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PRKX, WNT3 (show WNT3 Proteins) and WNT16 (show WNT16 Proteins) genes, belonging to the WNT (show WNT2 Proteins) signaling pathway, are involved in the tumorigenic process of nodular basal cell carcinoma
The characteristics and developmental functions of PRKX. [review]
findings reveals a major role of PRKX, TTBK2 (show TTBK2 Proteins) and RSK4 (show RPS6KA6 Proteins) in triggering Sunitinib resistance formation; data suggest transcriptional regulation of these kinases together with other proteins might play an important role in formation of Sunitinib resistance by affecting transcription factors
MBD 4 (show MBD4 Proteins)--a potential substrate for protein kinase X
The interaction of PRKX with Pin-1 (show PIN1 Proteins), Magi-1 (show MAGI1 Proteins) and Bag-3 (show BAG3 Proteins) could contribute to the stimulating role of PRKX in angiogenesis.
PRKX kinase may regulate epithelial morphogenesis during mammalian kidney development.
PRKX can restore normal function to PKD1 (show PKD1 Proteins)-deficient kidneys and have implications for the development of preventative therapy for autosomal dominant polycystic kidney disease
The interaction of PRKX with Pin-1 (show PIN1 Proteins), Magi-1 (show CNKSR3 Proteins) and Bag-3 (show BAG3 Proteins) could contribute to the stimulating role of PRKX in angiogenesis.
This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.
protein kinase, X-linked
, protein kinase, X-linked-like
, cAMP-dependent protein kinase catalytic subunit PRKX
, protein kinase PKX1
, protein kinase X
, protein kinase X-linked
, serine/threonine-protein kinase PRKX
, PKA-related protein kinase
, putative serine/threonine kinase