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Browse our anti-HAND1 (HAND1) Antibodies

Full name:
anti-Heart and Neural Crest Derivatives Expressed 1 Antibodies (HAND1)
On www.antibodies-online.com are 84 Heart and Neural Crest Derivatives Expressed 1 (HAND1) Antibodies from 18 different suppliers available. Additionally we are shipping HAND1 Proteins (13) and HAND1 Kits (6) and many more products for this protein. A total of 108 HAND1 products are currently listed.
Synonyms:
bHLHa27, eHAND, Ehand1, hand-1, Hand1, hand1-A, HXT, Th1, Thing1
list all antibodies Gene Name GeneID UniProt
HAND1 9421 O96004
HAND1 59112 P97832
HAND1 15110 Q64279

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anti-Human HAND1 Antibodies:

anti-Rat (Rattus) HAND1 Antibodies:

anti-Mouse (Murine) HAND1 Antibodies:

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Top referenced anti-HAND1 Antibodies

  1. Human Polyclonal HAND1 Primary Antibody for WB - ABIN658328 : Reamon-Buettner, Ciribilli, Traverso, Kuhls, Inga, Borlak: A functional genetic study identifies HAND1 mutations in septation defects of the human heart. in Human molecular genetics 2009 (PubMed)
    Show all 4 references for ABIN658328

  2. Human Monoclonal HAND1 Primary Antibody for ELISA, WB - ABIN2869339 : Dai, Cserjesi: The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN2869339

  3. Human Monoclonal HAND1 Primary Antibody for ELISA, WB - ABIN969184 : Lexer, Welch, Durphy, Rieseberg: Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species. in Molecular ecology 2003 (PubMed)
    Show all 2 references for ABIN969184

  4. Human Monoclonal HAND1 Primary Antibody for ELISA, WB - ABIN4316554 : Lu, Du, Shan, Wang, Ma, Dong: Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture. in Biochemical and biophysical research communications 2016 (PubMed)

  5. Human Polyclonal HAND1 Primary Antibody for IHC, ELISA - ABIN1532673 : Knöfler, Meinhardt, Vasicek, Husslein, Egarter: Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart. in Gene 1999 (PubMed)

  6. Human Polyclonal HAND1 Primary Antibody for ICC, IF - ABIN4316555 : Zhang, Chen, Ye, Wang, Wang, Yuan, Lin, Wu, Zhang, Lin: Wnt signaling promotes hindgut fate commitment through regulating multi-lineage genes during hESC differentiation. in Cellular signalling 2016 (PubMed)

More Antibodies against HAND1 Interaction Partners

Human Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Strikingly, human pluripotent stem cell antibody array showed that Hand1 overexpression resulted in substantial decrease in pluripotency markers (Nanog (show NANOG Antibodies), Oct3/4 (show POU5F1 Antibodies), Otx2 (show OTX2 Antibodies), Flk1 (show KDR Antibodies)) suggesting that Hand1 expression may be essential to attenuate the EMT (show ITK Antibodies) and our findings underscore a novel role for Hand1 in medulloblastoma metastasis.

  2. association of HAND1 loss-of-function mutation with increased susceptibility to Tetralogy of Fallot

  3. These findings expand the phenotypic spectrum linked to HAND1 mutations, suggesting potential implications for the development of novelo prophylactic and therapeutic strategies for DORV.

  4. HAND1 loss-of-function mutation is associated with familial dilated cardiomyopathy.

  5. Combined expression of NKX2-5 (show NKX2-5 Antibodies), HAND1, and NOTCH1 (show NOTCH1 Antibodies) coordinately contribute to cardiac malformations in Hhypoplastic left heart syndrome.

  6. These data show that miR (show MLXIP Antibodies)-363 negatively regulates the expression of HAND1

  7. Nuclear translocation of Hand-1 acts as a molecular switch to regulate vascular radiosensitivity in medulloblastoma tumors.

  8. DNA methylation (show HELLS Antibodies) status of NKX2-5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies) and HAND1 in patients with tetralogy of fallot

  9. Increased methylation levels of HAND1 is associated with highly active Helicobacter pylori-related gastritis.

  10. This is the first report of mutations in the HAND1 gene in Chinese patients with VSD and provides new insight into the etiology of VSD

Xenopus laevis Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. increased vascular endothelial growth factor(170) levels disturb Hand-1 expression in the region required for normal heart morphogenesis

Mouse (Murine) Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Data suggest the protection role of haploinsufficiency of heart and neural crest derivatives expressed transcript 1 protein (Hand1) after acute myocardial infarction (AMI (show CFD Antibodies)).

  2. Hand1 is involved in proper osteogenesis of the bone collar via its control of Ihh (show IHH Antibodies). Hand1 overexpression in the osteochondral progenitors caused defective prenatal diaphysis ossification. Hand1 inhibited Runx2 (show RUNX2 Antibodies) transactivation of the Ihh (show IHH Antibodies) proximal promoter.

  3. Re-expression of HAND1 in colon cancer cells induces terminal differentiation.

  4. Hand1 phosphoregulation in the distal arch neural crest has a critical role in craniofacial morphogenesis

  5. Suggest that prenatal alcohol exposure causes the over-expression of DHAND (show HAND2 Antibodies) and EHAND by increasing H3K14ac in the fetal heart.

  6. Hand1 is part of a novel regulatory pathway linking cardiac oxygen levels with oxygen consumption.

  7. that Hand1 homodimer plays a dominant role during development and its expression dosage is critical for survival, whereas Hand1 heterodimers can be either dispensable or play a regulatory role to modulate the activity of Hand1 homodimer in vivo.

  8. Data suggest that stress-induced MAPK8/9 and PRKAA1/2 regulate transcription factors Eomes/HAND1 and ID2, respectively. Together this network mediates induction of CSH1 by stress.

  9. Hand1-mediated activation of Tbeta4 is essential for yolk sac (show ADCY10 Antibodies) vasculogenesis and embryonic survival, and administration of synthetic TB4 partially rescues yolk sac (show ADCY10 Antibodies) capillary plexus formation in Hand1-null embryos.

  10. Data define a critical threshold of Hand1 expression that is necessary for embryonic survival.

HAND1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Alternative names and synonyms associated with HAND1

  • heart and neural crest derivatives expressed 1 (HAND1) antibody
  • heart and neural crest derivatives expressed 1 (hand1) antibody
  • eHAND basic helix-loop-helix transcription factor (EHAND) antibody
  • heart and neural crest derivatives expressed 1 (Hand1) antibody
  • heart and neural crest derivatives expressed transcript 1 (Hand1) antibody
  • bHLHa27 antibody
  • eHAND antibody
  • Ehand1 antibody
  • hand-1 antibody
  • Hand1 antibody
  • hand1-A antibody
  • HXT antibody
  • Th1 antibody
  • Thing1 antibody

Protein level used designations for HAND1

heart- and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed 1 , basic helix-loop-helix transcription factor HAND1 , eHAND basic helix-loop-helix transcription factor , Heart- and neural crest derivatives-expressed protein 1 , class A basic helix-loop-helix protein 27 , extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed transcript 1 , heart and neural crest derivatives-expressed protein 1 , eHAND , helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast , thing-1

GENE ID SPECIES
489164 Canis lupus familiaris
541594 Sus scrofa
462209 Pan troglodytes
549497 Xenopus (Silurana) tropicalis
714450 Macaca mulatta
100009575 Oryctolagus cuniculus
9421 Homo sapiens
59112 Rattus norvegicus
517952 Bos taurus
395812 Gallus gallus
443353 Ovis aries
373663 Xenopus laevis
15110 Mus musculus
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