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Browse our anti-VAV1 (VAV1) Antibodies

Full name:
anti-Vav 1 Oncogene Antibodies (VAV1)
On are 138 Vav 1 Oncogene (VAV1) Antibodies from 19 different suppliers available. Additionally we are shipping VAV1 Kits (5) and VAV1 Proteins (5) and many more products for this protein. A total of 152 VAV1 products are currently listed.
Vav, vav-T
list all antibodies Gene Name GeneID UniProt
VAV1 7409 P15498
VAV1 25156  
VAV1 22324 P27870

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Most Popular Reactivities for anti-VAV1 (VAV1) Antibodies

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anti-Human VAV1 Antibodies:

anti-Rat (Rattus) VAV1 Antibodies:

anti-Mouse (Murine) VAV1 Antibodies:

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Top referenced anti-VAV1 Antibodies

  1. Human Polyclonal VAV1 Primary Antibody for WB - ABIN265200 : Moores, Selfors, Fredericks, Breit, Fujikawa, Alt, Brugge, Swat: Vav family proteins couple to diverse cell surface receptors. in Molecular and cellular biology 2000 (PubMed)
    Show all 7 references for ABIN265200

  2. Human Monoclonal VAV1 Primary Antibody for IF, WB - ABIN394203 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN394203

  3. Human Polyclonal VAV1 Primary Antibody for WB - ABIN196856 : Amarasinghe, Rosen: Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. in Biochemistry 2005 (PubMed)
    Show all 4 references for ABIN196856

  4. Human Polyclonal VAV1 Primary Antibody for WB - ABIN197374 : Charvet, Canonigo, Billadeau, Altman: Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for ABIN197374

  5. Human Polyclonal VAV1 Primary Antibody for WB - ABIN657774 : Barda-Saad, Shirasu, Pauker, Hassan, Perl, Balbo, Yamaguchi, Houtman, Appella, Schuck, Samelson: Cooperative interactions at the SLP-76 complex are critical for actin polymerization. in The EMBO journal 2010 (PubMed)
    Show all 2 references for ABIN657774

  6. Human Monoclonal VAV1 Primary Antibody for FACS, ELISA - ABIN969581 : Bertagnolo, Nika, Brugnoli, Bonora, Grassilli, Pinton, Capitani: Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells. in Cell and tissue research 2011 (PubMed)
    Show all 2 references for ABIN969581

  7. Human Polyclonal VAV1 Primary Antibody for IF, ELISA - ABIN1532426 : Ramos-Morales, Romero, Schweighoffer, Bismuth, Camonis, Tortolero, Fischer: The proline-rich region of Vav binds to Grb2 and Grb3-3. in Oncogene 1995 (PubMed)

  8. Cow (Bovine) Polyclonal VAV1 Primary Antibody for WB - ABIN2792554 : Schneider, Rudd: CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against VAV1 Interaction Partners

Human Vav 1 Oncogene (VAV1) interaction partners

  1. revealed a new function for Vav1 in the negative feedback regulation of the phosphorylation of immunoreceptor tyrosine-based activation motifs within the zeta chains, CD3 delta (show CD3D Antibodies), epsilon, gamma chains, as well as activation sites on the critical T cell tyrosine kinases

  2. Data indicate that only a single mutation in the proto-oncogene (show RAB1A Antibodies) Vav1 enhances tumorigenicity.

  3. These findings establish VAV1 as a critical epigenetically regulated oncogene (show RAB1A Antibodies) with a key role in MBSHH maintenance, and highlight its potential as a validated therapeutic target and prognostic biomarker for the improved therapy of medulloblastoma.

  4. The present study implies that estrogen-estrogen receptor (show ESR1 Antibodies) modulates the transcription and expression of Vav1, which may contribute to the proliferation of cancerous cells.

  5. The role of Vav1 in T leukemia survival by selectively triggering Rac2 (show RAC2 Antibodies)-Akt (show AKT1 Antibodies) axis and elevating the expression of anti-apoptotic Bcl-2 (show BCL2 Antibodies).

