Browse our anti-FEN1 (FEN1) Antibodies

Full name:
anti-Flap Structure-Specific Endonuclease 1 Antibodies (FEN1)
On are 128 Flap Structure-Specific Endonuclease 1 (FEN1) Antibodies from 24 different suppliers available. Additionally we are shipping FEN1 Proteins (55) and FEN1 Kits (5) and many more products for this protein. A total of 198 FEN1 products are currently listed.
AW538437, cb879, fen-1, fen1, mf1, rad2, xFEN1a
list all antibodies Gene Name GeneID UniProt
FEN1 14156  
FEN1 2237 P39748
FEN1 84490 Q5XIP6

Show all species

Show all synonyms

Most Popular Reactivities for anti-FEN1 (FEN1) Antibodies

Select your species and application

anti-Mouse (Murine) FEN1 Antibodies:

anti-Human FEN1 Antibodies:

anti-Rat (Rattus) FEN1 Antibodies:

All available anti-FEN1 Antibodies

Go to our pre-filtered search.

Top referenced anti-FEN1 Antibodies

  1. Human Monoclonal FEN1 Primary Antibody for ICC, IF - ABIN151083 : Qiu, Li, Frank, Shen: Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair. in The Journal of biological chemistry 2001 (PubMed)
    Show all 17 references for 151083

  2. Human Polyclonal FEN1 Primary Antibody for IP, WB - ABIN151786 : Muftuoglu, Wong, Imam, Wilson, Bohr, Opresko: Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta. in Cancer research 2006 (PubMed)
    Show all 7 references for 151786

  3. Human Polyclonal FEN1 Primary Antibody for ICC, IF - ABIN151787 : Farina, Shin, Kim, Bermudez, Kelman, Seo, Hurwitz: Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1. in The Journal of biological chemistry 2008 (PubMed)
    Show all 6 references for 151787

  4. Dog (Canine) Monoclonal FEN1 Primary Antibody for BI, WB - ABIN968459 : Harrington, Lieber: The characterization of a mammalian DNA structure-specific endonuclease. in The EMBO journal 1994 (PubMed)
    Show all 5 references for 968459

  5. Human Polyclonal FEN1 Primary Antibody for IF, WB - ABIN389376 : Hiraoka, Harrington, Gerhard, Lieber, Hsieh: Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human. in Genomics 1995 (PubMed)
    Show all 3 references for 389376

  6. Human Polyclonal FEN1 Primary Antibody for IF, IHC - ABIN1533720 : Taylor, Noguchi, Totoki, Toyoda, Kuroki, Dewar, Lloyd, Itoh, Takeda, Kim, She, Barlow, Bloom, Bruford, Chang, Cuomo, Eichler, FitzGerald, Jaffe, LaButti, Nicol, Park, Seaman, Sougnez, Yang, Zimmer et al.: Human chromosome 11 DNA sequence and analysis including novel gene identification. ... in Nature 2006 (PubMed)
    Show all 2 references for 1533720

  7. Cow (Bovine) Polyclonal FEN1 Primary Antibody for WB - ABIN2782483 : Liu, Qiu, Finger, Zheng, Shen: The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations. in Nucleic acids research 2006 (PubMed)

More Antibodies against FEN1 Interaction Partners

Arabidopsis thaliana Flap Structure-Specific Endonuclease 1 (FEN1) interaction partners

  1. Data show that shade avoidance 6 (SAV6; At5g26680), encodes flap endonuclease-1 (FEN1), assures proper root development through maintenance of genome integrity.

Mouse (Murine) Flap Structure-Specific Endonuclease 1 (FEN1) interaction partners

  1. These results reveal an important role of FEN1 phosphorylation to counteract oxygen-induced stress in the heart during the fetal-to-neonatal transition.

  2. WDR4 (show WDR4 Antibodies) regulates FEN1's potential DNA cleavage threat near the site of replication.

  3. The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN (show GEN1 Antibodies) activity, causing aneuploidy-associated cancers.

  4. PARP1 (show PARP1 Antibodies) is required for FEN1 recruitment to DNA repair intermediates in base excision repair.

  5. FFAA Fen1 mutation causes defective Pcna (show PCNA Antibodies) -coordinated Okazaki fragment maturation.

  6. A point mutation in the base excision repair gene flap endonuclease 1 causes a functional deficiency in repairing base damage, such that individuals carrying the mutation or similar mutations are predisposed to chemical-induced cancer development.

