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Browse our anti-PKC theta (PRKCQ) Antibodies

Full name:
anti-Protein Kinase C, theta Antibodies (PRKCQ)
On www.antibodies-online.com are 214 Protein Kinase C, theta (PRKCQ) Antibodies from 23 different suppliers available. Additionally we are shipping PKC theta Kits (36) and PKC theta Proteins (7) and many more products for this protein. A total of 267 PKC theta products are currently listed.
Synonyms:
A130035A12Rik, AW494342, nPKC-theta, PKC-0, PKC-theta, Pkcq, PKCtheta, PRKCT
list all antibodies Gene Name GeneID UniProt
PRKCQ 5588 Q04759
PRKCQ 18761 Q02111
PRKCQ 85420  

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Most Popular Reactivities for anti-PKC theta (PRKCQ) Antibodies

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anti-Human PKC theta Antibodies:

anti-Mouse (Murine) PKC theta Antibodies:

anti-Rat (Rattus) PKC theta Antibodies:

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Top referenced anti-PKC theta Antibodies

  1. Human Polyclonal PKC theta Primary Antibody for EIA, IHC (p) - ABIN359074 : Carrasco, Merida: Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. in Molecular biology of the cell 2004 (PubMed)
    Show all 5 references for ABIN359074

  2. Human Monoclonal PKC theta Primary Antibody for IHC (f), IF - ABIN967738 : Dienz, Hehner, Droge, Schmitz: Synergistic activation of NF-kappa B by functional cooperation between vav and PKCtheta in T lymphocytes. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN967738

  3. Human Polyclonal PKC theta Primary Antibody for IF, IHC (p) - ABIN197566 : Van Kolen, Slegers: Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. in The FEBS journal 2006 (PubMed)
    Show all 3 references for ABIN197566

  4. Human Polyclonal PKC theta Primary Antibody for IF, IHC (p) - ABIN197070 : Villalba, Bi, Hu, Altman, Bushway, Reits, Neefjes, Baier, Abraham, Altman: Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C. in The Journal of cell biology 2002 (PubMed)
    Show all 3 references for ABIN197070

  5. Human Monoclonal PKC theta Primary Antibody for IHC (f), WB - ABIN968924 : Nishizuka: The molecular heterogeneity of protein kinase C and its implications for cellular regulation. in Nature 1988 (PubMed)
    Show all 2 references for ABIN968924

  6. Human Polyclonal PKC theta Primary Antibody for IHC (p) - ABIN196902 : Xu, Chaudhary, Olland, Wolfrom, Czerwinski, Malakian, Lin, Stahl, Joseph-McCarthy, Benander, Fitz, Greco, Somers, Mosyak: Catalytic domain crystal structure of protein kinase C-theta (PKCtheta). in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN196902

  7. Human Polyclonal PKC theta Primary Antibody for IHC (p), WB - ABIN197400 : Thebault, Ochoa-Garay: Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes. in Molecular immunology 2004 (PubMed)
    Show all 2 references for ABIN197400

  8. Human Monoclonal PKC theta Primary Antibody for WB - ABIN968923 : Soderling: Protein kinases. Regulation by autoinhibitory domains. in The Journal of biological chemistry 1990 (PubMed)
    Show all 2 references for ABIN968923

  9. Human Polyclonal PKC theta Primary Antibody for IHC, ELISA - ABIN1531465 : Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: The DNA sequence and comparative analysis of human chromosome 10. ... in Nature 2004 (PubMed)

More Antibodies against PKC theta Interaction Partners

Pig (Porcine) Protein Kinase C, theta (PRKCQ) interaction partners

  1. The results indicate that PKC (show FYN Antibodies) could be the final target and an integrator molecule of different signaling pathways triggered by angiotensin II (Ang II), which could explain the sustained activation of Na(+)-ATPase (show DNAH8 Antibodies) by Ang II (show AGT Antibodies).

  2. Phorbol 12-myristate 13-acetate activation of ERK (show MAPK1 Antibodies) and JNK (show MAPK8 Antibodies) signaling is relevant in the regulation of gene expression during follicular development, ovulation, and luteinization.

Human Protein Kinase C, theta (PRKCQ) interaction partners

  1. Data show that tonantzitlolone (TZL) was able to induce protein kinase c theta (PKCtheta;)-dependent heat shock transcription factor 1 (HSF1 (show HSF1 Antibodies))phosphorylation.

  2. The PRKCQ polymorphism is not associated with Behcet's Disease.

  3. Sumoylation of PKC-theta; was essential for T cell activation. Desumoylation did not affect the catalytic activity of PKC-theta; but inhibited the association of CD28 (show CD28 Antibodies) with PKC-theta; and filamin A (show FLNA Antibodies) and impaired the assembly of a mature immunological synapse.