  6. results presented herein suggest a potential cross-talk between cancer cells and the microenvironment controlled by CSF1 (show CSF1 Antibodies)/Vav1 signaling pathways.

  7. our data provide evidence that Vav1 is the linker molecule that couples CD28 to PIP5Kalpha activation and strongly fit with a potential model in which CD28 regulates PIP2 synthesis and turnover in T lymphocytes.

  8. suggest that Vav1 promotes the matrix-degrading processes underlying tumor cell migration and further, under conditions of ectopic Vav1 expression, that Vav1 is a central regulator and major driver of invasive matrix remodeling by pancreatic tumor cells

  9. VAV1 overexpression in both SKOV3 and human ovarian surface epithelial cells demonstrated that its upregulation of an E-cadherin (show CDH1 Antibodies) transcriptional repressor, Snail (show SNAI1 Antibodies) and Slug (show SNAI2 Antibodies), was not confined to ovarian cancer cells

  10. The results highlight for the first time the potential role of Vav1 as an oncogenic stress activator in cancer and the p53 (show TP53 Antibodies) dependence of its pro-apoptotic effect in breast cells.

Mouse (Murine) Vav 1 Oncogene (VAV1) interaction partners

  1. provide evidence that CD28 (show CD28 Antibodies) and the TCR complex regulate NF-kappaB (show NFKB1 Antibodies) via different signaling modules of GRB-2 (show GRB2 Antibodies)/VAV1 and LAT (show LAT Antibodies)/ADAP (show APP Antibodies) pathways respectively.

  2. Platelet P-Rex and Vav family Rac (show AKT1 Antibodies)-GEFs play important proinflammatory roles in leukocyte recruitment.

  3. The data show that vav1 not only affects transcription of the MHCII locus but also is an important regulator of MHCII protein transport to the cell surface.

  4. analyses revealed a SHP2 (show PTPN11 Antibodies)- and Lyn (show LYN Antibodies)-dependent pathway leading to phosphorylation of Vav1, Rac (show AKT1 Antibodies) activation, and F-actin polymerization in SCF (show KITLG Antibodies)-treated BMMCs

  5. Data indicate that Vav1 was a key negative regulator of macrophage-derived IL-6 (show IL6 Antibodies) production.

  6. Bruton's Tyrosine Kinase (BTK (show BTK Antibodies)) and Vav1 contribute to Dectin1 (show CLEC7A Antibodies)-dependent phagocytosis of Candida albicans in macrophages.

  7. Suggest that Vav1 act as critical molecular link coupling hyperlipidemia with proatherogenic monocyte/macrophage responses.

  8. Loss of Vav1 activity does not favour development of colitis-associated colon cancer.

  9. SH2 and SH3(B) domains of Vav1 are critical for the phosphorylation of Vav1 and its signalling function in TCR-induced calcium flux.

  10. SAP (show APCS Antibodies) couples SLAM (show SLAMF1 Antibodies) family receptors to the kinase Fyn (show FYN Antibodies), which triggered the exchange factor Vav-1 and augmented NK cell activation.

VAV1 Antigen Profile

Antigen Summary

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with VAV1

  • vav 1 guanine nucleotide exchange factor (VAV1) antibody
  • vav 1 guanine nucleotide exchange factor (Vav1) antibody
  • vav 1 oncogene (Vav1) antibody
  • vav 1 oncogene (vav1) antibody
  • Vav antibody
  • vav-T antibody

Protein level used designations for anti-Vav 1 Oncogene (VAV1) Antibodies

vav 1 oncogene , proto-oncogene vav , p95 , p95vav , vav oncogene

455647 Pan troglodytes
7409 Homo sapiens
25156 Rattus norvegicus
485016 Canis lupus familiaris
617345 Bos taurus
100519821 Sus scrofa
22324 Mus musculus
446826 Xenopus laevis
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