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Mouse (Murine) TFRC ELISA Kit for Sandwich ELISA - ABIN424656
Cheng, Zhou, Li, Liu, Wang, Zhang: The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice. in Food & function 2016
Human TFRC ELISA Kit for Sandwich ELISA - ABIN415211
Xia, Zhang, Wang, Sun, Wu: Survey of anaemia and Helicobacter pylori infection in adolescent girls in Suihua, China and enhancement of iron intervention effects by H. pylori eradication. in The British journal of nutrition 2012
Tfrc deletion dramatically suppressed both transforming growth factor-beta (TGF-beta) and bone morphogenetic protein (BMP) signaling in cranial neural crest cell-derived mandibular tissues.
decreasing TfR1 expression during beta-thalassemic erythropoiesis, either directly via induced haploinsufficiency or via exogenous apotransferrin, decreases ineffective erythropoiesis and provides an endogenous mechanism to upregulate hepcidin (show HAMP ELISA Kits), leading to sustained iron-restricted erythropoiesis and preventing systemic iron overload in beta-thalassemic mice
the value of transferrin receptors (TfRs)/cell reveals a 100-fold increase in the number of TfRs per bEnd3 cells compared to human umbilical vein cells.
our study reveals that TFR functions as a novel regulator to control AMPA (show GRIA3 ELISA Kits) trafficking efficiency and synaptic plasticity
We found that iron assimilation via Tfr1 was critical for skeletal muscle metabolism, and that iron deficiency in muscle led to dramatic changes, not only in muscle, but also in adipose tissue and liver.
Mice lacking Tfr1 in the heart died in the second week of life and had cardiomegaly, poor cardiac function, failure of mitochondrial respiration, and ineffective mitophagy.
Transferrin Receptor 1 (show TFR ELISA Kits) Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.
Erythrocytic iron deficiency enhances susceptibility to Plasmodium chabaudi infection in mice carrying a missense mutation in tfr1.
Tfr1 has a role in homeostatic maintenance of the intestinal epithelium, acting through a role that is independent of its iron-uptake function
Analysis by qPCR showed changes in mRNA levels of iron-responsive genes, indicating moderately increased iron in the RPE of 10-month HID mice.
TfR1 was highly expressed in glioblastomas and associated with shorter survival in the whole cohort, but not in the individual malignancy grades
Expression of Hepcidin (show HAMP ELISA Kits) and Ferroportin (show SLC40A1 ELISA Kits) in the Placenta, and Ferritin (show FTL ELISA Kits) and Transferrin Receptor 1 (show TFR ELISA Kits) Levels in Maternal and Umbilical Cord Blood in Pregnant Women with and without Gestational Diabetes
Transferrin (show Tf ELISA Kits) facilitates the formation of DNA double-strand breaks (DNA-DSBs) via transferrin receptor TfR1 but not TfR2 (show TFR2 ELISA Kits).
Human melanoma cells are able to up-regulate TFRC expression using hyaluronan/CD44 (show CD44 ELISA Kits) signaling.
high expression of transferrin receptor-1 (show TFR ELISA Kits) resulting in iron uptake contributes to increase in the labile iron pool which plays roles in cholangiocarcinoma progression with aggressive clinical outcomes.
EGFR (show EGFR ELISA Kits) regulates iron homeostasis to promote non-small cell lung cancer growth through redistribution of transferrin receptor 1 (show TFR ELISA Kits).
TFR1 is overexpressed in adult T-cell leukemia/lymphoma caells .
NSF (show NSF ELISA Kits) deficiency in HeLa cells barely affected cell viability, anterograde trafficking of vesicular stomatitis virus glycoprotein G and transferrin (show Tf ELISA Kits) endocytosis.
inhibition of c-Abl (show ABL1 ELISA Kits) minimizes receptor recycling pathways and results in chaperone-dependent trafficking of the TfR1 to the lysosome for degradation.
alpha6(high)/CD71(low) cells give rise to a thicker pluristratified epithelium with lower seeding density and display a low Ki67 (show MKI67 ELISA Kits) positive cells number, showing that they have reached the balance between proliferation and differentiation.
These data indicate that TfR1 expression in serum exosomes may provide a marker for regeneration in anaemic horses.
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
transferrin receptor protein 1
, transferrin receptor (p90, CD71)
, mammary tumor virus receptor 1