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Browse our anti-TANK-Binding Kinase 1 (TBK1) Antibodies

Full name:
anti-TANK-Binding Kinase 1 Antibodies (TBK1)
On are 160 TANK-Binding Kinase 1 (TBK1) Antibodies from 30 different suppliers available. Additionally we are shipping TANK-Binding Kinase 1 Kits (10) and TANK-Binding Kinase 1 Proteins (8) and many more products for this protein. A total of 188 TANK-Binding Kinase 1 products are currently listed.
1200008B05Rik, AI462036, AW048562, NAK, T2K, TBK1, wu:fk70c05, zgc:136548
list all antibodies Gene Name GeneID UniProt
TBK1 29110 Q9UHD2
TBK1 56480 Q9WUN2
TBK1 299827  

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Most Popular Reactivities for anti-TANK-Binding Kinase 1 (TBK1) Antibodies

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Top referenced anti-TANK-Binding Kinase 1 Antibodies

  1. Cow (Bovine) Monoclonal TBK1 Primary Antibody for ICC, IF - ABIN252648 : Merimi, Klener, Szynal, Cleuter, Kerkhofs, Burny, Martiat, Van den Broeke: Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code. in Journal of virology 2007 (PubMed)
    Show all 20 references for ABIN252648

  2. Human Polyclonal TBK1 Primary Antibody for EIA, IF - ABIN500308 : Pomerantz, Baltimore: NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. in The EMBO journal 2000 (PubMed)
    Show all 5 references for ABIN500308

  3. Human Polyclonal TBK1 Primary Antibody for EIA, IHC (p) - ABIN360254 : Deng, Shi, Han, Zhong, Li, Li, Hu, Yan, Wang, He, Tang, Deubel, Luo, Ning, Sun: Negative regulation of virus-triggered IFN-beta signaling pathway by alternative splicing of TBK1. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 references for ABIN360254

  4. Human Monoclonal TBK1 Primary Antibody for WB - ABIN967614 : Kishore, Huynh, Mathialagan, Hall, Rouw, Creely, Lange, Caroll, Reitz, Donnelly, Boddupalli, Combs, Kretzmer, Tripp: IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN967614

  5. Human Polyclonal TBK1 Primary Antibody for WB - ABIN2785952 : Morton, Hesson, Peggie, Cohen: Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma. in FEBS letters 2008 (PubMed)

  6. Human Polyclonal TBK1 Primary Antibody for WB - ABIN151881 : Xie, Zhang, Zhao, Lu, You, Condorelli, Wang, Guan: IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)

More Antibodies against TANK-Binding Kinase 1 Interaction Partners

Zebrafish TANK-Binding Kinase 1 (TBK1) interaction partners

  1. Fish IRF6 (show IRF6 Antibodies) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 (show MYD88 Antibodies) and TBK1, suggesting that differences in the IRF6 (show IRF6 Antibodies) regulation pattern exist between lower and higher vertebrates.

Human TANK-Binding Kinase 1 (TBK1) interaction partners

  1. TBK1 duplication is found in normal tension and not in high tension open-angle glaucoma patients of Indian origin.

  2. A broader phenotypic range may be associated with TBK1 copy-number variations, although mutations in this gene are most often detected in patients with normal-tension glaucoma.

  3. Autoubiquitination of TRIM26 (show TRIM26 Antibodies) links TBK1 to NEMO (show IKBKG Antibodies) in RLR (show DHX58 Antibodies)-mediated innate antiviral immune response

  4. ALS (show IGFALS Antibodies)-linked mutations in OPTN (show OPTN Antibodies) and TBK1 can interfere with mitophagy, suggesting that inefficient turnover of damaged mitochondria may represent a key pathophysiological mechanism contributing to neurodegenerative disease.

  5. Mutations in the TBK1 gene were identified to cause amyotrophic lateral sclerosis (ALS)

  6. In combination with phosphorylation of S177 and S513, this posttranslational modification promotes recruitment and retention of OPTN (show OPTN Antibodies)/TBK1 on ubiquitinated, damaged mitochondria

  7. TBK1 should thus also be sequenced, after exclusion of C9orf72 (show C9ORF72 Antibodies) mutation, in patients presenting frontotemporal dementia, particularly in cases secondarily associated with amyotrophic lateral sclerosis

  8. TBK1 carriers with amyotrophic lateral sclerosis had shorter disease duration than carriers with frontotemporal dementia in a Belgian cohort.

