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Human Polyclonal FTH1 Primary Antibody for WB - ABIN515829
Kim, Moore, Fussenegger: Genetically programmed superparamagnetic behavior of mammalian cells. in Journal of biotechnology 2012
Human Polyclonal FTH1 Primary Antibody for IF (p), IHC (p) - ABIN759641
Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis. in Toxicology and applied pharmacology 2016
Cow (Bovine) Polyclonal FTH1 Primary Antibody for IHC, WB - ABIN2785803
Sammarco, Ditch, Banerjee, Grabczyk: Ferritin L and H subunits are differentially regulated on a post-transcriptional level. in The Journal of biological chemistry 2008
Show all 2 Pubmed References
Fe mediated decrease of lateral root length and density is enhanced in fer1-3-4 triple mutant plants.
phosphate starvation response of AtFer1 is not linked to the iron status of plants and is specifically initiated by phosphate deficiency
Data indicate that steady-state mRNA abundance for three representative Fe homeostasis genes, IRT1 (show PARP3 Antibodies), bHLH39, and FER1, oscillated in light/dark (LD) cycles or warm/cold environmental cycles.
Data show that a leaf glutathione concentration threshold between 10 and 50 nmol GSHg(-1) FW is required for full induction of AtFer1 gene expression in response to iron.
new regulatory pathway involved in plant response to oxidative stress was revealed using the iron-induced Arabidopsis ferritin (show FTL Antibodies) AtFER1 as a model
Ferritin (show FTL Antibodies) accumulation during infection of Arabidopsis by E. chrysanthemi is a basal defense mechanism which is mainly activated by bacterial siderophores.
The X-ray crystal structure of the apoferritin-SDS (show SDS Antibodies) complex was determined at a resolution of 1.9 A and revealed that the SDS (show SDS Antibodies) binds in an internal cavity that has previously been shown to recognize various general anesthetics. [apoferritin]
Transmission electron microscopy shows a clear selectivity of alkylated ferritin (show FTL Antibodies) adsorption onto the PCL (show PKD2L1 Antibodies) phase while wild ferritin (show FTL Antibodies) predominantly adsorbs onto the PDTD phase.
the absence of Mitochondrial ferritin (show FTMT Antibodies), which is highly expressed in the heart, increases the sensitivity of mitochondria to cardiac injury via oxidative stress.
As previously reported, homozygous loss of the Fth allele on a wild-type Ftl (show FTL Antibodies) background was embryonic lethal. expression of the H subunit can rescue the loss of the L subunit and that H ferritin homopolymers have the capacity to sequester iron in vivo
provide a new mechanism for selective autophagy of ferritin (show FTL Antibodies) and reveal a previously unappreciated role for autophagy and NCOA4 (show NCOA4 Antibodies) in the control of iron homeostasis in vivo
Our data show that ferritin H (show FTMT Antibodies) is required for B and T cell survival by actively reducing the labile iron pool.
Ferritin H (show FTMT Antibodies) deficiency in most cells of the forebrain including cells of the choroid plexus caused accumulation of cerebrospinal fluid in the lateral ventricles and the subarachnoid space
Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2 (show TLR2 Antibodies).
3-Hydroxybutyrate dehydrogenase (show BDH1 Antibodies)-2 and ferritin-H (show FTMT Antibodies) synergistically regulate intracellular iron.
Fth plays a critical protective role during acute kidney injury.
FtH provides metabolic adaptation to tissue Fe overload, conferring tolerance to malaria
The delivery of iron to oligodendrocytes via H-ferritin is a biologically relevant delivery system, given that ferritin (show FTL Antibodies)--not transferrin (show Tf Antibodies)--receptors can be demonstrated on oligodendrocytes in vivo.
Low levels of FTH-positive tumor cells and microglia/macrophages were associated with poor survival in anaplastic astrocytomas, while high amounts of FTL (show FTL Antibodies)-positive microglia/macrophages had a negative prognostic value
fumarate increases ferritin (show FTL Antibodies) gene transcription by activating the NRF2 (show GABPA Antibodies) (nuclear factor [erythroid-derived 2]-like 2) transcription factor.
there is no significant relationship between serum ferritin (show FTL Antibodies) concentrations and depressive symptoms among Chinese adults.
Data suggest that, in homopolymeric H-subunit ferritin (show FTL Antibodies) (HuHF), iron oxidation proceeds with a 2:1 Fe(II):O(2) stoichiometry at iron level of 2 Fe(II) atoms/H-subunit with generation of H2O2; L-subunit-rich heteropolymeric ferritin (show FTL Antibodies) also facilitates iron oxidation at the ferroxidase (show CP Antibodies) center and additionally promotes oxidation at the mineral surface once iron-binding capacity has been exceeded.
Elevated serum ferritin (show FTL Antibodies) levels are associated with hematologic malignancies.
Ferritin light chain (show FTL Antibodies) and ferritin heavy chain are required for the neural differentiation of bone marrow-derived mesenchymal stem cells under extremely low-frequency electromagnetic field.
Human FTH1 is a general pro-survival sequence.
H-ferritin tissue expression and the number of CD68 (show CD68 Antibodies)+/H-ferritin+ cells were increased in the lymph nodes of adult-onset Still's disease patients, and these results correlated significantly with disease severity
Studies indicate that the the best characterized cytosolic ferritins in mammals are encoded by two genes, FTH and FTL (show FTL Antibodies), with four exons and similar structures.
high cytoplasmic FTH1 was associated with favorable prognosis whereas nuclear FTH1 staining was associated with adverse prognosis in triple negative breast cancer
ferritin heavy chain up-regulation may be mediated by activation of NF-kappaB (show NFKB1 Antibodies) and that in turn this may be related to the resistance of bovine papillomavirus type-2 (BPV-2) infected urothelial cells to apoptosis.
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
ferritin heavy chain
, ferritin, heavy polypeptide 1
, ferritin H subunit B
, ferritin heavy chain 1
, ferritin heavy chain B
, ferritin, heavy polypeptide 1 b
, ferritin H chain
, ferritin H subunit
, Ferritin H subunit
, cell proliferation-inducing gene 15 protein
, placenta immunoregulatory factor
, proliferation-inducing protein 15
, ferritin heavy-chain
, Ferritin subunit H
, ferritin heavy polypeptide 1
, ferritin, heavy polypeptide-like 17 like 5