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anti-Mouse (Murine) TLR2 Antibodies:
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Mouse (Murine) Monoclonal TLR2 Primary Antibody for Func, IA - ABIN2191804
Meng, Rutz, Schiemann, Metzger, Grabiec, Schwandner, Luppa, Ebel, Busch, Bauer, Wagner, Kirschning: Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. in The Journal of clinical investigation 2004
Show all 6 references for ABIN2191804
Mouse (Murine) Monoclonal TLR2 Primary Antibody for Func, IA - ABIN2191805
Roura-Mir, Wang, Cheng, Matsunaga, Dascher, Peng, Fenton, Kirschning, Moody: Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. in Journal of immunology (Baltimore, Md. : 1950) 2005
Show all 5 references for ABIN2191805
The SNP rs3804099 of TLR2 may have significant effects on heritability of psoriasis vulgaris in Chinese population.
Based on these results, it is possible that expression of porin (show VDAC1 Antibodies) sequence variants that strongly induce TLR2 activation may be a mechanism to enhance the invasive features of pathogenic Neisseriae strains.
TLR2 polymorphisms were associated with recurrent acute otitis media.
this study shows that an increase in CD14 (show NDUFA2 Antibodies)+ TLR-2+ monocytes within the 90 days post-transplantation was associated with increased risk of kidney allograft dysfunction at 180 and 365 days post-transplantation
analysis of TLR2, TLR4 (show TLR4 Antibodies) and TLR9 (show TLR9 Antibodies) genes and their significance as biological markers in patients with B-cell chronic lymphocytic leukemia
TLR-stimulated pancreatic cancer cells were specifically investigated for activated signaling pathways of VEGF (show VEGFA Antibodies)/PDGF (show PDGFA Antibodies) and anti-apoptotic Bcl-xL (show BCL2L1 Antibodies) expression as well as tumor cell growth.
Data indicate beta-D-mannuronic acid (M2000) inhibitory effect on Toll (show TLR4 Antibodies)-like receptors TLR2 and TLR4 (show TLR4 Antibodies) signalling in HEK293 cells.
review article explores the main roles played by TLR2 in the pathogenesis of chronoinflammaging in patients suffering from AD
TLR2, Tim1 (show ARHGEF5 Antibodies), Tim3 (show HAVCR2 Antibodies), TNF-alpha (show TNF Antibodies), IgE and EOS (show IKZF4 Antibodies) play a role in Mycoplasma pneumoniae Pneumonia-related wheezing in children.
In conclusion, TLR2 plays an even more important role than TLR4 (show TLR4 Antibodies) not only in recognizing Helicobacter pylori, but also in the induction of inflammatory cytokines initiated by Helicobacter pylori.
These results point out to a role of TLR2 in gut (show GUSB Antibodies) protection against colonization and endogenous invasion by Candida albicans.
Paeoniflorin inhibits high glucose-induced macrophage activation through TLR2-dependent signal pathways.
Data, including data from studies using knockout mice, suggest that signaling via Tlr2 is involved in inflammatory response induced by Bothrops atrox snake venom.
These results suggested the importance of TRIF (show RNF138 Antibodies) in TLR2 mediated foam cell formation via inflammatory mediators, including MCP-1 (show CPT1B Antibodies).
this study shows that probiotic Lactobacillus casei Lbs2 ameliorates experimental colitis through Toll-like receptor 2-dependent immunomodulation
PHLDA1 (show PHLDA1 Antibodies) plays a critical role in the development of progressive lung contusion and subsequent inflammation.
postnatal expression of TLR2 and TLR4 (show TLR4 Antibodies) in small intestinal epithelial cells
TLR2 deletion induced activation of the renin (show REN Antibodies) angiotensin system in ureteral obstructed kidneys. Inhibition of both RAS and TLR2 had an additive ameliorative effect on UUO injury of the kidney.
this study produced a new antibody against the specific extracellular domain of TLR2 which has protective effect on TLR2 agonists-driven inflammatory and allergic response.
results suggest that HMGB1 (show HMGB1 Antibodies) mediates cell proliferation through a novel mechanism that involves TLR2, FoxO1 (show FOXO1 Antibodies) nuclear importation and PCNA (show PCNA Antibodies) overexpression
Transcription levels of TLR2, TLR4 (show TLR4 Antibodies), and CD14 (show CD14 Antibodies) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
We structurally defined with 5'-RACE experiments three promoters (P1-3) controlling TLR2 expression in udder, liver and other tissues of cows suffering from E. coli mastitis.
