Browse our anti-PTEN (PTEN) Antibodies

Full name:
anti-Phosphatase and Tensin Homolog Antibodies (PTEN)
On www.antibodies-online.com are 0 Phosphatase and Tensin Homolog (PTEN) Antibodies from different suppliers available. A total of 0 PTEN products are currently listed.
Synonyms:
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

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More Antibodies against PTEN Interaction Partners

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. these results demonstrate that miR (show MLXIP Antibodies)-26b might participate in regulating adipogenic differentiation in 3T3-L1 cells by inhibiting the PTEN expression, further highlighting the importance of miRNA in adipogenesis.

  2. Studies indicate complex PTEN-cooperating tumor suppressor networks in different cancer types, with potential clinical implications.

  3. Studies indicate that progesterone receptor (show PGR Antibodies) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (show CXCL9 Antibodies)-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (show MAPK1/3 Antibodies) and its target genes.

  4. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (show AKT1 Antibodies) pathway.

  5. Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten on MUC1 (show MUC1 Antibodies) and EMT (show ITK Antibodies) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten deletions and MUC1 (show MUC1 Antibodies) vaccines.

  6. novel role for PTEN during infection and identify regulation of the PI3K pathway, a mechanism previously shown to silence autoreactive B cells, as a key physiological target to control antibody responses.

  7. This study demonstrated Pten Regulates Retinal Amacrine Cell Number by Modulating Akt (show AKT1 Antibodies), Tgfbeta (show TGFB1 Antibodies), and Erk (show EPHB2 Antibodies) Signaling in mice.

  8. Tregs ameliorated ICH (show ACE Antibodies)-induced inflammatory injury by modulating microglia/macrophage polarization toward the M2 phenotype through the IL-10 (show IL10 Antibodies)/GSK3beta (show GSK3b Antibodies)/PTEN axis

  9. Data show that macrophage M2 polarization was mediated through PTEN/PI3k/AKT (show AKT1 Antibodies) pathway activation.

  10. this study shows this study shows that infection-induced miR (show MLXIP Antibodies)-21 promotes severe, steroid-insensitive allergic airway disease by reducing PTEN expression

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN rs701848 and AKT1 (show AKT1 Antibodies) rs2494752 polymorphisms might be a candidate pharmacogenomic factor to assess the susceptibility of and response and prognosis prediction for interindividualized CE(A)F chemotherapy in breast cancer patients.

  2. Meta-analysis demonstrates that PTEN loss is of particular importance for predicting breast cancer aggressiveness and poor prognosis. PTEN is a potential drug target for the development of individualized treatment in breast cancer patients.

  3. PTENp1 was aberrantly expressed in oral squamous cell carcinoma. There was a positive correlation between the expression levels of PTENp1 and PTEN. Further, we showed that PTENp1 acted as a competing endogenous RNA that protects PTEN transcripts from being inhibited by miR (show MLXIP Antibodies)-21, and consequently inhibited proliferation and colony formation and triggered S-G2 (show STRN3 Antibodies)/M cell cycle arrest through the AKT (show AKT1 Antibodies) pathway.

  4. Results indicate that p110alpha (show PIK3CA Antibodies) primarily mediates PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling in HER2 (show ERBB2 Antibodies)+ PTEN deficient breast tumors whereas p110beta conditionally mediates HER2 (show ERBB2 Antibodies)/PI3K (show PIK3CA Antibodies) signaling in the absence of p110alpha (show PIK3CA Antibodies).

  5. Her-2 (show ERBB2 Antibodies)-positive metastatic breast cancers, PTEN positivity was significantly associated with progressive disease, but not with PFS or OS

  6. Findings indicate that Epstein-Barr virus(EBV)-encoded latent membrane protein 1 (LMP1 (show PDLIM7 Antibodies)), PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies), miR (show MLXIP Antibodies)-21 and PTEN constitute a positive feedback loop and have a key role in LMP1 (show PDLIM7 Antibodies)-induced cancer stem cells (CSCs) in nasopharyngeal carcinoma (NPC (show NPC1 Antibodies)).

  7. Coexpression of SALL4 (show SALL4 Antibodies) with HDAC1 (show HDAC1 Antibodies) and/or HDAC2 (show HDAC2 Antibodies) was associated with PTEN underexpression and a poor prognosis in hepatocellular carcinoma.

  8. PTEN promoter methylation is an independent predictor for impaired survival with malignant melanoma.

  9. Studies indicate that frequently altered genes in type I carcinomas are TP53, K-Ras, PTEN, and ss-catenin.

  10. Study provide evidence that PTEN deletion and TMPRSS2 (show TMPRSS2 Antibodies)-ERG (show ERG Antibodies) gene fusion were mutually exclusive in patients with prostate neoplasm. TMPRSS2 (show TMPRSS2 Antibodies)-ERG (show ERG Antibodies) gene fusion was rare compared to peripheral zone tumors and to PTEN inactivation in T1a (show PDPN Antibodies) transition zone tumors.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (show FOXO3 Antibodies) and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (show BMPR2 Antibodies) genes.

  2. miR (show MYLIP Antibodies)-26b participates in the inflammatory response of LPS (show IRF6 Antibodies)-stimulated bAMs by modulating the NF-kappaB (show NFKB1 Antibodies) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (show NOS3 Antibodies) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (show DVL2 Antibodies).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen Profile

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) antibody
  • phosphatase and tensin homolog (PTEN) antibody
  • phosphatase and tensin homolog (pten) antibody
  • 10q23del antibody
  • 2310035O07Rik antibody
  • A130070J02Rik antibody
  • AI463227 antibody
  • B430203M17Rik antibody
  • BZS antibody
  • CWS1 antibody
  • DEC antibody
  • GLM2 antibody
  • MHAM antibody
  • Mmac antibody
  • MMAC1 antibody
  • PTEN1 antibody
  • PTENP1 antibody
  • TEP1 antibody

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

GENE ID SPECIES
19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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