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Browse our anti-TLR4 (TLR4) Antibodies

Full name:
anti-Toll-Like Receptor 4 Antibodies (TLR4)
On www.antibodies-online.com are 579 Toll-Like Receptor 4 (TLR4) Antibodies from 34 different suppliers available. Additionally we are shipping TLR4 Kits (46) and TLR4 Proteins (20) and many more products for this protein. A total of 660 TLR4 products are currently listed.
Synonyms:
ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLL

All available anti-TLR4 Antibodies

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Top referenced anti-TLR4 Antibodies

  1. Human Polyclonal TLR4 Primary Antibody for ICC, FACS - ABIN252535 : Medzhitov, Preston-Hurlburt, Janeway: A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. in Nature 1997 (PubMed)
    Show all 13 references for ABIN252535

  2. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS, IP - ABIN252516 : Jung, Lee, Jung, Ock, Lee, Lee, Suk: TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 11 references for ABIN252516

  3. Mouse (Murine) Polyclonal TLR4 Primary Antibody for WB - ABIN388334 : de Groot, Hoefer, Grundmann, Schoneveld, Haverslag, van Keulen, Bot, Timmers, Piek, Pasterkamp, de Kleijn: Arteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cells. in Journal of molecular and cellular cardiology 2011 (PubMed)
    Show all 6 references for ABIN388334

  4. Human Polyclonal TLR4 Primary Antibody for DB, EIA - ABIN493502 : Zhang, Shan, Jiang, Cohn, Lee: Toll-like receptor 4 deficiency causes pulmonary emphysema. in The Journal of clinical investigation 2006 (PubMed)
    Show all 5 references for ABIN493502

  5. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS, IP - ABIN1449233 : Fuller, Bayley, Chambers: Activin A is an essential cofactor for osteoclast induction. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 4 references for ABIN1449233

  6. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN2853611 : Tsutsumi-Ishii, Nagaoka: Modulation of human beta-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN2853611

  7. Mouse (Murine) Monoclonal TLR4 Primary Antibody for FACS - ABIN1449236 : Kawasaki, Nogawa, Nishijima et al.: Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 ... in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for ABIN1449236

  8. Human Polyclonal TLR4 Primary Antibody for EIA, WB - ABIN951278 : Sam-Agudu, Greene, Opoka, Kazura, Boivin, Zimmerman, Riedesel, Bergemann, Schimmenti, John: TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria. in The American journal of tropical medicine and hygiene 2010 (PubMed)
    Show all 3 references for ABIN951278

  9. Human Polyclonal TLR4 Primary Antibody for EIA, IF - ABIN500952 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)
    Show all 2 references for ABIN500952

  10. Dog (Canine) Monoclonal TLR4 Primary Antibody for FACS - ABIN119329 : Jiang, Akashi, Miyake, Petty: Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 2 references for ABIN119329

More Antibodies against TLR4 Interaction Partners

Human Toll-Like Receptor 4 (TLR4) interaction partners

  1. we report that exogenous CnB (show PPP3R1 Antibodies) is taken up by cells in a time- and concentration-dependent manner via clathrin-dependent receptor-mediated internalization. Our findings further confirm that uptake is mediated by the TLR4/MD2 (show LY96 Antibodies) complex together with the co-receptor CD14 (show NDUFA2 Antibodies)

  2. TLR4 siRNA inhibits cell proliferation, migration and invasion by suppressing ACAT1 (show ACAT1 Antibodies) expression, suggesting that TLR4 may be a potential therapeutic target for the treatment of colorectal cancer

  3. No difference was found between Turkish rheumatoid arthritis patient and control groups with regard to TLR-4 expression.

  4. A significant difference was found between the levels of staining of TLR-2 (show TLR2 Antibodies), TLR-4 and hBD-1 (show DEFB1 Antibodies) in different lesions from the epidermis, inflammation region, dermis and skin appendages (p < 0.05) in patients with acne vulgaris.

  5. Apocynin appears to attenuate the lipopolysaccharide-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor-4-mediated activation of the Akt (show AKT1 Antibodies), mTOR (show FRAP1 Antibodies), and NF-kappaB (show NFKB1 Antibodies) pathways.

  6. High TLR4 expression is associated with hepatocellular carcinoma.

  7. Polymorphisms of TLR4 in Porphyromonas gingivalis carriers seem to expose to alveolar bone loss.

  8. We investigated the association of single-nucleotide polymorphisms in TLR4 and CD14 (show NDUFA2 Antibodies) and carotid intima-media thickness, a surrogate measurement for CVD, in HIV-infected individuals on antiretroviral therapy and HIV-uninfected controls.

  9. Lentivirus-mediated RNA interference effectively silenced TLR4 expression in HLEC cells, which decelerated their proliferation rate and extended the cell cycle.

  10. TLR-2 (show TLR2 Antibodies), TLR-4, and TLR-9 (show TLR9 Antibodies) were expressed in primary tumors, neck metastases as well as in recurrent tumors of OTSCC. Thus, these receptors seem to play a role in both the development and progression of tongue carcinoma. These TLRs may also contribute to the invasive potential of OTSCC.

Mouse (Murine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Wild-type and TLR4-deficient mice showed different brain biochemical response in MPTP (show PTPN2 Antibodies) poisoning.

  2. The results suggested that the relieving effect of KGLY against LPS-induced ALI might be partially due to suppression of oxidative stress and inflammatory response, inhibition of TLR4-mediated NF-kappaB (show NFKB1 Antibodies) activation, and down-regulation of MMP9 (show MMP9 Antibodies) expression, indicating it may be a potential therapeutic agent for ALI.

