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Browse our anti-TLR4 (TLR4) Antibodies

Full name:
anti-Toll-Like Receptor 4 Antibodies (TLR4)
On www.antibodies-online.com are 419 Toll-Like Receptor 4 (TLR4) Antibodies from 32 different suppliers available. Additionally we are shipping TLR4 Kits (53) and TLR4 Proteins (20) and many more products for this protein. A total of 507 TLR4 products are currently listed.
Synonyms:
ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLL

All available anti-TLR4 Antibodies

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Top referenced anti-TLR4 Antibodies

  1. Mouse (Murine) Polyclonal TLR4 Primary Antibody for WB - ABIN388334 : de Groot, Hoefer, Grundmann, Schoneveld, Haverslag, van Keulen, Bot, Timmers, Piek, Pasterkamp, de Kleijn: Arteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cells. in Journal of molecular and cellular cardiology 2011 (PubMed)
    Show all 6 references for ABIN388334

  2. Cow (Bovine) Polyclonal TLR4 Primary Antibody for IF (cc), IF (p) - ABIN736491 : Tang, Zhou, Wang, Zhang, Wang, Li, Huang: Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts. in Archives of oral biology 2011 (PubMed)
    Show all 6 references for ABIN736491

  3. Human Polyclonal TLR4 Primary Antibody for DB, EIA - ABIN493502 : Zhang, Shan, Jiang, Cohn, Lee: Toll-like receptor 4 deficiency causes pulmonary emphysema. in The Journal of clinical investigation 2006 (PubMed)
    Show all 5 references for ABIN493502

  4. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS, IP - ABIN1449233 : Fuller, Bayley, Chambers: Activin A is an essential cofactor for osteoclast induction. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 4 references for ABIN1449233

  5. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN2853611 : Tsutsumi-Ishii, Nagaoka: Modulation of human beta-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN2853611

  6. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN1449236 : Kawasaki, Nogawa, Nishijima et al.: Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 ... in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for ABIN1449236

  7. Human Polyclonal TLR4 Primary Antibody for EIA, WB - ABIN951278 : Sam-Agudu, Greene, Opoka, Kazura, Boivin, Zimmerman, Riedesel, Bergemann, Schimmenti, John: TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria. in The American journal of tropical medicine and hygiene 2010 (PubMed)
    Show all 3 references for ABIN951278

  8. Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN119333 : Jiang, Akashi, Miyake, Petty: Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 2 references for ABIN119333

  9. Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN119329 : Shimazu, Akashi, Ogata, Nagai, Fukudome, Miyake, Kimoto: MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. in The Journal of experimental medicine 1999 (PubMed)
    Show all 2 references for ABIN119329

  10. Human Polyclonal TLR4 Primary Antibody for EIA, IF - ABIN500952 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)
    Show all 2 references for ABIN500952

More Antibodies against TLR4 Interaction Partners

Human Toll-Like Receptor 4 (TLR4) interaction partners

  1. Our data suggested that MIF (show AMH Antibodies) affected the intrinsic properties of tumors and the host immune response in tumor microenvironment by regulating the TLR4/HMGB1 (show HMGB1 Antibodies) axis, leading to metastasis of breast cancer

  2. an association between TLR4 rs10759931 polymorphism (OR = 0.086, CI: 0.04-0.18, P = <0.00001)and colon cancer; the rs2770150 polymorphism is associated with colon cancer in women aged over 50 years.

  3. expression and activity of TLR2 (show TLR2 Antibodies) and 4 in peripheral blood monocytes as well as B cells in in type-2 diabetic subjects; surface expression of TLR2 (show TLR2 Antibodies) and 4 was significantly reduced in B cells of the newly diagnosed type-2 diabetic subjects and was associated with decreased cellular activation and cytokine secretion

  4. PAUF mediated dendritic cell activation and immune stimulation are dependent on TLR4

  5. TLR4 signaling initiates microglial IL-6 (show IL6 Antibodies) secretion through glioma stem cells, not bulk glioma cells.

  6. Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK (show MAPK1 Antibodies) activation

  7. TAK (show CDK9 Antibodies)-242 also significantly suppressed the expression of TLR4, MyD88 (show MYD88 Antibodies) and the activation of NF-kappaB (show NFKB1 Antibodies) in lungs, suggesting that TAK (show CDK9 Antibodies)-242-mediated inhibition occurred largely through the TLR4/NF-kappaB (show NFKB1 Antibodies) signal pathway.

  8. PRG4 (show PRG4 Antibodies) binds to TLR2 (show TLR2 Antibodies) and TLR4 and this binding mediates a novel anti-inflammatory role for PRG4 (show PRG4 Antibodies)

  9. Suggest an essential role of TLR4-Src (show SRC Antibodies) signaling in macrophages in the pathogenesis of atherosclerosis.

  10. This study describes a novel posttranslational regulation of the HOIP (show RNF31 Antibodies)-containing linear-ubiquitin-chain assembly complex (LUBAC)-mediated linear ubiquitination that is critical for specifically directing TLR4-mediated NF-kappaB (show NFKB1 Antibodies) activation.

Mouse (Murine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. HMGB1 (show HMGB1 Antibodies)-TLR2 (show TLR2 Antibodies)/TLR4 signaling cascade.