TLR2 and TLR4 (show TLR4 Antibodies) mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.
positive correlation between lower neutrophil apoptosis and higher expression of TLR2 and TLR4 (show TLR4 Antibodies) with the formation of NETs and change in surface architecture.
TLR2, TLR1 (show TLR1 Antibodies), and TLR6 (show TLR6 Antibodies) haev roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides by epithelial and stromal cells of bovine endometrium
Data suggest that granulosa cells from dominant follicles express functional TLR2 and TLR4 (show TLR4 Antibodies); granulosa cells appear to participate in innate immunity by responding to bacterial lipopolysaccharides/lipopeptides via TLR2 and TLR4 (show TLR4 Antibodies) signaling pathways.
The expressions of host TLR2 and 4 genes were significantly higher in acidosis-resistant steers compared to those in acidosis-susceptible steers.
Whereas previous results regarding the TLR1 (show TLR1 Antibodies) gene were not corroborated, a risk haplotype was detected in TLR2; however, its low frequency indicates that this detected association should be interpreted with caution.
The identification of antibodies specific for bovine and ovine TLR2 will facilitate studies of the role of this important pattern recognition receptors in the initiation of immune responses to important pathogens.
ALOX5AP (show ALOX5AP Antibodies), CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2, TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.
Lipopolysaccharide upregulates the expression of rabbit TLR2 and 4 in the uterine body and horn, and the expression of TLR4 (show TLR4 Antibodies) in the ovary.
VB-201 may counter inflammation where TLR-2 and/or CD14 (show CD14 Antibodies) complicity is essential, and is therefore beneficial for the treatment of atherosclerosis.
Toll-like receptor 2 signaling on intestinal epithelial cells may enhance intestinal barrier function and prevent deoxynivalenol-induced barrier dysfunction of epithelial cells.
These results suggest that porcine circovirus 2 induces IL-8 (show IL8 Antibodies) secretion via the TLR2/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signalling pathway.
At 14 days after autotransplantation of a pig kidney, mRNA expression for TLR2 is increased.
These data demonstrated that TLR2, TLR3 (show TLR3 Antibodies) and TLR9 (show TLR9 Antibodies) contribute to NF-kappaB (show NFKB1 Antibodies) activation in response to porcine epidemic diarrhea virus infection, but not RIG-I (show DDX58 Antibodies).
Data suggest TLR2, TLR4 (show TLR4 Antibodies), and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2/TLR4 (show TLR4 Antibodies).
TLR2 is required for the suppression of TLR4 (show TLR4 Antibodies) signaling activation.
The role of TLR2, TLR4 (show TLR4 Antibodies) and RP105 (show CD180 Antibodies)/MD1 (show LY86 Antibodies) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Antibodies), is reported.
Single nucleotide polymorphisms in TLR2 is associated with immune response to gram-negative bacterial infections.
The dramatic reduction in p38 MAPK (show MAPK14 Antibodies) phosphorylation by TLR-2 stimulation in aortic valve interstitial cells excludes a role for this receptor type in mediating angiotensin II or peroxynitrite effects.
In total, 20, 27, and 26 SNPs were detected in TLR1 (show TLR1 Antibodies), TLR2, and TLR6 (show TLR6 Antibodies), respectively; in TLR1 (show TLR1 Antibodies) and TLR2, the numbers of SNPs detected were significantly lower (P < or = 0.05, P < or = 0.01) in the wild boars than in the domestic pigs.
expression of TLR4 (show TLR4 Antibodies) and TLR2 in normal and LPS (show IRF6 Antibodies)-treated horses
Over-expression of TLR2 decreases radical damage to host cells through low-level production of NO and MDA and promotes the clearance of invasive bacteria by up-regulating lysozyme (show LYZ Antibodies) secretion and filtration of inflammatory cells to the infected site.
TLR2 of M. fuscata has undergone purifying selection while the membrane-proximal part of the extracellular domain of M. mulatta TLR2 exhibits higher rates of non-synonymous substitutions, indicating a trace of Darwinian positive selection
The results indicate that microglia and astrocytes respond to B (show TDO2 Antibodies). burgdorferi through TLR1 (show TLR1 Antibodies)/2 and TLR5 (show TLR5 Antibodies).
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
toll/interleukin 1 receptor-like 4
, toll/interleukin-1 receptor-like protein 4
, toll-like receptor 2 variant 1
, toll-like receptor 2 variant 2
, toll-like receptor 2 type-2
, toll-like receptor 2 type2
, Toll-like receptor 2-like protein