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Browse our H2A Histone Family, Member X (H2AFX) ELISA Kits

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H2A Histone Family, Member X ELISA Kits (H2AFX)
On www.antibodies-online.com are 13 H2A Histone Family, Member X (H2AFX) ELISA Kits from 7 different suppliers available. Additionally we are shipping H2A Histone Family, Member X Antibodies (312) and H2A Histone Family, Member X Proteins (9) and many more products for this protein. A total of 347 H2A Histone Family, Member X products are currently listed.
Synonyms:
AW228881, gammaH2ax, h2a, h2a.x, h2a/x, h2afx, h2ax, Hist5-2ax, RGD1566119, zgc:56329
list all ELISA KIts Gene Name GeneID UniProt
H2AFX 3014 P16104
H2AFX 15270 P27661
H2AFX 500987  

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Human H2A Histone Family, Member X (H2AFX) interaction partners

  1. dyserythropoiesis was increased in MDS patients with the deletion of chromosome 11q23, where H2AX is located. (show PAFAH1B1 ELISA Kits) Although loss of H2AX did not affect the early stage of terminal erythropoiesis, enucleation was decreased.

  2. the formation of 53BP1 (show TP53BP1 ELISA Kits), gammaH2AX foci and their co-localization induced by gamma-rays (2, 5, 10, 50, 200 cGy) in human lymphocytes, was analyzed.

  3. 5-Hydroxymethylcytosine (5hmC) accumulates at DNA damage foci and colocalizes with major DNA damage response proteins 53BP1 (show TP53BP1 ELISA Kits) and gH2AX, revealing 5hmC as an epigenetic marker of DNA damage.

  4. Anacardic acid sensitizes prostate cancer cells to radiation therapy by repressing H2AX expression.

  5. Results reveal a pathway controlled by ATM, SIRT6, and SNF2H to block HUWE1, which stabilizes H2AX and induces its incorporation into chromatin only when cells are damaged.

  6. Gene expression analysis identified deregulation of histone H2A and H2B genes in all four cell lines ;histone pathways are associated with epirubicin resistance

  7. kinetics of the accumulation of selected DNA repair-related proteins is protein specific at locally induced DNA lesions, and that the formation of gH2AX- and NBS1 (show NBN ELISA Kits)-positive foci, but not 53BP1 (show TP53BP1 ELISA Kits)-positive NBs (show NBN ELISA Kits), is cell cycle dependent in HeLa cells

  8. The interaction of MDC1 (show MDC1 ELISA Kits) with RNF8 (show RNF8 ELISA Kits), but not with ATM (show ATM ELISA Kits) requires WRAP53beta, suggesting that WRAP53beta facilitates the former interaction without altering phosphorylation of MDC1 (show MDC1 ELISA Kits) by ATM (show ATM ELISA Kits).

  9. the interaction of 53BP1 (show TP53BP1 ELISA Kits) with gammaH2AX is required for sustaining the 53BP1 (show TP53BP1 ELISA Kits)-dependent focal concentration of activated ATM (show ATM ELISA Kits) that facilitates repair of DNA double-strand breaks in heterochromatin in G1.

  10. X-rays induce prolonged and ATM (show ATM ELISA Kits)-independent persistence of gammaH2AX foci in human gingival mesenchymal stem cells

Mouse (Murine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. The role of H2AX phosphorylation and H3K56 acetylation on normal stem cell response to radiation

  2. H2AX knockout mice showed cell-autonomous anaemia and erythroid dysplasia, mimicking dyserythropoiesis in MDS (show MECOM ELISA Kits).

  3. These data suggest a role for FoxO3a in the maintenance of genome integrity in response to DNA damage that is mediated by H2AX via yet unknown mechanisms.

  4. overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation

  5. link gamma-H2AX to transcription, assigning a new function for this DNA damage marker

  6. DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination.

  7. Exposure to Cr(VI) induced villus blunting and crypt hyperplasia in the duodenum. gamma-H2AX immunostaining was elevated in villi, but not in the crypt compartment.

  8. Data indicate that crypts exposed to 180 ppm hexavalent chromium Cr(VI) appeared healthy and exhibited no difference in gammaH2ax (gamma-H2AX) staining relative to those of control.

  9. the gamma-H2AX biomarker showed higher sensitivity to measure dose-rate effects after low-dose LDR X rays compared to MNi formation.

  10. H2A.X is specifically targeted to and negatively regulates extraembryonic lineage gene expression in embryonic stem cells (ESCs (show NR2E3 ELISA Kits)) and prevents trophectoderm lineage differentiation.

Xenopus laevis H2A Histone Family, Member X (H2AFX) interaction partners

  1. These findings suggest a dimerize-then-rearrange model for H2A-H2B dimers.

  2. Findings reveal that XH2AX has a specific role in anterior neural formation of Xenopus, which is mediated through phosphorylation of XH2AX at Thr (show TRH ELISA Kits)(16) by Chk1 (show CHEK1 ELISA Kits).

Cow (Bovine) H2A Histone Family, Member X (H2AFX) interaction partners

  1. H2Ax phosphorylated protein was detected in in parthenogenetically activated, in vitro fertilized and cloned bovine embryos.

H2A Histone Family, Member X (H2AFX) Antigen Profile

Antigen Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Alternative names and synonyms associated with H2A Histone Family, Member X (H2AFX)

  • H2A histone family, member X (H2AFX) Elisa Kit
  • H2A histone family, member X (H2afx) Elisa Kit
  • H2A histone family, member X (h2afx) Elisa Kit
  • histone cluster 1, H2ah (HIST1H2AH) Elisa Kit
  • histone cluster 2, H2ab (hist2h2ab) Elisa Kit
  • histone H2A.x-like (LOC100522201) Elisa Kit
  • histone H2A.x-like (LOC100720536) Elisa Kit
  • AW228881 Elisa Kit
  • gammaH2ax Elisa Kit
  • h2a Elisa Kit
  • h2a.x Elisa Kit
  • h2a/x Elisa Kit
  • h2afx Elisa Kit
  • h2ax Elisa Kit
  • Hist5-2ax Elisa Kit
  • RGD1566119 Elisa Kit
  • zgc:56329 Elisa Kit

Protein level used designations for H2AFX

H2AX histone , histone H2A.x , H2a/x , histone 5 protein 2ax , H2A.X , histone H2A type 1

GENE ID SPECIES
3014 Homo sapiens
15270 Mus musculus
394048 Danio rerio
734746 Xenopus laevis
531733 Bos taurus
500987 Rattus norvegicus
418708 Gallus gallus
444528 Xenopus laevis
100522201 Sus scrofa
100720536 Cavia porcellus
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