrf2 (show NFE2L2 Antibodies) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. PKC-delta (show PRKCG Antibodies) mediates the apoptotic processes through ROS (show ROS1 Antibodies)-dependent caspase-3 (show CASP3 Antibodies) activation

PKC delta (PKCd) Antigen Profile

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with PKC delta (PKCd)

  • protein kinase C, delta a (prkcda) antibody
  • protein kinase C, delta (prkcd-b) antibody
  • protein kinase C, delta (prkcd) antibody
  • protein kinase C, delta (LOC100230711) antibody
  • protein kinase C, delta (PRKCD) antibody
  • protein kinase C, delta (Prkcd) antibody
  • protein kinase, cAMP dependent, catalytic, alpha (Prkaca) antibody
  • AI385711 antibody
  • D14Ertd420e antibody
  • fb09d10 antibody
  • fv43b11 antibody
  • MAY1 antibody
  • nPKC-delta antibody
  • Pkaca antibody
  • PKC-delta antibody
  • pkc-delta2 antibody
  • Pkcd antibody
  • PKCdelta antibody
  • PKC[d] antibody
  • PRKCD antibody
  • tpa-1 antibody
  • wu:fb09d10 antibody
  • wu:fv43b11 antibody
  • zgc:56558 antibody

Protein level used designations for PKCd

protein kinase C delta type , protein kinase-delta2 , protein kinase C, delta , protein kinase C delta type-like , protein kinase C delta VIII , tyrosine-protein kinase PRKCD , nPKC-delta , protein kinase C delta variant IX , protein kinase C, delta IV , protein kinase C, delta V , protein kinase C[d] , protein kinase C delta , PKA C-alpha , cAMP-dependent protein kinase catalytic subunit alpha , sperm cAMP-dependent protein kinase catalytic subunit

GENE ID SPECIES
334571 Danio rerio
404227 Xenopus laevis
733756 Xenopus (Silurana) tropicalis
100230711 Taeniopygia guttata
100294651 Ovis aries
100395399 Callithrix jacchus
100452668 Pongo abelii
100591028 Nomascus leucogenys
5580 Homo sapiens
18753 Mus musculus
170538 Rattus norvegicus
505708 Bos taurus
100008966 Oryctolagus cuniculus
100126848 Sus scrofa
494005 Canis lupus familiaris
415905 Gallus gallus
101107639 Ovis aries
18747 Mus musculus
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