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Browse our TAB3 Proteins (TAB3)

Full name:
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 Proteins (TAB3)
On www.antibodies-online.com are 4 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) Proteins from 2 different suppliers available. Additionally we are shipping TAB3 Antibodies (80) and TAB3 Kits (3) and many more products for this protein. A total of 94 TAB3 products are currently listed.
Synonyms:
4921526G09Rik, Map3k7ip3, mKIAA4135, NAP1
list all proteins Gene Name GeneID UniProt
TAB3 257397 Q8N5C8
TAB3 66724 Q571K4

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TAB3 Proteins (TAB3) by Origin

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More Proteins for TAB3 Interaction Partners

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) interaction partners

  1. Upregulation of miR (show MLXIP Proteins)-532-5p and subsequent suppression of the SESTD1 (show SESTD1 Proteins) and TAB3 genes represent an antiviral response aimed at limiting West Nile virus infection.

  2. miR (show MLXIP Proteins)-30a in MSCs may participate in the immune dysregulation of the maternal-fetal interface during PE

  3. miR (show MLXIP Proteins)-26b suppresses NF-kappaB (show NFKB1 Proteins) signaling and sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis by inhibiting the expression of TAK1 (show MAP3K7 Proteins) and TAB3.

  4. conclude that TRIM38 (show TRIM38 Proteins) negatively regulates TNFalpha (show TNF Proteins)- and IL-1beta (show IL1B Proteins)-induced signaling by mediating lysosome-dependent degradation of TAB2 (show TAB2 Proteins)/3, two critical components in TNFalpha (show TNF Proteins)- and IL-1beta (show IL1B Proteins)-induced signaling pathways

  5. Studies show that three proteins expressed in HEK (show EPHA3 Proteins)-293T cells (NAP1 (show IL8 Proteins), TANK and TBKBP1 (show TBKBP1 Proteins)) interact with TBK1 (show TBK1 Proteins).

  6. MiR (show MLXIP Proteins)-23b suppresses IL-17 (show IL17A Proteins)-, tumor necrosis factor alpha (TNF-alpha (show TNF Proteins))- or IL-1beta (show IL1B Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation and inflammatory cytokine expression by targeting TAB2 (show TAB2 Proteins), TAB3 and IKK-alpha (show CHUK Proteins).

  7. human TAB2 (show TAB2 Proteins) and TAB3, ubiquitin-chain sensory proteins involved in NF-kappaB (show NFKB1 Proteins) signalling, are directly inactivated by enteropathogenic Escherichia coli NleE, a conserved bacterial type-III-secreted effector responsible for blocking host NF-kappaB (show NFKB1 Proteins) signalling

  8. These results point to the existence of an autophagy-stimulatory 'switch' whereby TAB2 (show TAB2 Proteins) and TAB3 abandon inhibitory interactions with Beclin 1 (show BECN1 Proteins) to engage in a stimulatory liaison with TAK1 (show MAP3K7 Proteins).

  9. TAB3 is involved in IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation by physically linking TAK1 (show MAP3K7 Proteins) to TRAF6 (show TRAF6 Proteins).

  10. Identification of TAB3 as a binding partner of the protein kinase (show CDK7 Proteins) TAK1 (show MAP3K7 Proteins).

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) interaction partners

  1. TAB2 (show TAB2 Proteins) and TAB3 are essential for B cell activation (show BLNK Proteins) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.

  2. MiR (show MLXIP Proteins)-23b suppresses IL-17 (show IL17A Proteins)-, tumor necrosis factor alpha (TNF-alpha (show TNF Proteins))- or IL-1beta (show IL1B Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation and inflammatory cytokine expression by targeting TAB2 (show TAB2 Proteins), TAB3 and IKK-alpha (show CHUK Proteins).

TAB3 Protein Profile

Protein Summary

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Alternative names and synonyms associated with TAB3

  • TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3)
  • TGF-beta activated kinase 1/MAP3K7 binding protein 3 (Tab3)
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 3-like (MAP3K7IP3)
  • 4921526G09Rik protein
  • Map3k7ip3 protein
  • mKIAA4135 protein
  • NAP1 protein

Protein level used designations for TAB3

TGF-beta activated kinase 1/MAP3K7 binding protein 3 , mitogen-activated protein kinase kinase kinase 7-interacting protein 3-like , NF-kappa-B-activating protein 1 , NFkB activating protein 1 , TAB-3 , TAK1-binding protein 3 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 , TGF-beta-activated kinase 1-binding protein 3 , mitogen-activated protein kinase kinase kinase 7 interacting protein 3 , mitogen activated protein kinase kinase kinase 7 interacting protein 3 , mitogen-activated protein kinase kinase kinase 7-interacting protein 3

GENE ID SPECIES
100018532 Monodelphis domestica
100401610 Callithrix jacchus
100464125 Ailuropoda melanoleuca
100517796 Sus scrofa
100546234 Meleagris gallopavo
100580022 Nomascus leucogenys
257397 Homo sapiens
66724 Mus musculus
491807 Canis lupus familiaris
788288 Bos taurus
790559 Bos taurus
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