Browse our Transferrin Receptor 2 (TFR2) ELISA Kits

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Transferrin Receptor 2 ELISA Kits (TFR2)
On are 45 Transferrin Receptor 2 (TFR2) ELISA Kits from 9 different suppliers available. Additionally we are shipping Transferrin Receptor 2 Antibodies (66) and Transferrin Receptor 2 Proteins (17) and many more products for this protein. A total of 133 Transferrin Receptor 2 products are currently listed.
HFE3, TFR2, TFRC2, Trfr2, zgc:123043

Top referenced Transferrin Receptor 2 ELISA Kits

  1. Mouse (Murine) Transferrin Receptor 2 ELISA Kit for Sandwich ELISA - ABIN415732 : Cheng, Zhou, Li, Liu, Wang, Zhang: The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice. in Food & function 2016 (PubMed)

More ELISA Kits for Transferrin Receptor 2 Interaction Partners

Mouse (Murine) Transferrin Receptor 2 (TFR2) interaction partners

  1. erythroid Tfr2 is essential for an appropriate erythropoietic response in iron-deficient anemia

  2. These studies further elucidate the role of TFR2 in the regulation of iron homeostasis and its role in regulation of ferroportin (show SLC40A1 ELISA Kits) and thus macrophage iron homeostasis

  3. Tfr2 is a novel target gene for HNF4alpha (show HNF4A ELISA Kits), and hepatic HNF4alpha (show HNF4A ELISA Kits) plays a critical role in iron homeostasis.

  4. There is an essential role for TFR2 in erythropoiesis that may provide new targets for the treatment of anaemia.

  5. We suggest that Tfr2 is a component of a novel iron-sensing mechanism that adjusts erythrocyte production according to iron availability, likely by modulating the erythroblast Epo (show EPO ELISA Kits) sensitivity.

  6. We propose that TFR2 is a limiting factor for erythropoiesis, particularly in conditions of iron restriction.

  7. These results support in vivo studies which suggest that Hfe (show HFE ELISA Kits) and Tfr2 can independently regulate hepcidin (show HAMP ELISA Kits).

  8. we used microarray and real-time reverse transcription polymerase chain reaction to assess brain transcriptome profiles of transferrin receptor 2 mutant mice a model of a rare type of hereditary hemochromatosis (show HFE ELISA Kits)

  9. Double mutant mice lacking functional Hfe (show HFE ELISA Kits) or Tfr2 and Tmprss6 (show TMPRSS6 ELISA Kits) exhibited a severe iron deficiency microcytic anemia phenotype mimicking the phenotype of single mutant mice lacking functional Tmprss6 (show TMPRSS6 ELISA Kits) demonstrating that Hfe (show HFE ELISA Kits) and Tfr2 are not substrates for Tmprss6 (show TMPRSS6 ELISA Kits).

  10. Disruption of both Hfe (show HFE ELISA Kits) and Tfr2 caused more severe hepatic iron overload with more advanced lipid peroxidation, inflammation, and portal fibrosis than was observed with the disruption of either gene alone.

Human Transferrin Receptor 2 (TFR2) interaction partners

  1. In line with a status of iron deficiency, gene expression studies suggested decreased expression of transferrin (show Tf ELISA Kits) and transferrin receptor 2 in non-alcoholic steatohepatitis livers

  2. Our results indicate that membrane transferrin receptor-2, a sensor of circulating iron, is released from the cell membrane in iron deficiency.

  3. results suggest that down-regulation of CD81 (show CD81 ELISA Kits) by GRAIL (show RNF128 ELISA Kits) targets TfR2 for degradation

  4. Polymorphisms of the TRF2 (show TERF2 ELISA Kits) gene may be associated with age-related macular degeneration occurrence, either directly or by modulation of risk factors.

  5. The variants of rs2075674 and rs7385804 in TFR2 gene were not associated with coronary heart disease risk in a Chinese Han population.

  6. Present findings support the hypothesis of a main role of the TFR2 gene in HH pathogenesis in those regions, such as Central-Southern Italy, where the p.C282Y frequency is low.

  7. Authors investigated the expression of TfR1 (show TFRC ELISA Kits) and TfR2 in human HCC (show FAM126A ELISA Kits) tissues by immunohistochemistry, the first report demonstrating TfR2 expression immunohistochemically in human HCC (show FAM126A ELISA Kits).

  8. N-linked glycosylation is dispensable for the cell surface expression and holo-Tf binding, but it is required for efficient intersubunit disulfide bond formation and holo-Tf-induced stabilization of TfR2.

  9. Studies indicate that several genes have been linked to iron homeostasis, including transferrin (show Tf ELISA Kits) (TF), iron regulatory protein 1 (ACO1 (show ACO1 ELISA Kits)) and transferrin receptor 2 (TFR2).

  10. The hemochromatosis (show HFE ELISA Kits) proteins HFE (show HFE ELISA Kits), TfR2, and HJV (show HFE2 ELISA Kits) form a membrane-associated protein (show PDZK1IP1 ELISA Kits) complex for hepcidin (show HAMP ELISA Kits) regulation.

Cow (Bovine) Transferrin Receptor 2 (TFR2) interaction partners

  1. One novel SNPs was identified in TFR2 which tended to be associated (P < 0.013) with skeletal muscle iron content.

Zebrafish Transferrin Receptor 2 (TFR2) interaction partners

  1. TfR2 is coexpressed with transferrin-a (show Tf ELISA Kits) in the liver of the zebrafish embryo. Knockdown of TfR2 fails to produce anemia or a morphologic defect.

Transferrin Receptor 2 (TFR2) Antigen Profile

Antigen Summary

This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with Transferrin Receptor 2 (TFR2)

  • transferrin receptor 2 (TFR2) Elisa Kit
  • transferrin receptor 2 (Tfr2) Elisa Kit
  • transferrin receptor 2 (tfr2) Elisa Kit
  • HFE3 Elisa Kit
  • TFR2 Elisa Kit
  • TFRC2 Elisa Kit
  • Trfr2 Elisa Kit
  • zgc:123043 Elisa Kit

Protein level used designations for TFR2

transferrin receptor 2 , transferrin receptor protein 2-like , transferrin receptor protein 2

463605 Pan troglodytes
719240 Macaca mulatta
100395993 Callithrix jacchus
100457089 Pongo abelii
100466518 Ailuropoda melanoleuca
50765 Mus musculus
7036 Homo sapiens
288562 Rattus norvegicus
100712922 Cavia porcellus
100517580 Sus scrofa
489834 Canis lupus familiaris
617916 Bos taurus
100357314 Oryctolagus cuniculus
494476 Danio rerio
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