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Browse our IRF7 Proteins (IRF7)

Full name:
Interferon Regulatory Factor 7 Proteins (IRF7)
On are 3 Interferon Regulatory Factor 7 (IRF7) Proteins from 2 different suppliers available. Additionally we are shipping IRF7 Antibodies (143) and IRF7 Kits (5) and many more products for this protein. A total of 157 IRF7 products are currently listed.
IRF-7H, irf7, IRF7A, IRF7B, IRF7C, IRF7H, wu:fl24c03, zgc:66043, zgc:77947
list all proteins Gene Name GeneID UniProt
IRF7 3665 Q92985
IRF7 54123 P70434
Rat IRF7 IRF7 293624  

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IRF7 Proteins (IRF7) by Origin

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More Proteins for IRF7 Interaction Partners

Zebrafish Interferon Regulatory Factor 7 (IRF7) interaction partners

  1. Functions of the two zebrafish MAVS (show MAVS Proteins) variants are opposite in the induction of IFN1 by targeting IRF7

  2. The miR (show MYLIP Proteins)-142a-3p regulates HSC (show FUT1 Proteins) formation and differentiation through the repression of interferon regulatory factor 7 (irf7)-mediated inflammation signaling.

Atlantic Salmon (Salmo salar) Interferon Regulatory Factor 7 (IRF7) interaction partners

  1. MyD88 (show MYD88 Proteins) interacts with interferon (show IFNA Proteins) regulatory factor (IRF) 3 (show IRF3 Proteins) and IRF7 in Atlantic salmon (Salmo salar)

  2. Differences in transcription kinetics between IRF-7 and STAT1 (show STAT1 Proteins) indicate that genes are regulated through different pathways. Infection of TO cells with ISAV induced early synthesis of STAT1 (show STAT1 Proteins) mRNA, whereas IRF-7 transcripts were upregulated later.

Human Interferon Regulatory Factor 7 (IRF7) interaction partners

  1. KSHV-encoded viral IRF4 (show IRF4 Proteins) interacts with the host IRF7 and inhibits interferon-alpha (show IFNA Proteins) production.

  2. The adaptor molecule RAIDD (show CRADD Proteins) coordinates IKKepsilon (show IKBKE Proteins) and IRF7 interaction to ensure efficient expression of type I interferon (show IFNA Proteins).

  3. Bcl6 (show BCL6 Proteins), by interacting with the co-factors NcoR2 and HDAC3 (show HDAC3 Proteins), plays a pivotal role in controlling IRF7 induction and antiviral signaling priming.

  4. Human IRF7 was shown to be essential for interferon (show IFNA Proteins) type I-dependent protective immunity against primary influenza. (Review)

  5. The IRF7 GG genotype associate with Cognitive Decline and Dementia.

  6. IRF7 cleavage by the 3C protease of enterovirus D68 abrogated its capacity to activate type I interferon (show IFNA Proteins) expression and limit virus replication.

  7. Viral infection induced DAPK1 (show DAPK1 Proteins)-IRF7 and DAPK1 (show DAPK1 Proteins)-IRF3 (show IRF3 Proteins) interactions and overexpression of DAPK1 (show DAPK1 Proteins) enhanced virus-induced activation of the interferon (show IFNA Proteins)-stimulated response element (ISRE) and IFN-beta (show IFNB1 Proteins) promoters and the expression of the IFNB1 (show IFNB1 Proteins) gene.

  8. Interferon regulatory factor 7 (IRF7) is a direct target of miR (show MLXIP Proteins)-762 and overexpression of miR (show MLXIP Proteins)-762 reduced expression of IRF7.

  9. Data indicate that the type-I interferon (show IFNA Proteins) master regulator gene interferon regulatory factor 7 (IRF7) is only hypomethylated in lupus patients with renal involvement.

