Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Data show that knockdown of transforming growth factor-activated kinase 1 (TAK1)-binding protein 3 (TAB3) inhibited proliferation of non-small cell lung cancer (NSCLC) cells.
TAB3 regulated ovarian cancer cell bioactivity and chemotherapy performance via the NF-kappaB (show NFKB1 ELISA Kits) pathway.
Upregulation of miR (show MLXIP ELISA Kits)-532-5p and subsequent suppression of the SESTD1 and TAB3 genes represent an antiviral response aimed at limiting West Nile virus infection.
miR (show MLXIP ELISA Kits)-30a in MSCs may participate in the immune dysregulation of the maternal-fetal interface during PE
miR (show MLXIP ELISA Kits)-26b suppresses NF-kappaB (show NFKB1 ELISA Kits) signaling and sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis by inhibiting the expression of TAK1 (show MAP3K7 ELISA Kits) and TAB3.
conclude that TRIM38 (show TRIM38 ELISA Kits) negatively regulates TNFalpha (show TNF ELISA Kits)- and IL-1beta (show IL1B ELISA Kits)-induced signaling by mediating lysosome-dependent degradation of TAB2 (show TAB2 ELISA Kits)/3, two critical components in TNFalpha (show TNF ELISA Kits)- and IL-1beta (show IL1B ELISA Kits)-induced signaling pathways
Studies show that three proteins expressed in HEK (show EPHA3 ELISA Kits)-293T cells (NAP1 (show IL8 ELISA Kits), TANK and TBKBP1 (show TBKBP1 ELISA Kits)) interact with TBK1 (show TBK1 ELISA Kits).
MiR (show MLXIP ELISA Kits)-23b suppresses IL-17 (show IL17A ELISA Kits)-, tumor necrosis factor alpha (TNF-alpha (show TNF ELISA Kits))- or IL-1beta (show IL1B ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation and inflammatory cytokine expression by targeting TAB2 (show TAB2 ELISA Kits), TAB3 and IKK-alpha (show CHUK ELISA Kits).
human TAB2 (show TAB2 ELISA Kits) and TAB3, ubiquitin-chain sensory proteins involved in NF-kappaB (show NFKB1 ELISA Kits) signalling, are directly inactivated by enteropathogenic Escherichia coli NleE, a conserved bacterial type-III-secreted effector responsible for blocking host NF-kappaB (show NFKB1 ELISA Kits) signalling
These results point to the existence of an autophagy-stimulatory 'switch' whereby TAB2 (show TAB2 ELISA Kits) and TAB3 abandon inhibitory interactions with Beclin 1 (show BECN1 ELISA Kits) to engage in a stimulatory liaison with TAK1 (show MAP3K7 ELISA Kits).
Findings indicate that the absence of TAB3 plays a harmful role in ischemic heart disease
TAB2 (show TAB2 ELISA Kits) and TAB3 are essential for B cell activation (show BLNK ELISA Kits) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
TGF-beta activated kinase 1/MAP3K7 binding protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3-like
, NF-kappa-B-activating protein 1
, NFkB activating protein 1
, TAK1-binding protein 3
, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
, TGF-beta-activated kinase 1-binding protein 3
, mitogen-activated protein kinase kinase kinase 7 interacting protein 3
, mitogen activated protein kinase kinase kinase 7 interacting protein 3
, mitogen-activated protein kinase kinase kinase 7-interacting protein 3