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BDH2 expression is an independent poor prognostic factor for CN-AML (show RUNX1 ELISA Kits), with an anti-apoptotic role. Patients with high BDH2 expression have relatively shorter overall survival and a low complete response rate.
Data show that the ketone body metabolizing enzymes BDH1 (show BDH1 ELISA Kits), BDH2, OXCT1 (show OXCT1 ELISA Kits) and ACAT1 (show ACAT1 ELISA Kits) were expressed at the mRNA and protein level in all glioma cell lines.
DHRS6 is an orphan short chain dehydrogenase/ reductase (show SDR9C7 ELISA Kits) enzyme
3-hydroxybutyrate dehydrogenase (show BDH1 ELISA Kits)-2 catalyzes a rate-limiting step in the biogenesis of the mammalian siderophore.
these findings demonstrate a key role for BDH2 in erythropoiesis.
The Bdh2 role in erythrocyte maturation and mitophagy
Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity).
dehydrogenase/reductase (SDR family) member 6
, 3-hydroxybutyrate dehydrogenase, type 2
, 3-hydroxybutyrate dehydrogenase type 2
, 3-hydroxybutyrate dehydrogenase type-2
, R-beta-hydroxybutyrate dehydrogenase
, dehydrogenase/reductase SDR family member 6
, oxidoreductase UCPA
, short chain dehydrogenase/reductase family 15C, member 1