Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human DUOX2 Antibodies:
anti-Mouse (Murine) DUOX2 Antibodies:
anti-Rat (Rattus) DUOX2 Antibodies:
Go to our pre-filtered search.
Dog (Canine) Polyclonal DUOX2 Primary Antibody for ICC, IF - ABIN258884
Morand, Chaaraoui, Kaniewski, Dème, Ohayon, Noel-Hudson, Virion, Dupuy: Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles. in Endocrinology 2003
Show all 5 Pubmed References
Human neutrophil elastase (show ELANE Antibodies) is involved in transactivation of TLR4 (show TLR4 Antibodies) through activation of DUOX-2/EGFR (show EGFR Antibodies) and synergistically enhances IL-12p40 production by macrophages stimulated with LPS (show IRF6 Antibodies).
Monoallelic TSHR (show TSHR Antibodies) mutations are significantly associated with positive newborn screen for congenital hypothyroidism, and the association is further strengthened by the coexistence of monoallelic DUOX2 mutations.
In addition to thyroid hormonogenesis, the DUOX2 N-terminal domain may play a role in thyroid development.
This study reports the pedigree with goitrous congenital hypothyroidism (GCH (show GCH1 Antibodies)) due to the coexistence of heterozygous mutations in the DUOX2 and DUOXA2 (show DUOXA2 Antibodies) genes.
DUOX2 nonsense mutation plays a role in the pathogenesis of congenital hypothyroidism.
Expression of DUOX2 mRNA and protein was lower in gastric mucosa of patients with H. pylori infection compared to the uninfected. Among the H. pylori-infected patients, those having CagA (show S100A8 Antibodies) IgG or VacA in the serum had lower DUOX2 expression levels than those infected with H. pylori without either virulence factor.
xome sequencing identified candidate variants, including a missense mutation in DUOX2 that impaired its function and a frameshift mutation in CSF2RB (show CSF2RB Antibodies) that was associated with Crohn's Disease in an independent cohort of Ashkenazi Jewish individuals.
Data suggest that mutations in DUOX2 may be the most common cause of both permanent congenital hypothyroidism and transient hypothyroidism; severity of disease due to DUOX2 mutations may be milder than that due to other causes. This study involved neonatal screening of 48 Japanese boys and girls.
DUOX2 Mutation is associated with Congenital Hypothyroidism.
Nox4 (show NOX4 Antibodies) and Duox1/Duox2 (show DUOX1 Antibodies) mediate redox activation of mesenchymal cell migration by PDGF (show PDGFA Antibodies).
A novel recessive c.1226A>G transition of the dual oxidase 2 gene was identified as the causative mutation for a severe congenital hypothyroidism model together with anemia and T lymphopenia which mimics the clinical features of hypothyroid patients
the dual oxidase 2 N-terminal region is targeted to the plasma membrane
Both Nox1 (show NOX1 Antibodies) and Duox2 (show DUOX1 Antibodies) induce exfoliation of crypt epithelium, but only Nox1 (show NOX1 Antibodies) induces apoptosis. NOX1 (show NOX1 Antibodies) and DUOX2 (show DUOX1 Antibodies) may be potential therapeutic targets for treating ileocolitis in human patients suffering inflammatory bowel disease (IBD).
dual oxidase-2 (show DUOX1 Antibodies) and IL-6 (show IL6 Antibodies) play important roles in GPR43 (show FFAR2 Antibodies)-mediated skin inflammation.
We propose that Duox2 (show DUOX1 Antibodies) is responsible for IFN-independent signaling for induction of pattern recognition receptors transcription and can control acute Influenza virus A infection at the beginning of infection.
DUOX2 (show DUOX1 Antibodies) regulates interactions between the intestinal microbiota and the mucosa to maintain immune homeostasis in mice.
these data indicate that the gut (show GUSB Antibodies) microbiota uses two distinct signaling pathways to induce Duox2 (show DUOX1 Antibodies) expression in the ileum and colon epithelium.
Data suggest that proteinase-activated receptor 2 (show F2RL1 Antibodies) activation leads to up-regulation of the dual oxidase-2 (show DUOX1 Antibodies)/reactive oxygen species pathway in airway epithelial cells (AECs).
DUOX2 (show DUOX1 Antibodies)-generated ROS (show ROS1 Antibodies) induce AEC death.
a spontaneously generated valine 674-to-glycine mutation of murine Duox2 (show DUOX1 Antibodies) results in a translocation defect and complete loss of function that explains the severe congenital hypothyroid phenotype of the thyd/thyd mouse strain
DUOX2 (show DUOX1 Antibodies) plays pivotal roles in TLR5 (show TLR5 Antibodies)-dependent inflammatory response of nasal airway epithelium.
DUOX2 (show DUOX1 Antibodies) and NOD2 (show NOD2 Antibodies) cooperatively facilitate antibacterial action.
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
dual oxidase 2
, dual oxidase 2-like
, NADH/NADPH thyroid oxidase p138-tox
, NADPH oxidase/peroxidase DUOX2
, NADPH thyroid oxidase 2
, dual oxidase-like domains 2
, flavoprotein NADPH oxidase
, large NOX 2
, long NOX 2
, nicotinamide adenine dinucleotide phosphate oxidase
, p138 thyroid oxidase
, thyroid oxidase 2
, NADH/NADPH thyroid oxidase THOX2