  7. FEN1 localization within the mitochondrial compartment of mouse brain tissue

  8. Distinct roles for two Mg2 (show MCOLN1 Antibodies)+ binding sites in the regulation of FEN-1 nuclease (show DCLRE1C Antibodies) activities include enhancement of DNA substrate binding ability and modulation of conformational changes.

  9. FEN1 has roles in DNA repair, as well as in DNA replication

  10. Fen1 is induced independently in mouse embryonic fibroblasts by ultraviolet (UV-C)light

Human Flap Structure-Specific Endonuclease 1 (FEN1) interaction partners

  1. Data indicate that human cancer-associated genetic alterations in the FEN1 gene can contribute substantially to cancer development.

  2. WRN (show RECQL2 Antibodies) or the Bloom syndrome helicase (BLM) stimulates DNA polymerase delta (show POLD1 Antibodies) progression across telomeric G-rich repeats, only WRN (show RECQL2 Antibodies) promotes sequential strand displacement synthesis and FEN1 cleavage.

  3. The FEN1 rs174538 A allele is a protective biomarker for childhood ALL and this association is more significant in males and in patients at onset age of 3.5 years or older.

  4. Data indicate that Flap endonuclease 1 (FEN1) single nucleotide polymorphisms and haplotypes are associated with gallbladder cancer risk.

  5. the aim of the present study was to determine the role of FEN1 in the chemosensitivity of SGC7901 cells.

  6. Binding of DNA to human FEN1 in a bent conformation occurred independently of 5'-flap (show ALOX5AP Antibodies) accommodation and did not require active site metal ions or the presence of conserved active site residues.

  7. In this study, we found that cohesion establishment factors, like CHlR1 (show DDX11 Antibodies), cooperatively stimulate endonuclease activity of hFen1 in in vivo mimic condition, including replication protein-A (show GPR153 Antibodies)-coated DNA and high salt.

  8. Under DNA repair conditions, FEN1 efficiently repaired the 5'-phoshotyrosyl bond-containing SSB substrates in the presence of DNA ligase and DNA polymerase (show POLB Antibodies).

  9. WDR4 (show WDR4 Antibodies) regulates FEN1's potential DNA cleavage threat near the site of replication.

  10. Patients with expression of both FEN1 and RAD54B (show RAD54B Antibodies) were prone to have advanced nodal involvement and significantly poor prognosis.

FEN1 Antigen Profile

Antigen Summary

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.

Alternative names and synonyms associated with FEN1

  • flap structure-specific endonuclease 1 (FEN1) antibody
  • flap endonuclease 1-like (LOC100808044) antibody
  • Flap endonuclease-1 (Bm1_49605) antibody
  • flap endonuclease-1 (AT5G26680) antibody
  • flap structure specific endonuclease 1 (Fen1) antibody
  • flap structure-specific endonuclease 1 (fen1) antibody
  • flap structure-specific endonuclease 1 (fen1-a) antibody
  • flap structure-specific endonuclease 1 (Fen1) antibody
  • nuclease, Rad2 family (FEN1) antibody
  • AW538437 antibody
  • cb879 antibody
  • fen-1 antibody
  • fen1 antibody
  • mf1 antibody
  • rad2 antibody
  • xFEN1a antibody

Protein level used designations for FEN1

flap endonuclease 1 , Flap structure-specific endonuclease 1 , flap structure-specific endonuclease 1 , DNase IV , maturation factor 1 , maturation factor-1 , 5' nuclease xFEN1a , FEN-1-A , flap endonuclease 1-A , flap structure-specific endonuclease 1-A , xFEN-1a , FEN-1

100059838 Equus caballus
100808044 Glycine max
6104806 Brugia malayi
832721 Arabidopsis thaliana
14156 Mus musculus
2237 Homo sapiens
386707 Danio rerio
394303 Xenopus laevis
769677 Gallus gallus
476063 Canis lupus familiaris
616242 Bos taurus
84490 Rattus norvegicus
100307042 Ovis aries
5721250 Chlamydomonas reinhardtii
Selected quality suppliers for anti-FEN1 (FEN1) Antibodies
Did you look for something else?