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anti-Rat (Rattus) PKC delta antibody for Immunoprecipitation

Recommended PKC delta Antibody (supplied by: Log in to see )

Antigen
Protein Kinase C, delta (PKCd) Antibodies
  • AI385711
  • D14Ertd420e
  • fb09d10
  • fv43b11
  • MAY1
  • may1
  • npkc-delta
  • nPKC-delta
  • Pkaca
  • PKC-delta
  • pkc-delta2
  • pkcd
  • Pkcd
  • PKCD
  • PKCdelta
  • PKC[d]
  • prkcd
  • PRKCD
  • tpa-1
  • wu:fb09d10
  • wu:fv43b11
  • zgc:56558
Epitope
AA 114-289
40
33
24
22
15
13
12
11
10
8
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
256
144
124
7
2
2
2
2
2
1
Host
Mouse
267
18
Clonality
Monoclonal
Conjugate
This PKC delta antibody is un-conjugated
9
9
7
4
4
4
3
3
3
3
3
3
3
3
3
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
225
128
103
36
35
26
10
10
6
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN967942
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008957968 ABIN967943 IF IP IHC WB Mouse IgG2b AA 114-289 Log in to see 14-PKC delta 5
0.0008957968 ABIN870319 IP ELISA WB Rabbit Log in to see K15-K
0.0008957968 ABIN870318 IP ELISA WB Rabbit Log in to see K15-K
0.0008957968 ABIN4345831 ELISA IHC IHC (fro) IHC (p) IP WB Rabbit IgG Log in to see K15-K

Top referenced anti-PKC delta antibody for Immunoprecipitation

Similar anti-PKC delta Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 45 Antibodies 56 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 4 Antibodies
Immunofluorescence (IF) 21 Antibodies 19 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies 34 Antibodies
Immunohistochemistry (IHC) 45 Antibodies 46 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 20 Antibodies 20 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 87 Antibodies

General

Antigen Protein Kinase C, delta (PKCd) Antibodies
Epitope AA 114-289
(40), (33), (24), (22), (15), (13), (12), (11), (10), (8), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(256), (144), (124), (7), (2), (2), (2), (2), (2), (1)
Host Mouse
(267), (18)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PKC delta antibody is un-conjugated
(9), (9), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(225), (128), (103), (36), (35), (26), (10), (10), (6), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-PKC delta Antibody

Target Details PKC delta Application Details Handling References for anti-PKC delta Antibody (ABIN967942) Images
Cross-Reactivity Rat (Rattus), Mouse (Murine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human PKCdelta aa. 114-289
Clone 14-PKC delta
Isotype IgG2b

Target Details PKC delta

Product Details anti-PKC delta Antibody Application Details Handling References for anti-PKC delta Antibody (ABIN967942) Images back to top
Antigen
Alternative Name PKC delta (PKCd Antibody Abstract)
Background The Protein Kinase C (PKC) family of homologous serine/threonine protein kinases. At least eleven isozymes have been described. These proteins are products of multiple genes and alternative splicing. PKC consists of a single polypeptide chain containing four conserved regions (C) and five variable regions (V). The N-terminal half containing C1, C2, V1, and V2 constitutes the regulatory domain and interacts with PKC activators Ca2+, phospholipid, diacylglycerol, or phorbol ester. However, the novel PKC (nPKC) subfamily members (delta, epsilon, eta, and theta isoforms) and the atypical PKC (aPKC) subfamily members (zeta, iota, and lambda isoforms) are Ca2+ independent and lack the C2 domain. The aPKC members are unique in that their activity is independent of diacylglycerols and phorbol esters. They also lack one repeat of the cysteine-rich sequences that are conserved in cPKC and nPKC. The C-terminal region of PKC contains the catalytic domain. PKCdelta is involved in myeloid differentiation, as well as in the secretory response of antigen-stimulated rat basophilic RBL 2H3 cells. Overexpression and subsequent stimulation of PKCdelta leads to cell cycle arrest in CHO cells and complete growth inhibition of NIH 3T3 cells. PKCdelta is the most abundant isoform in hemopoietic cells and is highly expressed in many other organs and tissues. This suggests that PKCdelta may be one of the major PKC isozymes in mammalian cells.
Molecular Weight 78 kDa
Research Area Cancer, Signaling, Protein Modifications, Kinases/Phosphatases
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PKC delta Antibody Target Details PKC delta Handling References for anti-PKC delta Antibody (ABIN967942) Images back to top
Comment

Related Products: ABIN968545

Restrictions For Research Use only

Handling

Product Details anti-PKC delta Antibody Target Details PKC delta Application Details References for anti-PKC delta Antibody (ABIN967942) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-PKC delta Antibody (ABIN967942)

Product Details anti-PKC delta Antibody Target Details PKC delta Application Details Handling Images back to top
Product cited in:

Larsen, Ueyama, Brannock, Shirai, Saito, Larsson, Loegering, Weber, Lennartz: "A role for PKC-epsilon in Fc gammaR-mediated phagocytosis by RAW 264.7 cells." in: The Journal of cell biology, Vol. 159, Issue 6, pp. 939-44, 2002

Ringshausen, Schneller, Bogner, Hipp, Duyster, Peschel, Decker: "Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta." in: Blood, Vol. 100, Issue 10, pp. 3741-8, 2002

Blass, Kronfeld, Kazimirsky, Blumberg, Brodie: "Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide." in: Molecular and cellular biology, Vol. 22, Issue 1, pp. 182-95, 2001

Bell, Burns: "Lipid activation of protein kinase C." in: The Journal of biological chemistry, Vol. 266, Issue 8, pp. 4661-4, 1991

Nishizuka: "The molecular heterogeneity of protein kinase C and its implications for cellular regulation." in: Nature, Vol. 334, Issue 6184, pp. 661-5, 1988

Images

Product Details anti-PKC delta Antibody Target Details PKC delta Application Details Handling References for anti-PKC delta Antibody (ABIN967942) back to top
Supplier Images
Western Blotting (WB) image for anti-PKC delta antibody (Protein Kinase C, delta) (AA 114-289) (ABIN967942) Western blot analysis of PKCdelta on rat brain lysate. Lane 1: 1:500, lane 2: 1:1000,...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PKC delta antibody (Protein Kinase C, delta) (AA 114-289) (ABIN967942) Rat brain zinc-fixed paraffin-embedded tissue
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PKC delta antibody (Protein Kinase C, delta) (AA 114-289) (ABIN967942) Purkinje Cells in rat cerebellum, formalin-fixed paraffin-embedded tissue, citrate pr...