anti-Rat (Rattus) RIPK2 antibody for Enzyme Immunoassay

Recommended RIPK2 Antibody (supplied by: Log in to see )

Antigen
Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
  • RIPK2
  • 2210420D18Rik
  • CARD3
  • CARDIAK
  • CCK
  • D4Bwg0615e
  • RICK
  • RIP2
  • GIG30
  • receptor-interacting serine-threonine kinase 2
  • receptor (TNFRSF)-interacting serine-threonine kinase 2
  • RIPK2
  • LOC100223072
  • Ripk2
Epitope
N-Term
28
12
9
8
7
5
5
5
5
5
3
3
3
2
2
2
2
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
144
55
32
6
5
5
4
4
3
2
1
Host
Rabbit
125
16
5
Clonality
Polyclonal
Conjugate
This RIPK2 antibody is un-conjugated
6
6
4
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
134
70
47
23
21
19
7
3
2
2
1
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Catalog No. ABIN5555171
$ 375.38
Plus shipping costs $45.00

General

Antigen Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) Antibodies
Epitope N-Term
(28), (12), (9), (8), (7), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(144), (55), (32), (6), (5), (5), (4), (4), (3), (2), (1)
Host Rabbit
(125), (16), (5)
Clonality
Polyclonal
Conjugate This RIPK2 antibody is un-conjugated
(6), (6), (4), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(134), (70), (47), (23), (21), (19), (7), (3), (2), (2), (1)
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Product Details anti-RIPK2 Antibody

Target Details RIPK2 Application Details Handling Images
Specificity This antibody detects RICK at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogen RICK antibody was raised against a peptide corresponding to amino acids near the amino terminus of human RICK.
Isotype IgG

Target Details RIPK2

Product Details anti-RIPK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name RIPK2 (RIPK2 Antibody Abstract)
Background Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively, (1-3). RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1b. The messenger RNA of RICK is expressed in multiple human tissues.Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2
Gene ID 8767
UniProt O43353
Research Area Apoptosis/Necrosis, Signaling
Pathways TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades

Application Details

Product Details anti-RIPK2 Antibody Target Details RIPK2 Handling Images back to top
Application Notes ELISA. Western blot: 1: 1000, an approximately 60 kDa band can be detected. Immuoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RIPK2 Antibody Target Details RIPK2 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.