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Browse our anti-Interferon Regulatory Factor 3 (IRF3) Antibodies

Full name:
anti-Interferon Regulatory Factor 3 Antibodies (IRF3)
On www.antibodies-online.com are 270 Interferon Regulatory Factor 3 (IRF3) Antibodies from 32 different suppliers available. Additionally we are shipping Interferon Regulatory Factor 3 Kits (31) and Interferon Regulatory Factor 3 Proteins (22) and many more products for this protein. A total of 340 Interferon Regulatory Factor 3 products are currently listed.
Synonyms:
C920001K05Rik, IRF-3, IRF3
list all antibodies Gene Name GeneID UniProt
IRF3 3661 Q14653
IRF3 54131 P70671
IRF3 292892  

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Most Popular Reactivities for anti-Interferon Regulatory Factor 3 (IRF3) Antibodies

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Top referenced anti-Interferon Regulatory Factor 3 Antibodies

  1. Human Monoclonal IRF3 Primary Antibody for Inhibition, IF - ABIN967285 : Au, Moore, Lowther, Juang, Pitha: Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 8 references for ABIN967285

  2. Mouse (Murine) Polyclonal IRF3 Primary Antibody for WB - ABIN1881465 : Marichal, Bedoret, Mesnil, Pichavant, Goriely, Trottein, Cataldo, Goldman, Lekeux, Bureau, Desmet: Interferon response factor 3 is essential for house dust mite-induced airway allergy. in The Journal of allergy and clinical immunology 2010 (PubMed)
    Show all 5 references for ABIN1881465

  3. Human Polyclonal IRF3 Primary Antibody for IF (cc), IF (p) - ABIN742688 : Menasria, Boivin, Lebel, Piret, Gosselin, Boivin: Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection. in Journal of virology 2013 (PubMed)
    Show all 2 references for ABIN742688

  4. Human Monoclonal IRF3 Primary Antibody for EIA, WB - ABIN317099 : DeFilippis, Robinson, Keck, Hansen, Nelson, Früh: Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection. in Journal of virology 2005 (PubMed)
    Show all 2 references for ABIN317099

  5. Mouse (Murine) Polyclonal IRF3 Primary Antibody for IHC, WB - ABIN3023115 : Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. in PLoS ONE 2013 (PubMed)

  6. Human Polyclonal IRF3 Primary Antibody for IF, IHC - ABIN2490915 : Dong, Liu, Zhao, Wang, Pei, Luo, Ju, Chen et al.: Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar ... in Virology journal 2013 (PubMed)

  7. Human Polyclonal IRF3 Primary Antibody for EIA, IF - ABIN500056 : Malmgaard: Induction and regulation of IFNs during viral infections. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 (PubMed)

  8. Cow (Bovine) Polyclonal IRF3 Primary Antibody for WB - ABIN2779404 : Korherr, Gille, Schäfer, Koenig-Hoffmann, Dixelius, Egland, Pastan, Brinkmann: Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

More Antibodies against Interferon Regulatory Factor 3 Interaction Partners

Zebrafish Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Interferon (show IFNA Antibodies) regulatory factor (IRF (show TRIM63 Antibodies))10 inhibits the expression of IFN1 and IFN3 to avoid an excessive immune response, a unique regulation mechanism of the IFN responses in lower vertebrates.

Rhesus Monkey Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Hepatitis A virus protein 2B suppresses beta interferon (show IFNA Antibodies) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Atlantic Salmon (Salmo salar) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. MyD88 (show MYD88 Antibodies) interacts with interferon (show IFNA Antibodies) regulatory factor (IRF) 3 and IRF7 (show IRF7 Antibodies) in Atlantic salmon (Salmo salar)

Human Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. FAF1 (show FAF1 Antibodies) plays a novel role in negatively regulating virus-induced IFN-beta (show IFNB1 Antibodies) production and the antiviral response by inhibiting the translocation of active, phosphorylated IRF3 from the cytosol to the nucleus

  2. the LxxLL motifs of IRF3 binds within the hydrophobic pocket of E6, precluding Ser (show SIGLEC1 Antibodies)-patch phosphorylation, necessary for IRF3 activation and interferon (show IFNA Antibodies) induction.

  3. the suppression of type I IFN production by HTLV-1 Tax (show CNTN2 Antibodies) through interaction with and inhibition of TBK1 (show TBK1 Antibodies) kinase that phosphorylates IRF3

  4. The authors found that Ca(2 (show CA2 Antibodies)+) signaling associated with membrane perturbation and recognition of incoming viral genomes by cytosolic nucleic acid receptors are required to activate IRF3 in response to Sendai virus and human cytomegalovirus.

