Browse our anti-Interferon Regulatory Factor 3 (IRF3) Antibodies

On www.antibodies-online.com are 307 Interferon Regulatory Factor 3 (IRF3) Antibodies from 33 different suppliers available. Additionally we are shipping Interferon Regulatory Factor 3 Kits (33) and Interferon Regulatory Factor 3 Proteins (20) and many more products for this protein. A total of 377 Interferon Regulatory Factor 3 products are currently listed.
Synonyms:
C920001K05Rik, IRF-3, IRF3
list all antibodies Gene Name GeneID UniProt
IRF3 3661 Q14653
IRF3 54131 P70671
IRF3 292892  

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More Antibodies against Interferon Regulatory Factor 3 Interaction Partners

Zebrafish Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Following spring viremia of carp (show ANKRD1 Antibodies) virus infection, DrIFNPhi1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues, which correlates with the replication of spring viremia of carp (show ANKRD1 Antibodies) virus. data provide evidence that fish and mammals have evolved a similar IRF (show TRIM63 Antibodies)-dependent regulatory mechanism fine-tuning IFN gene activation.

  2. Interferon (show IFNA Antibodies) regulatory factor (IRF (show TRIM63 Antibodies))10 inhibits the expression of IFN1 and IFN3 to avoid an excessive immune response, a unique regulation mechanism of the IFN responses in lower vertebrates.

Rhesus Monkey Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Hepatitis A virus protein 2B suppresses beta interferon (show IFNA Antibodies) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Atlantic Salmon (Salmo salar) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. MyD88 (show MYD88 Antibodies) interacts with interferon (show IFNA Antibodies) regulatory factor (IRF) 3 and IRF7 (show IRF7 Antibodies) in Atlantic salmon (Salmo salar)

Human Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. this study shows that IRF-3-mediated apoptosis of virus-infected cells could be an effective antiviral mechanism, without expression of the interferon (show IFNA Antibodies)-stimulated genes

  2. Data in this study show that cFLIPL inhibits IFN regulatory factor 3 (IRF3), a transcription factor central for IFN-beta (show IFNB1 Antibodies) and IFN-stimulated gene expression.

  3. 1,8-cineole potentiates the antiviral activity of IRF3 in addition to its inhibitory effect on proinflammatory NF-kappaB (show NFKB1 Antibodies) signaling in an ex vivo model of rhinosinusitis.

  4. TBK1 (show TBK1 Antibodies) complexes required for the phosphorylation of IRF3 and the production of interferon-beta (show IFNB1 Antibodies) have been identified.

  5. RIG-I (show DDX58 Antibodies)-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

  6. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 and subsequent type I interferon (show IFNA Antibodies) production. (Review)

  7. IRF3 overexpression in Acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)) promotes cell growth and survival, and miR (show MLXIP Antibodies)-155 is involved, indicating that IRF3 may be a potential new biomarker and therapeutic target for AML (show RUNX1 Antibodies).

  8. down-regulation of IRF3 inhibited the proliferation and extracellular matrix expression in keloid fibroblasts.

  9. rotavirus NSP1 (show SH2D3A Antibodies) (nonstructural protein 1) employs a pLxIS motif to target IRF-3 for degradation, but phosphorylation of NSP1 (show SH2D3A Antibodies) is not required for its activity. These results suggest a concerted mechanism for the recruitment and activation of IRF-3 that can be subverted by viral proteins to evade innate immune responses.

  10. Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta (show IFNB1 Antibodies) expression mainly through attenuating IRF-3 phosphorylation.

Pig (Porcine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. The authors used recombinant classical swine fever virus N(pro) and swine IRF3 proteins and show that N(pro) interacts with IRF3 directly without additional proteins and forms a soluble 1:1 complex.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 and subsequent degradation of IRF-3, leading to downregulation of IFN-alpha (show IFNA Antibodies)/beta production.

