Browse our anti-Cofilin1/2 (CFL1/2) Antibodies

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anti-Cofilin1/2 Antibodies (CFL1/2)
On are 13 Cofilin1/2 (CFL1/2) Antibodies from 5 different suppliers available. A total of 13 Cofilin1/2 products are currently listed.
list all antibodies Gene Name GeneID UniProt
CFL1/2 1072 P23528

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Top referenced anti-Cofilin1/2 Antibodies

  1. Human Polyclonal CFL1/2 Primary Antibody for IF, IHC - ABIN363074 : Chen, Cizeau, Vande Velde, Park, Bozek, Bolton, Shi, Dubik, Greenberg: Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for 363074

  2. Human Polyclonal CFL1/2 Primary Antibody for IHC - ABIN362442 : Arber, Barbayannis, Hanser, Schneider, Stanyon, Bernard, Caroni: Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. in Nature 1998 (PubMed)
    Show all 4 references for 362442

More Antibodies against Cofilin1/2 Interaction Partners

Human Cofilin1/2 (CFL1/2) interaction partners

  1. In advance urothelial cancer, overexpression of nuclear cofilin (show CFL1 Antibodies) correlates with bladder cancer progression.

  2. Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics.

  3. STMN1 (show STMN1 Antibodies),COF1 (show CFL1 Antibodies) and PAIRBP1 (show SERBP1 Antibodies) thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 (show THBS2 Antibodies) and POSTN (show POSTN Antibodies) were connected to low grade tumors with better prognosis

  4. We observed marked increases in LIM kinase 2 (LIMK2 (show LIMK2 Antibodies)) and cofilin 1 (CFL1 (show CFL1 Antibodies)) gene expressions in metabolic syndrome patients.

  5. Therefore, miR (show MLXIP Antibodies)-138/LIMK1 (show LIMK1 Antibodies)/cofilin (show CFL1 Antibodies) may be considered a potential therapeutic target for the treatment of non-small cell lung cancer

  6. These findings indicate that inhibition of the Rac1WAVE2Arp2/3 signaling pathway may promote radiosensitivity, which may partially result from the downregulation of CFL1 (show VPS72 Antibodies) in U251 human glioma cells.

  7. The present findings demonstrated that the anticancer effect of docetaxel induces the apoptosis of prostate cancer via the suppression of the cofilin1 and paxillin (show PXN Antibodies) signaling pathways, which will assist in setting a stage for the clinical treatment of prostate cancer.

  8. VEGFA (show VEGFA Antibodies) induced phosphorylation of Pak1 (show PAK1 Antibodies) and its effector cofilin (show CFL1 Antibodies) in a manner that was dependent on time as well as p38MAPKbeta.

  9. CFL1 (show VPS72 Antibodies) itself does not translocate actin into the cell nucleus but this transport requires the functional expression of IPO9 (show IPO9 Antibodies).

  10. Abnormal CFL1 (show VPS72 Antibodies) expression may affect vulvar carcinogenesis and subsequent progression.

Cofilin1/2 (CFL1/2) Antigen Profile

Antigen Summary

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Alternative names and synonyms associated with Cofilin1/2 (CFL1/2)

  • cofilin 1 (non-muscle) (CFL1) antibody
  • CFL antibody

Protein level used designations for anti-Cofilin1/2 (CFL1/2) Antibodies

18 kDa phosphoprotein , cofilin, non-muscle isoform , cofilin-1 , p18

1072 Homo sapiens
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