  9. The expression of TBK1 in mammalian cell mitosis is reported, including localization of the protein during division and its binding properties.

  10. Optineurin (show OPTN Antibodies) and TANK-binding kinase 1 (TBK1) are transiently recruited to the polyubiquitinated mitochondria, and the activated TBK1 phosphorylates p62 (show GTF2H1 Antibodies) at S403

Mouse (Murine) TANK-Binding Kinase 1 (TBK1) interaction partners

  1. Innate immune responses to adenovirus vectors are largely TBK1-dependent in the spleen but TBK1-independent in the liver

  2. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 Antibodies))-STING membrane protein-TANK-binding kinase 1 (TBK1) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 Antibodies)).

  3. This study suggest that TBK1 exerts pronociceptive effects in inflammatory nociception which are due to both modulation of NF-kappaB dependent genes and regulation of MAPKs and c-fos.

  4. TRIM27 (show RFP Antibodies) inhibits VSV infection-induced type I IFN production by promoting TBK1 degradation.

  5. Suggest that by reducing production of cAMP in adipocytes, PDE3B (show PDE3B Antibodies), IKKepsilon (show IKBKE Antibodies) and TBK1 may contribute to the repression of energy expenditure during obesity.

  6. TBK1 has a role in regulating T-cell activation and migration

  7. findings demonstrate a novel regulatory circuit in which STING and TBK1 reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A (show PPM1A Antibodies) dephosphorylates STING and TBK1

  8. our results identify CK2 (show CSNK2A1 Antibodies) as a novel regulator of TBK1 and IRF3 (show IRF3 Antibodies) and suggest that targeting CK2 (show CSNK2A1 Antibodies) by small molecular inhibitor may be a viable approach to prevent and treat viral infections.

  9. A role for APPL1 (show APPL1 Antibodies) in TLR3 (show TLR3 Antibodies)/4-dependent TBK1 and IKKepsilon (show IKBKE Antibodies) activation in macrophages.

  10. The results highlight the importance of the C-terminal region in the functional activity of IKKepsilon (show IKBKE Antibodies) in innate immune response.Interestingly, corresponding region and residues are not required for activation of downstream signaling by TBK1.

TANK-Binding Kinase 1 (TBK1) Antigen Profile

Antigen Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Alternative names and synonyms associated with TANK-Binding Kinase 1 (TBK1)

  • TANK-binding kinase 1 (tbk1) antibody
  • TANK-binding kinase 1 (TBK1) antibody
  • TANK-binding kinase 1 (LOC100358771) antibody
  • TANK-binding kinase 1 (Tbk1) antibody
  • 1200008B05Rik antibody
  • AI462036 antibody
  • AW048562 antibody
  • NAK antibody
  • T2K antibody
  • TBK1 antibody
  • wu:fk70c05 antibody
  • zgc:136548 antibody

Protein level used designations for TBK1

serine/threonine-protein kinase TBK1 , TANK-binding kinase 1 , NF-kappa-B-activating kinase , TANK binding kinase 1 , serine/threonine protein kinase TBK1 , serine/threonine-protein kinase TBK1-like , NF-kB-activating kinase , T2K

446351 Xenopus laevis
452047 Pan troglodytes
692289 Danio rerio
717427 Macaca mulatta
100051650 Equus caballus
100125828 Sus scrofa
100216212 Xenopus (Silurana) tropicalis
100358771 Oryctolagus cuniculus
100399701 Callithrix jacchus
100433568 Pongo abelii
100484104 Ailuropoda melanoleuca
100553575 Anolis carolinensis
100582856 Nomascus leucogenys
29110 Homo sapiens
481145 Canis lupus familiaris
533141 Bos taurus
56480 Mus musculus
299827 Rattus norvegicus
417825 Gallus gallus
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