  3. The obtained results showed that PRRSV nsp1 could inhibit Poly(I:C)-induced IFN-beta (show IFNB1 Antibodies) promoter activity in MARC (show CCL7 Antibodies)-145 cells by down-regulating the protein level of IRF-3 and inhibiting the phosphorylation of IRF-3.

  4. proteasomal degradation of IRF3 is induced by a direct or indirect interaction with N(pro).

Mouse (Murine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. Findings indicate that STING-TBK1 (show TBK1 Antibodies)-IRF3 pathway mediates a crosstalk between ER stress and apoptosis during M. bovis infection, which can effectively control intracellular bacteria.

  2. GPR146 has an antiviral role in fighting against viral infection, although the GPR146-mediated protection is eliminated by IRF3/HES1-signalling.

  3. this study shows that IRF-3-mediated apoptosis of virus-infected cells could be an effective antiviral mechanism, without expression of the interferon (show IFNA Antibodies)-stimulated genes

  4. Results establish Irf3, known mostly for its role in antiviral responses, as a transcription factor involved in the induction of Th2 responses through the promotion of pro-Th2 costimulation in CD11b (show ITGAM Antibodies)(+) dendritic cells

  5. Rubicon (show KIAA0226 Antibodies) specifically interacts with the interferon (show IFNA Antibodies) regulatory factor (IRF (show TRIM63 Antibodies)) association domain (IAD) of IRF3, and this interaction leads to inhibition of the dimerization of IRF3, which negatively regulates interferon (show IFNA Antibodies)-mediated antiviral response.

  6. this study shows that IRF3 in antigen-presenting cells and T cells is required for optimal T-cell effector function and the ability of T cells to influence innate immune function of antigen-presenting cells

  7. The mitochondrial damage-cGAS-STING-IRF3 pathway is critically involved in metabolic stress-induced endothelial inflammation.

  8. TBK1 (show TBK1 Antibodies) complexes required for the phosphorylation of IRF3 and the production of interferon-beta (show IFNB1 Antibodies) have been identified.

  9. this study shows that lipopolysaccharide priming of dendritic cells stabilizes their tolerogenicity through reduction of NF-kappaB (show NFKB1 Antibodies) and IRF3 signaling

  10. this study shows that regulation of the IRF3 pathway can affect multiple cell types and contribute to ameliorate pathogenesis of infection-triggered exacerbation of chronic obstructive pulmonary disease

Cow (Bovine) Interferon Regulatory Factor 3 (IRF3) interaction partners

  1. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta (show IFNB1 Antibodies) promoter activity and induces IRF3 degradation.

  2. cpBVDV infection causes a marked loss of interferon regulatory factor 3 (IRF-3), a cellular transcription factor that controls interferon (show IFNA Antibodies) synthesis.

Interferon Regulatory Factor 3 (IRF3) Antigen Profile

Antigen Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Interferon Regulatory Factor 3 (IRF3)

  • interferon regulatory factor 3 (irf3) antibody
  • interferon regulatory factor 3 (IRF3) antibody
  • interferon regulatory factor 3 (irf-3) antibody
  • interferon regulatory factor 3 (Irf3) antibody
  • interferon regulatory factor 7 (IRF7) antibody
  • C920001K05Rik antibody
  • IRF-3 antibody
  • IRF3 antibody

Protein level used designations for IRF3

interferon regulatory factor 3 , interferon regulatory factor 3-like , IRF-3

GENE ID SPECIES
564854 Danio rerio
718970 Macaca mulatta
747565 Pan troglodytes
780485 Ovis aries
100337625 Salmo salar
100414132 Callithrix jacchus
100441280 Pongo abelii
100471184 Ailuropoda melanoleuca
3661 Homo sapiens
396656 Sus scrofa
54131 Mus musculus
292892 Rattus norvegicus
476412 Canis lupus familiaris
516979 Bos taurus
396330 Gallus gallus
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