  3. Neuroprotective effects of oleoylethanolamide on cerebral ischemia may be attributed to its antiapoptotic property achieved, at least in part, through the PPARalpha (show PPARA Antibodies) signaling and inhibition of both TLR4/NF-kappaB (show NFKB1 Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.

  4. TLR4 ablation alleviated paraquat-induced myocardial contractile dysfunction possibly through attenuation of ER stress, apoptosis and inflammation.

  5. TLR4 knockout alleviated paraquat-induced cardiac dysfunction possibly through regulation of AMPK (show PRKAA1 Antibodies)-mediated cardiac autophagy.

  6. The levels of TLR4, NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies), and IkappaBalpha (show NFKBIA Antibodies) were estimated.

  7. postnatal expression of TLR2 (show TLR2 Antibodies) and TLR4 in small intestinal epithelial cells

  8. LPS was shown to inhibit osteoblast differentiation by suppressing the expression of ALP (show CCL21A Antibodies), OCN, and Runx2 (show RUNX2 Antibodies) in a TLR-4-dependent manner.

  9. In summary, our study illustrates the potential signal transduction process of PTEN (show PTEN Antibodies) while stimulated by LPS: by increasing the association of TLR4, PTEN (show PTEN Antibodies) recruits to its phosphoinositide substrate PI(3,4,5)P3 located on the cell membrane and exerts its dephosphorylated function and subsequently depresses the activity of downstream molecule Akt (show AKT1 Antibodies) and results in activation of NF-kappaB (show NFKB1 Antibodies), followed by the secretion of inflamma...

  10. Results showed the participation of neuroimmune system activation and the TLR4 signaling response since deficient mice in TLR4 (TLR4-KO) are protected against molecular and behavioral alterations of ethanol in the adolescent brain.

Cow (Bovine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. Transcription levels of TLR2 (show TLR2 Antibodies), TLR4, and CD14 (show CD14 Antibodies) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.

  2. Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.

  3. TLR2 (show TLR2 Antibodies) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  4. TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins

  5. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (show TLR2 Antibodies) and TLR4 with the formation of NETs and change in surface architecture.

  6. Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (show CCL2 Antibodies)) genes.

  7. Studied bovine TLR4 gene in mastitis resistance by association as well as expression profiling analysis in crossbred cattle.

  8. Findings indicate that intervertebral disc (IVD (show IVD Antibodies)) cells constitutively express TLR4.

  9. Data suggest that granulosa cells from dominant follicles express functional TLR2 (show TLR2 Antibodies) and TLR4; granulosa cells appear to participate in innate immunity by responding to bacterial lipopolysaccharides/lipopeptides via TLR2 (show TLR2 Antibodies) and TLR4 signaling pathways.

  10. The expressions of host TLR2 (show TLR2 Antibodies) and 4 genes were significantly higher in acidosis-resistant steers compared to those in acidosis-susceptible steers.

Rabbit Toll-Like Receptor 4 (TLR4) interaction partners

  1. The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (show NFKB1 Antibodies) (p65 (show SYT1 Antibodies)) were respectively detected.

  2. Lipopolysaccharide upregulates the expression of rabbit TLR2 (show TLR2 Antibodies) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.

  3. Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (show NFKB1 Antibodies) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (show ICAM1 Antibodies).

  4. TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage

  5. The elevated expression of TLR4 was detected after SAH (show ACSM3 Antibodies) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (show ACSM3 Antibodies).

Pig (Porcine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (show MAMLD1 Antibodies) in Meishan weaned piglets.

  2. Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (show IRF6 Antibodies) challenge.

  3. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.

  4. Data suggest TLR2 (show TLR2 Antibodies), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (show TLR2 Antibodies)/TLR4.

  5. TLR2 (show TLR2 Antibodies) is required for the suppression of TLR4 signaling activation.

  6. The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.

  7. The role of TLR2 (show TLR2 Antibodies), TLR4 and RP105 (show CD180 Antibodies)/MD1 (show LY86 Antibodies) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Antibodies), is reported.

  8. Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.

  9. Fish Oil attenuates the activation of the HPA (show HPSE Antibodies) axis induced by LPS (show IRF6 Antibodies) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.

  10. Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.

Horse (Equine) Toll-Like Receptor 4 (TLR4) interaction partners

  1. The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.

  2. A low steady expression of TLR4, MD-2 (show LY96 Antibodies) and CD14 (show CD14 Antibodies) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.

  3. In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.

  4. evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins

  5. TLR4/MD-2 (show LY96 Antibodies) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.

TLR4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TLR4

  • toll-like receptor 4 (TLR4) antibody
  • toll-like receptor 4 (Tlr4) antibody
  • ARMD10 antibody
  • CD284 antibody
  • Lps antibody
  • Ly87 antibody
  • Ran/M1 antibody
  • Rasl2-8 antibody
  • TLR-4 antibody
  • TOLL antibody

Protein level used designations for TLR4

hToll , homolog of Drosophila toll , lipopolysaccharide response , toll4 , Toll-like receptor4 protein , Toll-like receptor 4-like protein

GENE ID SPECIES
7099 Homo sapiens
21898 Mus musculus
417241 Gallus gallus
29260 Rattus norvegicus
281536 Bos taurus
100009497 Oryctolagus cuniculus
100724803 Cavia porcellus
403417 Canis lupus familiaris
399541 Sus scrofa
493698 Felis catus
100066890 Equus caballus
100860955 Capra hircus
554263 Ovis aries
100980644 Pan paniscus
100689329 Cricetulus griseus
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