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Vav 1 Oncogene ELISA Kits (VAV1)
On are 5 Vav 1 Oncogene (VAV1) ELISA Kits from 3 different suppliers available. Additionally we are shipping VAV1 Antibodies (169) and VAV1 Proteins (7) and many more products for this protein. A total of 185 VAV1 products are currently listed.
Vav, vav-T
list all ELISA KIts Gene Name GeneID UniProt
VAV1 7409 P15498
VAV1 25156  
VAV1 22324 P27870

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Human Vav 1 Oncogene (VAV1) interaction partners

  1. Polymorphisms of VAV1 gene is associated with Rheumatoid arthritis.

  2. Vav1 expression is increased in esophageal squamous cell carcinoma, indicates poor prognosis, and can serve as a candidate molecular prognostic marker.

  3. TGFbeta (show TGFB1 ELISA Kits) induced the dissociation of DNMT1 (show DNMT1 ELISA Kits) from the VAV1 promoter, leading to demethylation and the subsequent ectopic expression of VAV1 in cancer cells via a SMAD4 (show SMAD4 ELISA Kits)-dependent mechanism

  4. Our results suggest the existence of a Vav1/PU.1/miR (show MLXIP ELISA Kits)-142-3p network that supports all-trans retinoic acid -induced differentiation in acute promyelocytic leukemia (show PML ELISA Kits) -derived cells

  5. revealed a new function for Vav1 in the negative feedback regulation of the phosphorylation of immunoreceptor tyrosine-based activation motifs within the zeta chains, CD3 delta (show CD3D ELISA Kits), epsilon, gamma chains, as well as activation sites on the critical T cell tyrosine kinases

  6. Data indicate that only a single mutation in the proto-oncogene (show RAB1A ELISA Kits) Vav1 enhances tumorigenicity.

  7. These findings establish VAV1 as a critical epigenetically regulated oncogene (show RAB1A ELISA Kits) with a key role in MBSHH maintenance, and highlight its potential as a validated therapeutic target and prognostic biomarker for the improved therapy of medulloblastoma.

  8. The present study implies that estrogen-estrogen receptor (show ESR1 ELISA Kits) modulates the transcription and expression of Vav1, which may contribute to the proliferation of cancerous cells.

  9. The role of Vav1 in T leukemia survival by selectively triggering Rac2 (show RAC2 ELISA Kits)-Akt (show AKT1 ELISA Kits) axis and elevating the expression of anti-apoptotic Bcl-2 (show BCL2 ELISA Kits).

  10. results presented herein suggest a potential cross-talk between cancer cells and the microenvironment controlled by CSF1 (show CSF1 ELISA Kits)/Vav1 signaling pathways.

Mouse (Murine) Vav 1 Oncogene (VAV1) interaction partners

  1. Vav1 adaptor has a role in the production of inflammatory cytokines by effector T cells and in the susceptibility to neuroinflammation

  2. provide evidence that CD28 (show CD28 ELISA Kits) and the TCR complex regulate NF-kappaB (show NFKB1 ELISA Kits) via different signaling modules of GRB-2 (show GRB2 ELISA Kits)/VAV1 and LAT (show LAT ELISA Kits)/ADAP (show APP ELISA Kits) pathways respectively.

  3. Platelet P-Rex and Vav family Rac (show AKT1 ELISA Kits)-GEFs play important proinflammatory roles in leukocyte recruitment.

  4. The data show that vav1 not only affects transcription of the MHCII locus but also is an important regulator of MHCII protein transport to the cell surface.

  5. analyses revealed a SHP2 (show PTPN11 ELISA Kits)- and Lyn (show LYN ELISA Kits)-dependent pathway leading to phosphorylation of Vav1, Rac (show AKT1 ELISA Kits) activation, and F-actin polymerization in SCF (show KITLG ELISA Kits)-treated BMMCs

  6. Data indicate that Vav1 was a key negative regulator of macrophage-derived IL-6 (show IL6 ELISA Kits) production.

  7. Bruton's Tyrosine Kinase (BTK (show BTK ELISA Kits)) and Vav1 contribute to Dectin1 (show CLEC7A ELISA Kits)-dependent phagocytosis of Candida albicans in macrophages.

  8. Suggest that Vav1 act as critical molecular link coupling hyperlipidemia with proatherogenic monocyte/macrophage responses.

  9. Loss of Vav1 activity does not favour development of colitis-associated colon cancer.

  10. SH2 and SH3(B) domains of Vav1 are critical for the phosphorylation of Vav1 and its signalling function in TCR-induced calcium flux.

VAV1 Antigen Profile

Antigen Summary

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with VAV1

  • vav 1 guanine nucleotide exchange factor (VAV1) Elisa Kit
  • vav 1 guanine nucleotide exchange factor (Vav1) Elisa Kit
  • vav 1 oncogene (Vav1) Elisa Kit
  • vav 1 oncogene (vav1) Elisa Kit
  • Vav Elisa Kit
  • vav-T Elisa Kit

Protein level used designations for Vav 1 Oncogene (VAV1) ELISA Kits

vav 1 oncogene , proto-oncogene vav , p95 , p95vav , vav oncogene

455647 Pan troglodytes
7409 Homo sapiens
25156 Rattus norvegicus
485016 Canis lupus familiaris
617345 Bos taurus
100519821 Sus scrofa
22324 Mus musculus
446826 Xenopus laevis
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