Browse our anti-TANK-Binding Kinase 1 (TBK1) Antibodies

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anti-TANK-Binding Kinase 1 Antibodies (TBK1)
On are 157 TANK-Binding Kinase 1 (TBK1) Antibodies from 31 different suppliers available. Additionally we are shipping TANK-Binding Kinase 1 Kits (13) and TANK-Binding Kinase 1 Proteins (9) and many more products for this protein. A total of 189 TANK-Binding Kinase 1 products are currently listed.
1200008B05Rik, AI462036, AW048562, NAK, T2K, TBK1, wu:fk70c05, zgc:136548
list all antibodies Gene Name GeneID UniProt
TBK1 29110 Q9UHD2
TBK1 56480 Q9WUN2
TBK1 299827  

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Top referenced anti-TANK-Binding Kinase 1 Antibodies

  1. Cow (Bovine) Monoclonal TBK1 Primary Antibody for ICC, IF - ABIN252648 : Merimi, Klener, Szynal, Cleuter, Kerkhofs, Burny, Martiat, Van den Broeke: Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code. in Journal of virology 2007 (PubMed)
    Show all 20 references for 252648

  2. Human Polyclonal TBK1 Primary Antibody for EIA, IHC (p) - ABIN360254 : Deng, Shi, Han, Zhong, Li, Li, Hu, Yan, Wang, He, Tang, Deubel, Luo, Ning, Sun: Negative regulation of virus-triggered IFN-beta signaling pathway by alternative splicing of TBK1. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 references for 360254

  3. Human Monoclonal TBK1 Primary Antibody for WB - ABIN967614 : Kishore, Huynh, Mathialagan, Hall, Rouw, Creely, Lange, Caroll, Reitz, Donnelly, Boddupalli, Combs, Kretzmer, Tripp: IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 967614

  4. Cow (Bovine) Polyclonal TBK1 Primary Antibody for WB - ABIN2785953 : Morton, Hesson, Peggie, Cohen: Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma. in FEBS letters 2008 (PubMed)

  5. Human Polyclonal TBK1 Primary Antibody for WB - ABIN151881 : Xie, Zhang, Zhao, Lu, You, Condorelli, Wang, Guan: IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)

More Antibodies against TANK-Binding Kinase 1 Interaction Partners

Zebrafish TANK-Binding Kinase 1 (TBK1) interaction partners

  1. Fish IRF6 (show IRF6 Antibodies) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 (show MYD88 Antibodies) and TBK1, suggesting that differences in the IRF6 (show IRF6 Antibodies) regulation pattern exist between lower and higher vertebrates.

Human TANK-Binding Kinase 1 (TBK1) interaction partners

  1. The occurrence of TBK1 mutations in FTD (show FTL Antibodies) and ALS (show IGFALS Antibodies) underlines the fact that FTD (show FTL Antibodies) and ALS (show IGFALS Antibodies) are part of the same disease spectrum. For future therapeutic trials, characterization of TBK1 mutation carriers in presymptomatic cohorts, such as the genetic frontotemporal dementia initiative (GENFI), is of great importance.

  2. demonstrate a key role of TBK1/IKKepsilon (show IKBKE Antibodies) in the survival and proliferation of HTLV-1-transformed T cells

  3. Data suggest that Encephalomyocarditis virus 3C protease cleaves TANK and disrupts the TANK-TBK1-IKKepsilon (show IKBKE Antibodies)-IRF3 (show IRF3 Antibodies) complex, resulting in reduction in IRF3 (show IRF3 Antibodies) phosphorylation and type I interferon (show IFNA Antibodies) production. (TANK = TRAF family member associated NFKB activator (show TANK Antibodies); TBK1 = TANK binding kinase 1; IKKepsilon (show IKBKE Antibodies) = inhibitor of nuclear factor kappa B kinase subunit epsilon (show IKBKE Antibodies); IRF3 (show IRF3 Antibodies) = interferon regulatory factor 3 (show IRF3 Antibodies))

  4. Data suggest that changes in inhibitor of nuclear factor kappa B kinase subunit epsilon (IKKepsilon (show IKBKE Antibodies)) and TANK-binding kinase 1 (TBK1) expression may be involved in the development of intestinal-type gastric cancer.

  5. Here the authors show that recruitment of WIPI2 (show WIPI2 Antibodies), itself essential for anti-bacterial autophagy, is dependent on the localization of catalytically active TBK1 to the vicinity of cytosolic bacteria.