  10. our results indicate that IRF7 promotes glioma cell invasion and both chemoresistance and radioresistance through AGO2 (show EIF2C2 Proteins) inhibition

Mouse (Murine) Interferon Regulatory Factor 7 (IRF7) interaction partners

  1. MiR (show MLXIP Proteins)-144 reduces the antiviral response by attenuating the TRAF6 (show TRAF6 Proteins)-IRF7 pathway to alter the cellular antiviral transcriptional landscape.

  2. Bcl6 (show BCL6 Proteins), by interacting with the co-factors NcoR2 and HDAC3 (show HDAC3 Proteins), plays a pivotal role in controlling IRF7 induction and antiviral signaling priming.

  3. IRF7 directly binds to the two conserved IRF (show TRIM63 Proteins) binding sites on the USP25 (show USP25 Proteins) promoter to drive transcription of Usp25 (show USP25 Proteins).

  4. poly I:C augments IFN-gamma-induced (show SAMHD1 Proteins) NO production at the transcriptional level via enhanced IRF7 activation

  5. IRF7 protects against vascular smooth muscle cell proliferation.

  6. Data showed that expression of interferon regulatory factor 7 (IRF7) increased during the M2-like to M1-like switch in microglia in vitro and in vivo.

  7. Data suggest that Trim35 (tripartite motif-containing 35 (show TRIM35 Proteins)) down-regulates type I interferon (show IFNA Proteins) production in dendritic cells via toll (show TLR4 Proteins)-like receptors 7/9 and down-regulates stability of Irf7 (interferon regulatory factor 7) via ubiquitination/proteasomes.

  8. Authors show that the capacity to undergo pro- to anti-inflammatory (M1-to-M2) phenotype switch is controlled by the transcription factor interferon regulatory factor 7 (IRF7) that is down-regulated by the TGFbeta1 (show TGFB1 Proteins) pathway.

  9. Our data highlight a pivotal role of CCL7 (show CCL7 Proteins) and IRF-7 in rhinovirus-induced inflammation

  10. These results establish a dominant protective role for MAVS (show MAVS Proteins), IRF-3 (show IRF3 Proteins) and IRF-7, and IFNAR (show IFNAR1 Proteins) in restricting Oropouche virus infection and tissue injury and suggest that IFN signaling in nonmyeloid cells contributes to the host defense.

Pig (Porcine) Interferon Regulatory Factor 7 (IRF7) interaction partners

  1. Expression of porcine fusion protein IRF7/3(5D) efficiently controls foot-and-mouth disease virus replication.

  2. N(pro) of classical swine fever virus (CSFV) interacts with IRF7; Zn-binding domain of N(pro) is essential for the interaction; results show CSFV N(pro) is capable of manipulating function of IRF7 in plasmacytoid dendritic cells

IRF7 Protein Profile

Protein Summary

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Alternative names and synonyms associated with IRF7

  • interferon regulatory factor 7 (irf7)
  • interferon regulatory factor 7 (IRF7)
  • interferon regulatory factor 7 (LOC100358763)
  • interferon regulatory factor 7 (Irf7)
  • IRF-7H protein
  • irf7 protein
  • IRF7A protein
  • IRF7B protein
  • IRF7C protein
  • IRF7H protein
  • wu:fl24c03 protein
  • zgc:66043 protein
  • zgc:77947 protein

Protein level used designations for IRF7

interferon regulatory factor 7 , interferon regulatory factor 7-like , IRF-7 , interferon regulatory factor-7H , interferon regulatory factor-7

393650 Danio rerio
450927 Pan troglodytes
699578 Macaca mulatta
100192336 Salmo salar
100358763 Oryctolagus cuniculus
100405036 Callithrix jacchus
100460542 Pongo abelii
100605304 Nomascus leucogenys
3665 Homo sapiens
54123 Mus musculus
293624 Rattus norvegicus
100037289 Sus scrofa
100125591 Bos taurus
483406 Canis lupus familiaris
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