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Mouse (Murine) TLR4 ELISA Kit for Sandwich ELISA - ABIN424269
Campo, Avenoso, DAscola, Prestipino, Scuruchi, Nastasi, Calatroni, Campo: Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. in Archives of biochemistry and biophysics 2012
Show all 14 Pubmed References
Human TLR4 ELISA Kit for Sandwich ELISA - ABIN414556
Kacerovsky, Andrys, Hornychova, Pliskova, Lancz, Musilova, Drahosova, Bolehovska, Tambor, Jacobsson: Amniotic fluid soluble Toll-like receptor 4 in pregnancies complicated by preterm prelabor rupture of the membranes. in The journal of maternal-fetal & neonatal medicine 2012
Show all 13 Pubmed References
Rat (Rattus) TLR4 ELISA Kit for Sandwich ELISA - ABIN416209
Kusano, Etoh, Inomata, Shiraishi, Kitano: CO(2) pneumoperitoneum increases secretory IgA levels in the gut compared with laparotomy in an experimental animal model. in Surgical endoscopy 2014
Show all 5 Pubmed References
Rat (Rattus) TLR4 ELISA Kit for Sandwich ELISA - ABIN858492
Tunc, Aydemir, Karaoglu, Cekmez, Kul, Aydinoz, Babacan, Yaman, Sarici: Toll-like receptor levels and caffeine responsiveness in rat pups during perinatal period. in Regulatory peptides 2013
Mouse (Murine) TLR4 ELISA Kit for Competition ELISA - ABIN628212
Kusunoki, Ikarashi, Hayakawa, Ishii, Kon, Ochiai, Machida, Sugiyama: Hepatic early inflammation induces downregulation of hepatic cytochrome P450 expression and metabolic activity in the dextran sulfate sodium-induced murine colitis. in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2014
An association with IL-1beta (show IL1B ELISA Kits)-511 locus and IL-1beta (show IL1B ELISA Kits)-511-TLR4-896 diplotype (CC-AA) and Type 2 Diabetes Mellitus is discussed.
TLR4 Thr399Ile polymorphism along with H. pylori infection may play critical roles in peptic ulcer development in North of Iran.
Human neutrophil elastase (show ELANE ELISA Kits) is involved in transactivation of TLR4 through activation of DUOX-2 (show DUOX2 ELISA Kits)/EGFR (show EGFR ELISA Kits) and synergistically enhances IL-12p40 production by macrophages stimulated with LPS (show IRF6 ELISA Kits).
Data show that inhibition of MAPK (show MAPK1 ELISA Kits) pathway by peroxisome proliferator-activated receptor (show PPARD ELISA Kits) gemma (PPARg (show PPARG ELISA Kits)) agonist rosiglitazone (RGZ) requires Toll-like receptor 4 (TLR4).
In cells expressing only CD36 suggests that TLR4 expression provides the cells with additional mechanisms to mediate lipid uptake. Our results indicate that TLR4 can mediate the internalization of saturated fatty acids, and of unsaturated fatty acids in presence of CD36.
An essential role of the TLR4 pathway and chronic inflammation in KSHV-induced tumorigenesis, which helps explain why HIV-infected patients, who frequently suffer from opportunistic bacterial infections and metabolic complications, frequently develop Kaposi sarcoma.
The present study reveals that TLR4 drives the production of TNFalpha (show TNF ELISA Kits) and IL-10 (show IL10 ELISA Kits) induced by L. braziliensis amastigotes and that the parasites decrease TLR4 expression on monocyte surface.
The newest research investigating Angiotensin II triggering toll like receptor 4 activation in the kidney, vasculature and central nervous system contributing to hypertension are reviewed. [review]
Neonatal cells were more potent in the activation of ERK (show EPHB2 ELISA Kits) and Akt (show AKT1 ELISA Kits) through TLR2 (show TLR2 ELISA Kits) and TLR4 co-activation.
Data suggest that endosomal localization of TICAM2 (show TICAM2 ELISA Kits) is essential for TLR4-mediated type I interferon (show IFNA ELISA Kits)-inducing signaling from endosomes; TICAM2 (show TICAM2 ELISA Kits) acts as scaffold protein (show HOMER1 ELISA Kits) and activates TICAM1 (show TICAM1 ELISA Kits); N-terminal myristoylation allows TICAM2 (show TICAM2 ELISA Kits) to anchor to endosomal membrane. (TICAM2 (show TICAM2 ELISA Kits) = toll like receptor adaptor molecule-2 (show TICAM2 ELISA Kits); TICAM1 (show TICAM1 ELISA Kits) = toll like receptor adaptor molecule-1 (show TICAM1 ELISA Kits); TLR4 = toll-like receptor 4) [REVIEW]
TLR4-NF-kappaB (show NFKB1 ELISA Kits) signal pathway is inhibited by paeonol in endotoxin-induced acute kidney injury
The present study shows that TLR-4 deficiency and genetic background influence the outcome of muscular tissue repair in aseptic lesions and yet still maintaining some level of signaling in the TLR4-mutant mice.
