anti-Mouse (Murine) VAV1 antibody for Western Blotting

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
  • vav 1 guanine nucleotide exchange factor
  • vav 1 oncogene
  • VAV1
  • Vav1
  • vav1
Epitope
Middle Region
37
25
23
21
15
10
9
8
6
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
184
75
72
3
3
2
2
1
1
Host
Rabbit
134
51
Clonality
Polyclonal
Conjugate
This VAV1 antibody is un-conjugated
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
157
71
26
23
14
14
11
6
3
1
1
1
1
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Catalog No. ABIN2792554
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2214506 ABIN1533035 ELISA WB Rabbit IgG AA 141-190 Log in to see Polyclonal
3.2214506 ABIN1531997 ELISA WB Rabbit IgG AA 141-190, pTyr174 Log in to see Polyclonal
3.2214506 ABIN3187609 ELISA WB Rabbit IgG Tyr292 Log in to see Polyclonal
3.2214506 ABIN2855640 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
3.2214506 ABIN498714 WB Rabbit pTyr174 Log in to see Polyclonal
3.2214506 ABIN441430 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal
3.2214506 ABIN3187457 ELISA WB Rabbit IgG Tyr292 Log in to see Polyclonal
3.2214506 ABIN1870697 WB Rabbit IgG pTyr174 Log in to see Polyclonal
3.2214506 ABIN498591 WB Rabbit Log in to see Polyclonal
3.2214506 ABIN1875311 IHC WB Rabbit IgG Log in to see Polyclonal
3.2214506 ABIN1845803 IHC WB Rabbit pTyr174 Log in to see Polyclonal
3.2214506 ABIN2424893 WB Rabbit IgG pTyr174 Log in to see Polyclonal
3.2214506 ABIN1845805 IHC WB Rabbit Log in to see Polyclonal
3.2214506 ABIN5545359 WB Rabbit IgG Log in to see Polyclonal
3.2214506 ABIN1847540 ELISA WB Rabbit Internal Region, pTyr174 Log in to see Polyclonal
3.2214506 ABIN1848166 ELISA WB Rabbit Internal Region, pTyr174 Log in to see Polyclonal
1 ABIN711866 IF (p) IHC (p) WB Rabbit IgG AA 150-165, pTyr160 Log in to see Polyclonal
1 ABIN271858 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN362132 WB Rabbit IgG pTyr174 Log in to see Polyclonal 1
1 ABIN711875 IHC (p) WB HRP Rabbit IgG AA 150-165, pTyr160 Log in to see Polyclonal

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Epitope Middle Region
(37), (25), (23), (21), (15), (10), (9), (8), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(184), (75), (72), (3), (3), (2), (2), (1), (1)
Host Rabbit
(134), (51)
Clonality
Polyclonal
Conjugate This VAV1 antibody is un-conjugated
(5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(157), (71), (26), (23), (14), (14), (11), (6), (3), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN2792554) Images
Sequence RDRSELSLKE GDIIKILNKK GQQGWWRGEI YGRVGWFPAN YVEEDYSEYC
Cross-Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Predicted Reactivity Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 90%, Rat: 92%
Characteristics This is a rabbit polyclonal antibody against VAV1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human VAV1

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling References for anti-VAV1 antibody (ABIN2792554) Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background This protein is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: VAV
Protein Interaction Partner: UBC, CD28, ERBB3, ERBB2, EGFR, PTPN22, SPI1, PLCG1, Mbp, CD5, PDGFRB, NOTCH1, FGFR1, DOK1, TUBB, SH3BP2, CBLB, CBL, FYN, SYK, LCP2, CD19, SOCS1, KHDRBS1, LMNA, TUBA1A, PHAX, ZAP70, ZNF655, DOCK2, XRCC5, PAG1, RACGAP1, MERTK, BLNK, NEK3, AOC3, ARHGDIB, DNM
Protein Size: 845
Molecular Weight 98 kDa
Gene ID 7409
NCBI Accession NM_005428, NP_005419
UniProt P15498
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling References for anti-VAV1 antibody (ABIN2792554) Images back to top
Application Notes WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 845 AA

Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details References for anti-VAV1 antibody (ABIN2792554) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-VAV1 antibody (ABIN2792554)

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling Images back to top
Background publications

Schneider, Rudd: "CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 616-21, 2008

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN2792554) back to top
Supplier Images
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (Middle Region) antibody (ABIN2792554) WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...