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anti-Human VAV1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
Reactivity
Human, Mouse (Murine), Rat (Rattus)
137
62
60
1
1
1
Host
Rabbit
124
13
Clonality
Polyclonal
Conjugate
This VAV1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
115
56
23
12
9
7
6
3
1
1
1
Supplier
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Catalog No. ABIN271858
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN2855640 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
0.00089488085 ABIN711866 IF (p) IHC (p) WB Rabbit IgG AA 150-165, pTyr160 Log in to see Polyclonal
0.00089488085 ABIN711868 IHC (p) WB Biotin Rabbit IgG AA 150-165, pTyr160 Log in to see Polyclonal
0.00089488085 ABIN711875 IHC (p) WB HRP Rabbit IgG AA 150-165, pTyr160 Log in to see Polyclonal
0.00089488085 ABIN408510 IHC (p) IHC WB Rabbit IgG Tyr174 Log in to see Polyclonal
0.00089488085 ABIN1947670 IHC (p) WB Rabbit IgG AA 83-568 Log in to see Polyclonal
0.00089488085 ABIN711881 IF (p) IHC (p) WB Rabbit IgG pTyr174 Log in to see Polyclonal
0.00089488085 ABIN441430 IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN2799912 IHC (f) IHC (p) IHC WB Rabbit IgG AA 83-568 Log in to see Polyclonal

Similar anti-VAV1 Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine)
Western Blotting (WB) 119 Antibodies 47 Antibodies 46 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies 7 Antibodies 6 Antibodies
Immunohistochemistry (IHC) 25 Antibodies 15 Antibodies 14 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies 12 Antibodies
Immunofluorescence (IF) 10 Antibodies 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(137), (62), (60), (1), (1), (1)
Host Rabbit
(124), (13)
Clonality
Polyclonal
Conjugate This VAV1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(115), (56), (23), (12), (9), (7), (6), (3), (1), (1), (1)
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling Images
Specificity This antibody detects endogenous levels of VAV1 protein. (region surrounding Ala168)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins, deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. These results suggest that p95Vav may represent a new type of signal transduction molecule involved in the transduction of tyrosine phosphorylation signaling into transcriptional events.Synonyms: Proto-oncogene vav, VAV-1
Molecular Weight approx. 100 kDa
Gene ID 7409
NCBI Accession NP_005419
UniProt P15498
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling Images back to top
Application Notes ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling back to top
Supplier Images
 image for anti-VAV1 antibody (Vav 1 Oncogene) (ABIN271858) anti-Vav 1 Oncogene (VAV1) antibody
 image for anti-VAV1 antibody (Vav 1 Oncogene) (ABIN271858) anti-Vav 1 Oncogene (VAV1) antibody (Image 2)