  5. Study identifies crosstalk between PTEN (show PTEN Antibodies) and IRF3 in tumor suppression and innate immunity.

  6. Viral infection induced DAPK1 (show DAPK1 Antibodies)-IRF7 (show IRF7 Antibodies) and DAPK1 (show DAPK1 Antibodies)-IRF3 interactions and overexpression of DAPK1 (show DAPK1 Antibodies) enhanced virus-induced activation of the interferon (show IFNA Antibodies)-stimulated response element (ISRE) and IFN-beta (show IFNB1 Antibodies) promoters and the expression of the IFNB1 (show IFNB1 Antibodies) gene.

  7. TEL (show ETV6 Antibodies)-AML1 (show RUNX1 Antibodies) fusion protein blocks B-cell differentiation and downregulates the IRF3-IFNalpha/beta pathway by modulating expression and phosphorylation of IRF3 in human primary hematopoietic precursor cells.

  8. The expression levels of IRF3 were not different between CHB patients and healthy controls.

  9. results revealed a new paradigm in which the antiviral host factor, IRF3, plays a cell-intrinsic pro-parasitic role.

  10. The results of this study suggested that IRF3 is likely a risk gene for schizophrenia, at least in Caucasians.

Pig (Porcine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 and subsequent degradation of IRF-3, leading to downregulation of IFN-alpha (show IFNA Antibodies)/beta production.

  2. The obtained results showed that PRRSV nsp1 could inhibit Poly(I:C)-induced IFN-beta (show IFNB1 Antibodies) promoter activity in MARC (show CCL7 Antibodies)-145 cells by down-regulating the protein level of IRF-3 and inhibiting the phosphorylation of IRF-3.

  3. proteasomal degradation of IRF3 is induced by a direct or indirect interaction with N(pro).

Mouse (Murine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 Antibodies))-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 Antibodies)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3).

  2. characterizes SREBP cleavage-activating protein as an essential adaptor in the STING signaling pathway

  3. Study identifies crosstalk between PTEN (show PTEN Antibodies) and IRF3 in tumor suppression and innate immunity.

  4. results revealed a new paradigm in which the antiviral host factor, IRF3, plays a cell-intrinsic pro-parasitic role.

  5. Irf3/IFN activation in hematopoietic stem and progenitor cells expands multipotent progenitors fractions but inhibits HSC (show FUT1 Antibodies) mobilization

  6. find that IRF3 versus ISGF3 (show IRF9 Antibodies) specificity may be critical to limiting IFN-beta (show IFNB1 Antibodies) production and ISGF3 (show IRF9 Antibodies) activation, temporally and spatially, but that partial overlap in their specificity is tolerable and may enhance the effectiveness of the innate-immune response

  7. Bipartite nuclear localization signal controls nuclear import and DNA-binding activity of IRF3.

  8. Our findings delineate a novel mechanism for the termination of IRF3 activation in nucleus through TRIM26 (show TRIM26 Antibodies)-mediated IRF3 ubiquitination and degradation.

  9. PP1 (show PPP1CC Antibodies) directly interacts with IRF3 and dephosphorylates IRF3 at Ser385 and Ser396, resulting in the suppression of TLR- and RLR (show DHX58 Antibodies)-triggered IFN-beta (show IFNB1 Antibodies) production.

  10. our results identify CK2 (show CSNK2A1 Antibodies) as a novel regulator of TBK1 (show TBK1 Antibodies) and IRF3 and suggest that targeting CK2 (show CSNK2A1 Antibodies) by small molecular inhibitor may be a viable approach to prevent and treat viral infections.

Cow (Bovine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta (show IFNB1 Antibodies) promoter activity and induces IRF3 degradation.

  2. cpBVDV infection causes a marked loss of interferon regulatory factor 3 (IRF-3), a cellular transcription factor that controls interferon (show IFNA Antibodies) synthesis.

Interferon Regulatory Factor 3 (IRF3) Antigen Profile

Antigen Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Interferon Regulatory Factor 3 (IRF3)

  • interferon regulatory factor 3 (irf3) antibody
  • interferon regulatory factor 3 (IRF3) antibody
  • interferon regulatory factor 3 (irf-3) antibody
  • interferon regulatory factor 3 (Irf3) antibody
  • interferon regulatory factor 7 (IRF7) antibody
  • C920001K05Rik antibody
  • IRF-3 antibody
  • IRF3 antibody

Protein level used designations for IRF3

interferon regulatory factor 3 , interferon regulatory factor 3-like , IRF-3

GENE ID SPECIES
564854 Danio rerio
718970 Macaca mulatta
747565 Pan troglodytes
780485 Ovis aries
100337625 Salmo salar
100414132 Callithrix jacchus
100441280 Pongo abelii
100471184 Ailuropoda melanoleuca
3661 Homo sapiens
396656 Sus scrofa
54131 Mus musculus
292892 Rattus norvegicus
476412 Canis lupus familiaris
516979 Bos taurus
396330 Gallus gallus
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