Browse our VAV3 Proteins (VAV3)

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Vav 3 Oncogene Proteins (VAV3)
On are 6 Vav 3 Oncogene (VAV3) Proteins from 4 different suppliers available. Additionally we are shipping VAV3 Antibodies (90) and VAV3 Kits (11) and many more products for this protein. A total of 110 VAV3 products are currently listed.
A530094I06Rik, AA986410, Idd18.1, RGD1565941
list all proteins Gene Name GeneID UniProt
VAV3 10451 Q9UKW4
Rat VAV3 VAV3 295378  
Mouse VAV3 VAV3 57257 Q9R0C8

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VAV3 Proteins (VAV3) by Origin

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More Proteins for VAV3 Interaction Partners

Human Vav 3 Oncogene (VAV3) interaction partners

  1. Vav3 is a novel TRAF6 (show TRAF6 Proteins) interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

  2. this study shows that the anti-tumor effects of astragaloside IV are mediated by the downregulation of Vav3-mediated Rac1/MAPK (show MAPK1 Proteins) activation

  3. Our results indicated that individuals carrying the VAV3 rs7528153 TT genotype were at a significantly increased risk of developing Paget's Disease of Bone

  4. Vav3 was accumulated in cell protrusions, contributed to the formation of membrane protrusions, and thereby increased the motility and invasiveness of pancreatic ductal adenocarcinoma cells

  5. Vav3 inhibition can suppress cell activity and promote apoptosis by regulating the apoptosis-related genes through the ERK (show EPHB2 Proteins) pathway

  6. Data show that microRNA miR (show MLXIP Proteins)-499-5p targeted 3' untranslated regions (3'-UTR) of vav 3 oncogene protein (VAV3).

  7. Results found that OSR2, VAV3, and PPFIA3 (show PPFIA3 Proteins) were significantly hypermethylated in gastric cancer (GC) patients offering a good alternative in a simple, promising, and noninvasive detection of GC.

  8. Data show although no any significant differences between patient groups and lean subjects of proteins SYT4 (show SYT4 Proteins), BAG3 (show BAG3 Proteins), APOA1 (show APOA1 Proteins), and VAV3, except for VGF (show VGF Proteins) protein, there was a trend between the expression of these four genes and their protein levels.

  9. VAV3 overexpression is a novel biomarker for poor prognosis and survival in ovarian carcinoma.

  10. VAV3 overexpression could be a useful marker for predicting the outcomes of CRC (show CALR Proteins) patients and that VAV3 targeting represents a potential modality for treating CRC (show CALR Proteins)

Mouse (Murine) Vav 3 Oncogene (VAV3) interaction partners

  1. Vav3 is a regulator of retinal progenitor cell differentiation, thus highlighting a novel role for guanine nucleotide exchange factors in retinogenesis.

  2. Platelet P-Rex and Vav (show VAV1 Proteins) family Rac (show AKT1 Proteins)-GEFs play important proinflammatory roles in leukocyte recruitment.

  3. chow diet-fed Vav3 knockout mice develop an incomplete postreceptor insulin (show INS Proteins) state characterized by typical liver and plasma metabolic syndrome-like pathophysiologies that is not associated to other defects such as white adipocyte hypertrophy and obesity

  4. Data demonstrate that the co-expression of the exchange factors Vav2 and Vav3 is critical for the development of this tumor type.

  5. Vav2 and Vav3 are required for normal peripheral nerve degeneration/regeneration, revascularization and functional recovery.

  6. Vav3 collaborates with p190 (show CNTNAP1 Proteins)-BCR-ABL (show ABL1 Proteins) in lymphoid progenitor leukemogenesis, proliferation, and survival.

  7. Dectin-1 (show CLEC7A Proteins) activates the integrin Mac-1 (show ITGAM Proteins) in neutrophils via Vav1 (show VAV1 Proteins) and Vav3 signaling to promote Candida albicans clearance.

  8. study discloses an essential and nonredundant role for this Vav (show VAV1 Proteins) family member in axon guidance events in brainstem neurons that control blood pressure and respiratory rates

  9. CD36 (show CD36 Proteins) contributes to activation of Vav-1 (show VAV1 Proteins), -2, and -3 in aortae from hyperlipidemic mice

  10. Vav3 is a bona fide Ahr (show AHR Proteins) target that is in charge of a limited subset of the developmental and physiological functions controlled by this transcriptional factor.

VAV3 Protein Profile

Protein Summary

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with VAV3

  • vav 3 guanine nucleotide exchange factor (VAV3)
  • vav 3 guanine nucleotide exchange factor (Vav3)
  • vav 3 oncogene (Vav3)
  • A530094I06Rik protein
  • AA986410 protein
  • Idd18.1 protein
  • RGD1565941 protein

Protein level used designations for Vav 3 Oncogene Proteins (VAV3)

vav 3 oncogene , guanine nucleotide exchange factor VAV3 , VAV-3 , vav 3 protein

100057737 Equus caballus
694685 Macaca mulatta
100220994 Taeniopygia guttata
373939 Gallus gallus
10451 Homo sapiens
479921 Canis lupus familiaris
295378 Rattus norvegicus
521961 Bos taurus
57257 Mus musculus
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