  4. Together, these findings both in Jurkat T cells as well as in primary T cells indicate a regulatory role of Coro1A (show CORO1A Antibodies) on PKCtheta; recruitment and function downstream of the TCR leading to NF-kappaB (show NFKB1 Antibodies) transactivation.

  5. PKCtheta; acts through the activation of p38 MAPK (show MAPK14 Antibodies) and autophagy induction. PKCtheta; acts through the activation of p38 MAPK (show MAPK14 Antibodies) and autophagy induction to induce the Epstein-Barr virus (EBV) lytic cycle.

  6. Data suggest that protein kinase C theta (PKCtheta;) inhibition alone may be sufficient to drive efficacy in chronic autoimmune and inflammatory diseases.

  7. responsive to chemokine (show CCL1 Antibodies) induced migration and are defective in migration to lymph nodes. Our results reveal a novel role for PKCtheta; in regulating T cell migration

  8. protein kinase C-theta promotes Epithelial to mesenchymal transition by acting as a critical chromatin-anchored switch for inducible genes via transforming growth factor beta and the key inflammatory regulatory protein NF-kappaB (show NFKB1 Antibodies).

  9. Diacylglycerol activation of protein kinase (show CDK7 Antibodies) Ctheta; and subsequent impairment of insulin (show INS Antibodies) signaling plays a major role in the pathogenesis of muscle insulin (show INS Antibodies) resistance in humans.

  10. The results show that PKC-theta; has important diagnostic significance in gastrointestinal stromal tumors.

Mouse (Murine) Protein Kinase C, theta (PRKCQ) interaction partners

  1. Sumoylation of PKC-theta; was essential for T cell activation. Desumoylation did not affect the catalytic activity of PKC-theta; but inhibited the association of CD28 (show CD28 Antibodies) with PKC-theta; and filamin A (show FLNA Antibodies) and impaired the assembly of a mature immunological synapse.

  2. Together, these findings both in Jurkat T cells as well as in primary T cells indicate a regulatory role of Coro1A (show CORO1A Antibodies) on PKCtheta; recruitment and function downstream of the TCR leading to NF-kappaB (show NFKB1 Antibodies) transactivation.

  3. Knockdown of PKCtheta suppresses phosphorylation of IKK (show CHUK Antibodies) and JNK (show MAPK8 Antibodies) and consequently attenuates the HOCl-impaired insulin (show INS Antibodies) signaling pathway.

  4. Data indicate that Protein kinase C theta; (PKCtheta;) is critical for stabilizing Th17 cell phenotype.

  5. Data suggest that protein kinase (show CDK7 Antibodies) Ctheta (PKCtheta;) inhibition alone is insufficient for complete efficacy in rodent arthritis model.

  6. Inhibition of PKC-theta preserves cardiac function and reduces fibrosis in streptozotocin-induced diabetic cardiomyopathy

  7. DTX1, similar to Cbl-b and Itch, participates in T cell anergy-induced PKC-theta degradation. there is a coupling of DTX1 to Cbl-b in T cell anergy.

  8. Therefore, TCR ligation elicits a caspase (show CASP3 Antibodies) cascade involving caspase-8 (show CASP8 Antibodies), caspase-9 (show CASP9 Antibodies) and caspase-3 (show CASP3 Antibodies) which initiates PKC-theta;-dependent pathway leading to NF-kappaB (show NFKB1 Antibodies) activation.

  9. PKCtheta regulates myogenic and protein synthetic signaling via the modulation of IRS1 (show IRS1 Antibodies) and ERK1 (show MAPK3 Antibodies)/ERK2 (show MAPK1 Antibodies) phosphorylation.

  10. timed activation of PKCtheta;, phosphorylation of EKLF at S68 by P-PKCtheta;(S676), and sumoylation of EKLF at K74 occurs during the Pro-E to Baso-E transition

PKC theta (PRKCQ) Antigen Profile

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Alternative names and synonyms associated with PKC theta (PRKCQ)

  • protein kinase C, theta (PRKCQ) antibody
  • protein kinase C theta (PKC) antibody
  • protein kinase C, theta (Prkcq) antibody
  • A130035A12Rik antibody
  • AW494342 antibody
  • nPKC-theta antibody
  • PKC-0 antibody
  • PKC-theta antibody
  • Pkcq antibody
  • PKCtheta antibody
  • PRKCT antibody

Protein level used designations for PRKCQ

protein kinase C theta type , PKC theta , nPKC-theta

GENE ID SPECIES
100070207 Equus caballus
100152637 Sus scrofa
5588 Homo sapiens
18761 Mus musculus
85420 Rattus norvegicus
478013 Canis lupus familiaris
505901 Bos taurus
776459 Gallus gallus
100726308 Cavia porcellus
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