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Browse our anti-DUOX2 (DUOX2) Antibodies

Full name:
anti-Dual Oxidase 2 Antibodies (DUOX2)
On www.antibodies-online.com are 37 Dual Oxidase 2 (DUOX2) Antibodies from 10 different suppliers available. Additionally we are shipping DUOX2 Kits (16) and DUOX2 Proteins (5) and many more products for this protein. A total of 59 DUOX2 products are currently listed.
Synonyms:
A430065P05Rik, LNOX2, NOXEF2, P138-TOX, TDH6, Thox2
list all antibodies Gene Name GeneID UniProt
DUOX2 50506 Q9NRD8
DUOX2 214593  
DUOX2 79107 Q9ES45

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Most Popular Reactivities for anti-DUOX2 (DUOX2) Antibodies

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anti-Human DUOX2 Antibodies:

anti-Mouse (Murine) DUOX2 Antibodies:

anti-Rat (Rattus) DUOX2 Antibodies:

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Top referenced anti-DUOX2 Antibodies

  1. Dog (Canine) Polyclonal DUOX2 Primary Antibody for ICC, IF - ABIN258884 : Morand, Chaaraoui, Kaniewski, Dème, Ohayon, Noel-Hudson, Virion, Dupuy: Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles. in Endocrinology 2003 (PubMed)
    Show all 5 references for ABIN258884

  2. Human Polyclonal DUOX2 Primary Antibody for EIA, FACS - ABIN951993 : Salmeen, Park, Meyer: The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway. in Oncogene 2010 (PubMed)
    Show all 2 references for ABIN951993

More Antibodies against DUOX2 Interaction Partners

Human Dual Oxidase 2 (DUOX2) interaction partners

  1. xome sequencing identified candidate variants, including a missense mutation in DUOX2 that impaired its function and a frameshift mutation in CSF2RB (show CSF2RB Antibodies) that was associated with Crohn's Disease in an independent cohort of Ashkenazi Jewish individuals.

  2. Data suggest that mutations in DUOX2 may be the most common cause of both permanent congenital hypothyroidism and transient hypothyroidism; severity of disease due to DUOX2 mutations may be milder than that due to other causes. This study involved neonatal screening of 48 Japanese boys and girls.

  3. DUOX2 Mutation is associated with Congenital Hypothyroidism.

  4. Nox4 (show NOX4 Antibodies) and Duox1/Duox2 (show DUOX1 Antibodies) mediate redox activation of mesenchymal cell migration by PDGF (show PDGFA Antibodies).

  5. The high prevalence of DUOX2 mutations in this cohort of children with Congenial hypothyroidism appears striking and surprising. The clinical implications were discussed.

  6. study expanded the mutational spectrum of the DUOX2 and thyroglobulin (show TG Antibodies) genes and provided the best estimation of the DUOX2 mutation rate (29%) for congenital hypothyroidism/subclinical congenital hypothyroidism patients in Guangxi Zhuang Autonomous Region of China

  7. Seven different recurrent mutations [p.G488R (n=13), p.A649E (n=3), p.R885Q (n=3), p.I1080T (n=2), and p.A1206T (n=2) in DUOX2; p.Y138X (n=9) in DUOXA2 (show DUOXA2 Antibodies)) were identified as the mutations underlying congenital hypothyroidism.

  8. Transient congenital hypothyroidism is caused by compound heterozygous mutations affecting the NADPH-oxidase (show NOX1 Antibodies) domain of DUOX2.

  9. the house dust mite-dependent TLR2 (show TLR2 Antibodies)-Duox2 signalling axis promotes NF-kappaB (show NFKB1 Antibodies) activation, which induces IL-8 (show IL8 Antibodies) and CCL20 (show CCL20 Antibodies) production and mediates epidermal keratinocyte inflammation

  10. Results identified 2 mutations in DUOX2 gene from patient with congenital hypothyroidism and report new cryptic splicing sites in the intron 17 and exon 18.

Pig (Porcine) Dual Oxidase 2 (DUOX2) interaction partners

  1. the dual oxidase 2 N-terminal region is targeted to the plasma membrane

Mouse (Murine) Dual Oxidase 2 (DUOX2) interaction partners

  1. DUOX2 (show DUOX1 Antibodies) regulates interactions between the intestinal microbiota and the mucosa to maintain immune homeostasis in mice.

  2. these data indicate that the gut (show GUSB Antibodies) microbiota uses two distinct signaling pathways to induce Duox2 (show DUOX1 Antibodies) expression in the ileum and colon epithelium.

  3. Data suggest that proteinase-activated receptor 2 (show F2RL1 Antibodies) activation leads to up-regulation of the dual oxidase-2 (show DUOX1 Antibodies)/reactive oxygen species pathway in airway epithelial cells (AECs).

  4. DUOX2 (show DUOX1 Antibodies)-generated ROS (show ROS1 Antibodies) induce AEC death.

  5. a spontaneously generated valine 674-to-glycine mutation of murine Duox2 (show DUOX1 Antibodies) results in a translocation defect and complete loss of function that explains the severe congenital hypothyroid phenotype of the thyd/thyd mouse strain

  6. DUOX2 (show DUOX1 Antibodies) plays pivotal roles in TLR5 (show TLR5 Antibodies)-dependent inflammatory response of nasal airway epithelium.

  7. DUOX2 (show DUOX1 Antibodies) and NOD2 (show NOD2 Antibodies) cooperatively facilitate antibacterial action.

DUOX2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Alternative names and synonyms associated with DUOX2

  • dual oxidase 2 (DUOX2) antibody
  • dual oxidase 2 (Duox2) antibody
  • A430065P05Rik antibody
  • LNOX2 antibody
  • NOXEF2 antibody
  • P138-TOX antibody
  • TDH6 antibody
  • Thox2 antibody

Protein level used designations for anti-Dual Oxidase 2 (DUOX2) Antibodies

dual oxidase 2 , dual oxidase 2-like , NADH/NADPH thyroid oxidase p138-tox , NADPH oxidase/peroxidase DUOX2 , NADPH thyroid oxidase 2 , dual oxidase-like domains 2 , flavoprotein NADPH oxidase , large NOX 2 , long NOX 2 , nicotinamide adenine dinucleotide phosphate oxidase , p138 thyroid oxidase , thyroid oxidase 2 , NADH/NADPH thyroid oxidase THOX2

GENE ID SPECIES
100070566 Equus caballus
427482 Gallus gallus
453395 Pan troglodytes
785698 Bos taurus
100445893 Pongo abelii
100462743 Ovis aries
50506 Homo sapiens
403719 Canis lupus familiaris
397060 Sus scrofa
214593 Mus musculus
79107 Rattus norvegicus
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