  2. ProTalpha preconditioning-induced prevention of retinal ischemic damage is mediated by selective activation of the TIR-domain-containing adapter-inducing interferon-beta (show IFNB1 Antibodies) interferon regulatory factor 3 (show IRF3 Antibodies) pathway downstream of toll-like receptor 4 in microglia

  3. in microglia, activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) down-regulates miR (show MLXIP Antibodies)-26a

  4. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of beta-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor kappaB (NFkappaB) Activation.

  5. Heat shock protein 60 (show HSPD1 Antibodies) stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK (show MAPK1 Antibodies) activation

  6. Results demonstrate a selective regulation of TLR4 signaling by EGFR (show EGFR Antibodies) and highlight the potential use of EGFR (show EGFR Antibodies) inhibitors to treat septic shock syndrome.

  7. THe results of this study suggested that enhanced glial TLR4 signalling during disease progression contributes to end-stage ALS pathology in hSOD1 (show SOD1 Antibodies)(G93A) mice.

  8. These results evidence the versatility of neuroimaging techniques to monitor the role of toll-like receptor 4 after cerebral ischemia

  9. These results expand on our knowledge of the roles for TLR2 (show TLR2 Antibodies) and TLR4 in C. burnetii infection and suggest various roles for these receptors that are dictated by the site of infection.

  10. Suggest an essential role of TLR4-Src (show SRC Antibodies) signaling in macrophages in the pathogenesis of atherosclerosis.

Cow (Bovine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.

  2. TLR2 (show TLR2 Antibodies) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  3. TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins

  4. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (show TLR2 Antibodies) and TLR4 with the formation of NETs and change in surface architecture.

  5. Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (show CCL2 Antibodies)) genes.

  6. Studied bovine TLR4 gene in mastitis resistance by association as well as expression profiling analysis in crossbred cattle.

  7. Findings indicate that intervertebral disc (IVD (show IVD Antibodies)) cells constitutively express TLR4.

  8. Data suggest that granulosa cells from dominant follicles express functional TLR2 (show TLR2 Antibodies) and TLR4; granulosa cells appear to participate in innate immunity by responding to bacterial lipopolysaccharides/lipopeptides via TLR2 (show TLR2 Antibodies) and TLR4 signaling pathways.

  9. The expressions of host TLR2 (show TLR2 Antibodies) and 4 genes were significantly higher in acidosis-resistant steers compared to those in acidosis-susceptible steers.

  10. TLR4 and downstream adaptor molecules, transcription factors and cytokines were up-regulated when endometrial epithelial cells were stimulated with LPS (show IRF6 Antibodies)

Rabbit Toll-Like Receptor 4 (TLR4) interaction partners

  1. The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (show NFKB1 Antibodies) (p65 (show SYT1 Antibodies)) were respectively detected.

  2. Lipopolysaccharide upregulates the expression of rabbit TLR2 (show TLR2 Antibodies) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.

  3. Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (show NFKB1 Antibodies) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (show ICAM1 Antibodies).

  4. TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage

  5. The elevated expression of TLR4 was detected after SAH (show ACSM3 Antibodies) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (show ACSM3 Antibodies).

Pig (Porcine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (show IRF6 Antibodies) challenge.

  2. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.

  3. Data suggest TLR2 (show TLR2 Antibodies), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (show TLR2 Antibodies)/TLR4.

  4. TLR2 (show TLR2 Antibodies) is required for the suppression of TLR4 signaling activation.

  5. The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.

  6. The role of TLR2 (show TLR2 Antibodies), TLR4 and RP105 (show CD180 Antibodies)/MD1 (show LY86 Antibodies) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Antibodies), is reported.

  7. Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.

  8. Fish Oil attenuates the activation of the HPA (show HPSE Antibodies) axis induced by LPS (show IRF6 Antibodies) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.

  9. Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.

  10. The complete coding sequence of TLR4 gene in Min pig and 3 variants with single point mutations were obtained.

Horse (Equine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. A low steady expression of TLR4, MD-2 (show LY96 Antibodies) and CD14 (show CD14 Antibodies) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.

  2. In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.

  3. evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins

  4. TLR4/MD-2 (show LY96 Antibodies) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.

TLR4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TLR4

  • toll-like receptor 4 (TLR4) antibody
  • toll-like receptor 4 (Tlr4) antibody
  • ARMD10 antibody
  • CD284 antibody
  • Lps antibody
  • Ly87 antibody
  • Ran/M1 antibody
  • Rasl2-8 antibody
  • TLR-4 antibody
  • TOLL antibody

Protein level used designations for TLR4

hToll , homolog of Drosophila toll , lipopolysaccharide response , toll4 , Toll-like receptor4 protein , Toll-like receptor 4-like protein

GENE ID SPECIES
7099 Homo sapiens
21898 Mus musculus
417241 Gallus gallus
29260 Rattus norvegicus
281536 Bos taurus
100009497 Oryctolagus cuniculus
100724803 Cavia porcellus
403417 Canis lupus familiaris
399541 Sus scrofa
493698 Felis catus
100066890 Equus caballus
100860955 Capra hircus
554263 Ovis aries
100980644 Pan paniscus
100689329 Cricetulus griseus
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