Browse our anti-TLR4 (TLR4) Antibodies

Full name:
anti-Toll-Like Receptor 4 Antibodies (TLR4)
On www.antibodies-online.com are 600 Toll-Like Receptor 4 (TLR4) Antibodies from 37 different suppliers available. Additionally we are shipping TLR4 Kits (54) and TLR4 Proteins (21) and many more products for this protein. A total of 690 TLR4 products are currently listed.
Synonyms:
ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLL

All available anti-TLR4 Antibodies

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Top referenced anti-TLR4 Antibodies

  1. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS, IP - ABIN252516 : Jung, Lee, Jung, Ock, Lee, Lee, Suk: TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 11 references for 252516

  2. Mouse (Murine) Polyclonal TLR4 Primary Antibody for WB - ABIN388334 : de Groot, Hoefer, Grundmann, Schoneveld, Haverslag, van Keulen, Bot, Timmers, Piek, Pasterkamp, de Kleijn: Arteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cells. in Journal of molecular and cellular cardiology 2011 (PubMed)
    Show all 6 references for 388334

  3. Human Polyclonal TLR4 Primary Antibody for DB, EIA - ABIN493502 : Zhang, Shan, Jiang, Cohn, Lee: Toll-like receptor 4 deficiency causes pulmonary emphysema. in The Journal of clinical investigation 2006 (PubMed)
    Show all 5 references for 493502

  4. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS, IP - ABIN1449233 : Fuller, Bayley, Chambers: Activin A is an essential cofactor for osteoclast induction. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 4 references for 1449233

  5. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN1449236 : Kawasaki, Nogawa, Nishijima et al.: Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 ... in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for 1449236

  6. Human Polyclonal TLR4 Primary Antibody for EIA, WB - ABIN951278 : Sam-Agudu, Greene, Opoka, Kazura, Boivin, Zimmerman, Riedesel, Bergemann, Schimmenti, John: TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria. in The American journal of tropical medicine and hygiene 2010 (PubMed)
    Show all 3 references for 951278

  7. Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN119329 : Jiang, Akashi, Miyake, Petty: Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 2 references for 119329

  8. Human Monoclonal TLR4 Primary Antibody for FACS - ABIN4896796 : Punsmann, Liebers, Lotz, Brüning, Raulf: Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. in PLoS ONE 2013 (PubMed)
    Show all 2 references for 4896796

  9. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN4897001 : Wang, Ma, Charboneau, Barke, Roy: Morphine inhibits murine dendritic cell IL-23 production by modulating Toll-like receptor 2 and Nod2 signaling. in The Journal of biological chemistry 2011 (PubMed)

  10. Human Monoclonal TLR4 Primary Antibody for FACS - ABIN4896792 : Donnadieu-Rigole, Mura, Portales, Duroux-Richard, Bouthier, Eliaou, Perney, Apparailly: Effects of alcohol withdrawal on monocyte subset defects in chronic alcohol users. in Journal of leukocyte biology 2016 (PubMed)

More Antibodies against TLR4 Interaction Partners

Human Toll-Like Receptor 4 (TLR4) interaction partners

  1. these findings identify new compounds for antagonizing TLR2 (show TLR2 Antibodies) and TLR4 activation and define structural properties of POPG analogs for discriminating between two TLR systems.

  2. Compared to adipocytes from the infrapatellar fat pad (show PADI4 Antibodies) (IPFP) and synovium of lean patients, adipocytes from the IPFP of obese patients had higher levels of TLR4 gene expression.

  3. These new findings reveal the ability of RvD2 to reduce TLR4 expression and attenuate LPS (show IRF6 Antibodies)-induced inflammation, providing a new area of SPM (show NPC1 Antibodies) activity to investigate in this major area of therapeutic research.

  4. The present study demonstrated that plasma fatty acid can interact with variants of the TLR4 gene to modulate the risk for a systemic inflammatory state represented by the inflammatory cluster, as measured by 11 inflammatory biomarker plasma concentrations.

  5. Smoking can induce differential expression of circulating miR (show MLXIP Antibodies)-NAs (show SCN9A Antibodies), such as down-regulation of miR (show MLXIP Antibodies)-149-3p. Reducing miR (show MLXIP Antibodies)-149-3p may increase the inflammatory response in COPD (show ARCN1 Antibodies) patients through the regulation of the TLR-4/NF-kappaB (show NFKB1 Antibodies) signaling pathway

  6. HDL (show HSD11B1 Antibodies) isolated from patients with metabolic syndrome induced macrophage apoptosis, oxidative stress, and CHOP (show DDIT3 Antibodies) upregulation, which were blocked by PBA and DPI (show DSP Antibodies). These data indicate that ox-HDL (show HSD11B1 Antibodies) may activate ER stress-CHOP (show DDIT3 Antibodies)-induced apoptotic pathway in macrophages via enhanced oxidative stress and that this pathway may be mediated by TLR4.

  7. The current study discovered a novel 72-kDa chondroitin sulfate-OGN (show OGN Antibodies) that is specific for innate immune cells. This variant is able to bind and activate TLR4.

  8. the coding regions of 17 genes involved in the regulation of the immune response were determined by massive parallel sequencing. The analysis revealed 39 nonsynonymous SNPs that lead to amino acid substitutions, including the following informative genetic markers: PTPN22 (show PTPN22 Antibodies) c.1858C>T (rs2476601), TLR4 c.896A>G (rs4986790) and TLR4 c.1196C>T (rs4986791), IL7R (show IL7R Antibodies) c.197T>C (rs1494555) and IL7R (show IL7R Antibodies) c.412G>A (rs1494558).