These data indicate that TLR4 plays a protective role in stress-induced gastric ulcer that is exerted via impacting synthesis of glucocorticoid in the adrenal gland.
TLR2 (show TLR2 ELISA Kits) and TLR4 modulate the serotonin contractile motor response in mouse colon.
TLR4 knockout mice are less responsive to sweet, umami, spicy and fat tastants. TLR4 signaling promotes ingestion of sugar and fat by a mechanism involving increased preference for such obesogenic foods.
RTFs contribute to the regulation of LPS-induced inflammatory response in RAW264.7 cells through TLR4/MD-2 (show LY96 ELISA Kits) mediated NF-kappaB (show NFKB1 ELISA Kits) and JNK (show MAPK8 ELISA Kits) pathway. It
TRAP+ osteoclast precursors, but not mature osteoclasts, can mediate bactericidal activity via phagocytosis accompanied by the production of ROS (show ROS1 ELISA Kits) and NO via TLR4-associated reprograming toward phagocytic cell type.
TLR4 signaling is critical for the development of small bowel resection-associated hepatic steatosis.
Data suggest that dietary treatment with green tea extract reduces hepatic inflammation in non-alcoholic fatty liver disease by decreasing proinflammatory signaling in liver through Tnfr1 (show TNFRSF1A ELISA Kits) (tumor necrosis factor (show TNF ELISA Kits) receptor superfamily, member 1a) and Tlr4 (toll-like receptor 4) that otherwise increases NFkappaB activation and liver injury.
TLR4-MyD88 (show MYD88 ELISA Kits) expression on B1a cells is critical for their IgM (show CD40LG ELISA Kits)-dependent atheroprotection that not only reduced lesion apoptotic cells and necrotic cores, but also decreased CD4 (show CD4 ELISA Kits) and CD8 (show CD8A ELISA Kits) T-cell infiltrates and augmented TGF-beta1 (show TGFB1 ELISA Kits) expression accompanied by reduced lesion inflammatory cytokines TNF-alpha (show TNF ELISA Kits), IL-1beta (show IL1B ELISA Kits), and IL-18 (show IL18 ELISA Kits).
STA3 (show ARHGEF3 ELISA Kits) facilitates TLR4-dependent IL-6 (show IL6 ELISA Kits) and IL-8 (show IL8 ELISA Kits) production via IL-6 (show IL6 ELISA Kits) receptor-positive feedback in endometrial cells.
Studied genetic diversity of the Toll-like receptor gene TLR4 in Czech Red and Czech Red Pied cattle. Found 8 SNPs, which were grouped into 18 haplotypes.
TLR4 polymorphisms are associated with lower reproductive Performance.
As a pilot study, the present results revealed that identified SNPs in IL8 (show IL8 ELISA Kits) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.
Transcription levels of TLR2 (show TLR2 ELISA Kits), TLR4, and CD14 (show CD14 ELISA Kits) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.
TLR2 (show TLR2 ELISA Kits) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.
TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins
positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (show TLR2 ELISA Kits) and TLR4 with the formation of NETs and change in surface architecture.
Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (show CCL2 ELISA Kits)) genes.
TLR2 (show TLR2 ELISA Kits), 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.
The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (show NFKB1 ELISA Kits) (p65 (show SYT1 ELISA Kits)) were respectively detected.
Lipopolysaccharide upregulates the expression of rabbit TLR2 (show TLR2 ELISA Kits) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.
Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (show NFKB1 ELISA Kits) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (show ICAM1 ELISA Kits).
TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage
The elevated expression of TLR4 was detected after SAH (show ACSM3 ELISA Kits) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (show ACSM3 ELISA Kits).
These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (show MAMLD1 ELISA Kits) in Meishan weaned piglets.
Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (show IRF6 ELISA Kits) challenge.
At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.
Data suggest TLR2 (show TLR2 ELISA Kits), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (show TLR2 ELISA Kits)/TLR4.
TLR2 (show TLR2 ELISA Kits) is required for the suppression of TLR4 signaling activation.
The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.
The role of TLR2 (show TLR2 ELISA Kits), TLR4 and RP105 (show CD180 ELISA Kits)/MD1 (show LY86 ELISA Kits) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 ELISA Kits), is reported.
Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.
Fish Oil attenuates the activation of the HPA (show HPSE ELISA Kits) axis induced by LPS (show IRF6 ELISA Kits) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.
Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.
The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.
A low steady expression of TLR4, MD-2 (show LY96 ELISA Kits) and CD14 (show CD14 ELISA Kits) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.
In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.
evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins
TLR4/MD-2 (show LY96 ELISA Kits) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
, homolog of Drosophila toll
, lipopolysaccharide response
, Toll-like receptor4 protein
, Toll-like receptor 4-like protein