  6. review of the role of TBK1 in the seemingly unrelated, yet allelic diseases amyotrophic lateral sclerosis (ALS (show IGFALS Antibodies)), frontotemporal dementia (FTD (show FTL Antibodies)), normal tension glaucoma (NTG (show OPA1 Antibodies)) and childhood herpes simplex encephalitis and discuss the role of TBK1 in neuroinflammatory diseases

  7. Enrichment of qualifying variants toward glaucoma was present in all genes except WDR36 (show WDR36 Antibodies), in which controls harbored more variants, and TBK1, in which no qualifying variants were detected in cases or controls.

  8. Human herpesvirus 1 ICP27 interacted with TBK1 and STING in a manner that was dependent on TBK1 activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 pathway in human macrophages.

  9. Upon cytosolic DNA stimulation, STAT3 (show STAT3 Antibodies) Ser (show SIGLEC1 Antibodies)(754) is directly phosphorylated by TBK1 in a STING-dependent manner. Moreover, Ser (show SIGLEC1 Antibodies)(754) phosphorylation inhibits cytosolic DNA-induced STAT3 (show STAT3 Antibodies) transcriptional activity and selectively reduces STAT3 (show STAT3 Antibodies) target genes that are up-regulated in response to cytosolic DNA

  10. YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) act as natural inhibitors of TBK1 and are vital for antiviral physiology.

Mouse (Murine) TANK-Binding Kinase 1 (TBK1) interaction partners

  1. The authors report that Raf kinase inhibitory protein (RKIP (show PEBP1 Antibodies)) is essential for TBK1 activation and type I interferon (show IFNA Antibodies) production triggered by viral infection.

  2. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (show FOSL1 Antibodies) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (show TRAF3 Antibodies)), TIR domain-containing adapter inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies)), and Tank-binding kinase 1 (TBK1) via impairing K63-linked polyubiquitination of TRAF3 (show TRAF3 Antibodies) and TRIF (show RNF138 Antibodies).

  3. TBK1 complexes required for the phosphorylation of IRF3 (show IRF3 Antibodies) and the production of interferon-beta (show IFNB1 Antibodies) have been identified.

  4. this study reveals a previously unknown ICOS (show ICOS Antibodies)-TBK1 signaling pathway that specifies the commitment of germinal center follicular helper T cells

  5. Innate immune responses to adenovirus vectors are largely TBK1-dependent in the spleen but TBK1-independent in the liver

  6. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 Antibodies))-STING membrane protein-TANK-binding kinase 1 (TBK1) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 Antibodies)).

  7. This study suggest that TBK1 exerts pronociceptive effects in inflammatory nociception which are due to both modulation of NF-kappaB dependent genes and regulation of MAPKs and c-fos.

  8. TRIM27 (show RFP Antibodies) inhibits VSV infection-induced type I IFN production by promoting TBK1 degradation.

  9. Suggest that by reducing production of cAMP in adipocytes, PDE3B (show PDE3B Antibodies), IKKepsilon (show IKBKE Antibodies) and TBK1 may contribute to the repression of energy expenditure during obesity.

  10. TBK1 has a role in regulating T-cell activation and migration

TANK-Binding Kinase 1 (TBK1) Antigen Profile

Antigen Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Alternative names and synonyms associated with TANK-Binding Kinase 1 (TBK1)

  • TANK-binding kinase 1 (tbk1) antibody
  • TANK-binding kinase 1 (TBK1) antibody
  • TANK-binding kinase 1 (LOC100358771) antibody
  • TANK-binding kinase 1 (Tbk1) antibody
  • 1200008B05Rik antibody
  • AI462036 antibody
  • AW048562 antibody
  • NAK antibody
  • T2K antibody
  • TBK1 antibody
  • wu:fk70c05 antibody
  • zgc:136548 antibody

Protein level used designations for TBK1

serine/threonine-protein kinase TBK1 , TANK-binding kinase 1 , NF-kappa-B-activating kinase , TANK binding kinase 1 , serine/threonine protein kinase TBK1 , serine/threonine-protein kinase TBK1-like , NF-kB-activating kinase , T2K

446351 Xenopus laevis
452047 Pan troglodytes
692289 Danio rerio
717427 Macaca mulatta
100051650 Equus caballus
100125828 Sus scrofa
100216212 Xenopus (Silurana) tropicalis
100358771 Oryctolagus cuniculus
100399701 Callithrix jacchus
100433568 Pongo abelii
100484104 Ailuropoda melanoleuca
100553575 Anolis carolinensis
100582856 Nomascus leucogenys
29110 Homo sapiens
481145 Canis lupus familiaris
533141 Bos taurus
56480 Mus musculus
299827 Rattus norvegicus
417825 Gallus gallus
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