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In our analyses of the DYX2 (show KIAA0319 Proteins) locus, we observed associations of KIAA0319 (show KIAA0319 Proteins), ACOT13 (show ACOT13 Proteins), and FAM65B with developing cortical thickness and/or functional anisotropy.
These data together elucidate a mechanism for RHOA (show RHOA Proteins) and pMLC polarization in stimulated neutrophils through direct inhibition of RHOA (show RHOA Proteins) by FAM65B at the leading edge.
Fam65b expression is necessary for the complex to form.
show that wild-type Fam65b is expressed during embryonic and postnatal development stages in murine cochlea, and that the protein localizes to the plasma membranes of the stereocilia of inner and outer hair cells of the inner ear
PC3 (show PCSK1 Proteins) tumors are sustained by a small number of tumor-initiating cells with stem-like characteristics, including strong self-renewal and pro-angiogenic capability and marked by the expression pattern FAM65Bhigh/MFI2low/LEF1low.
C6ORF32 is a novel protein likely to play multiple functions, including promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation
The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Two alternatively spliced transcript variants have been found for this gene.
family with sequence similarity 65, member B
, myogenesis-related and NCAM-associated protein homolog
, protein FAM65B
, likely orthologue of H. sapiens chromosome 6 open reading frame 32 (C6orf32)
, myogenesis-related and NCAM-associated protein