  9. This study suggest that TLR4 gene polymorphism may act as an intermediate factor for the association between tobacco smoking addiction and bipolar disorder.

  10. On stimulation with the TLR4 agonist, LPS (show IRF6 Antibodies) downregulated TLR4 mRNA expression in alveolar macrophages.

Mouse (Murine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Data suggest that the transmembrane domains of Tlr4 and Tlr6 (show TLR6 Antibodies) have essential roles in Tlr4/Tlr6 (show TLR6 Antibodies)/Cd36 (show CD36 Antibodies) receptor multimerization and activation; disruption of receptor multimerization (here, using a recombinant peptide fragment from Tlr4 transmembrane domain) reduces secretion of proinflammatory mediators from microglia and ultimately rescues neurons from death.

  2. This study demonstrated that TLR4 deficiency contributes to regulating microglia to switch to the M2 phenotype, which ameliorates neurological impairment after traumatic brain injury in mice.

  3. Ggut dysbiosis with simultaneous leaky gut (show GUSB Antibodies) and systemic endotoxemia-induced TLR4 activation.

  4. The current study discovered a novel 72-kDa chondroitin sulfate-OGN (show OGN Antibodies) that is specific for innate immune cells. This variant is able to bind and activate TLR4.

  5. results strongly implicate the HMGB1 (show HMGB1 Antibodies)-TLR2 (show TLR2 Antibodies)/4 axis in the activation of microglia following multiple cortical spreading depression inductions

  6. Inflammatory polarization of cardiac mesenchymal stromal cells by left ventricular dysfunction is mediated by TLR4.

  7. TLR4 signaling mediates benzanthrone-induced inflammation.

  8. These findings illustrate the critical role of pulmonary TLR4 in the development of necrotizing enterocolitis -associated lung injury

  9. TRIF (show RNF138 Antibodies) has a central role in sterile liver injury in mouse model.

  10. IL-10 (show IL10 Antibodies) helps to maintain heart function during stress via myeloid differentiation gene 88/IRAK-4 (show IRAK4 Antibodies)/IRAK-1 (show IRAK1 Antibodies)-dependent TLR4 signaling.

Cow (Bovine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. TLR4 polymorphisms are associated with lower reproductive Performance.

  2. As a pilot study, the present results revealed that identified SNPs in IL8 (show IL8 Antibodies) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.

  3. Transcription levels of TLR2 (show TLR2 Antibodies), TLR4, and CD14 (show CD14 Antibodies) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.

  4. Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.

  5. TLR2 (show TLR2 Antibodies) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  6. TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins

  7. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (show TLR2 Antibodies) and TLR4 with the formation of NETs and change in surface architecture.

  8. Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (show CCL2 Antibodies)) genes.

  9. Studied bovine TLR4 gene in mastitis resistance by association as well as expression profiling analysis in crossbred cattle.

  10. Findings indicate that intervertebral disc (IVD (show IVD Antibodies)) cells constitutively express TLR4.

Rabbit Toll-Like Receptor 4 (TLR4) interaction partners

  1. TLR2 (show TLR2 Antibodies), 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.

  2. The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (show NFKB1 Antibodies) (p65 (show SYT1 Antibodies)) were respectively detected.

  3. Lipopolysaccharide upregulates the expression of rabbit TLR2 (show TLR2 Antibodies) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.

  4. Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (show NFKB1 Antibodies) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (show ICAM1 Antibodies).

  5. TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage

  6. The elevated expression of TLR4 was detected after SAH (show ACSM3 Antibodies) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (show ACSM3 Antibodies).

Pig (Porcine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (show MAMLD1 Antibodies) in Meishan weaned piglets.

  2. Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (show IRF6 Antibodies) challenge.

  3. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.

  4. Data suggest TLR2 (show TLR2 Antibodies), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (show TLR2 Antibodies)/TLR4.

  5. TLR2 (show TLR2 Antibodies) is required for the suppression of TLR4 signaling activation.

  6. The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.

  7. The role of TLR2 (show TLR2 Antibodies), TLR4 and RP105 (show CD180 Antibodies)/MD1 (show LY86 Antibodies) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Antibodies), is reported.

  8. Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.

  9. Fish Oil attenuates the activation of the HPA (show HPSE Antibodies) axis induced by LPS (show IRF6 Antibodies) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.

  10. Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.

Horse (Equine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.

  2. A low steady expression of TLR4, MD-2 (show LY96 Antibodies) and CD14 (show CD14 Antibodies) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.

  3. In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.

  4. evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins

  5. TLR4/MD-2 (show LY96 Antibodies) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.

TLR4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TLR4

  • toll-like receptor 4 (TLR4) antibody
  • toll-like receptor 4 (Tlr4) antibody
  • ARMD10 antibody
  • CD284 antibody
  • Lps antibody
  • Ly87 antibody
  • Ran/M1 antibody
  • Rasl2-8 antibody
  • TLR-4 antibody
  • TOLL antibody

Protein level used designations for TLR4

hToll , homolog of Drosophila toll , lipopolysaccharide response , toll4 , Toll-like receptor4 protein , Toll-like receptor 4-like protein

GENE ID SPECIES
7099 Homo sapiens
21898 Mus musculus
417241 Gallus gallus
29260 Rattus norvegicus
281536 Bos taurus
100009497 Oryctolagus cuniculus
100724803 Cavia porcellus
403417 Canis lupus familiaris
399541 Sus scrofa
493698 Felis catus
100066890 Equus caballus
100860955 Capra hircus
554263 Ovis aries
100980644 Pan paniscus
100689329 Cricetulus griseus
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