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anti-Cow (Bovine) VAV1 antibody for Western Blotting

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
Epitope
Middle Region
34
21
19
15
13
11
5
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
137
62
60
Host
Rabbit
124
13
Clonality
Polyclonal
Conjugate
This VAV1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
115
56
23
12
9
8
6
3
1
1
1
Supplier
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Catalog No. ABIN2792554
$ 289.00
Plus shipping costs $45.00

Top referenced anti-VAV1 antibody for Western Blotting

Similar anti-VAV1 Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine) Cow (Bovine) Dog (Canine) Xenopus laevis
Western Blotting (WB) 119 Antibodies 47 Antibodies 46 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies 7 Antibodies 6 Antibodies
Immunohistochemistry (IHC) 25 Antibodies 15 Antibodies 14 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies 12 Antibodies

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Epitope Middle Region
(34), (21), (19), (15), (13), (11), (5), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(137), (62), (60)
Host Rabbit
(124), (13)
Clonality
Polyclonal
Conjugate This VAV1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(115), (56), (23), (12), (9), (8), (6), (3), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling References for anti-VAV1 Antibody (ABIN2792554) Images
Sequence RDRSELSLKE GDIIKILNKK GQQGWWRGEI YGRVGWFPAN YVEEDYSEYC
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Predicted Reactivity Human : 100 %, Bovine : 90 %, Dog : 90 %, Horse : 90 %, Mouse : 90 %, Pig : 90 %, Rat : 90 %, Rabbit : 90 %, African clawed frog : 80 %
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human VAV1

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling References for anti-VAV1 Antibody (ABIN2792554) Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background This protein is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
Molecular Weight 98 kDa
Gene ID 7409
NCBI Accession NP_005419, NM_005428
UniProt P15498
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling References for anti-VAV1 Antibody (ABIN2792554) Images back to top
Application Notes WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 845 AA

Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details References for anti-VAV1 Antibody (ABIN2792554) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-VAV1 Antibody (ABIN2792554)

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling Images back to top
Background publications

Schneider, Rudd: "CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 616-21, 2008

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling References for anti-VAV1 Antibody (ABIN2792554) back to top
Supplier Images
Western Blotting (WB) image for anti-VAV1 antibody (Vav 1 Oncogene) (Middle Region) (ABIN2792554) WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...