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Integrin beta 1 Binding Protein 1 Proteins (ITGB1BP1)
On www.antibodies-online.com are 7 Integrin beta 1 Binding Protein 1 (ITGB1BP1) Proteins from 4 different suppliers available. Additionally we are shipping Integrin beta 1 Binding Protein 1 Antibodies (56) and Integrin beta 1 Binding Protein 1 Kits (1) and many more products for this protein. A total of 67 Integrin beta 1 Binding Protein 1 products are currently listed.
Synonyms:
AI449260, AU019480, ICAP-1A, ICAP-1alpha, ICAP-1B, Icap1, ICAP1A, ICAP1B, si:dkey-27p7.1, zgc:123198
list all proteins Gene Name GeneID UniProt
Rat ITGB1BP1 ITGB1BP1 298914  
ITGB1BP1 9270 O14713
ITGB1BP1 16413 O35671

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Integrin beta 1 Binding Protein 1 Proteins (ITGB1BP1) by Origin

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More Proteins for Integrin beta 1 Binding Protein 1 Interaction Partners

Human Integrin beta 1 Binding Protein 1 (ITGB1BP1) interaction partners

  1. ICAP-1 monoubiquitylation helps in switching from ROCK2 (show ROCK2 Proteins)-mediated to MRCKalpha-mediated cell contractility.

  2. nuclear-cytoplasmic shuttling of ICAP1 influences both integrin activation and KRIT1 (show KRIT1 Proteins) localization, presumably impacting nuclear functions of KRIT1 (show KRIT1 Proteins).

  3. The cocrystal structure of ICAP1 in complex with krev (show RAP1B Proteins) interaction trapped protein (KRIT)1 (show KRIT1 Proteins) is characterized here.

  4. The structural basis for KRIT1 (show KRIT1 Proteins) antagonized ICAP1-modulated integrin-beta1 activation.

  5. Annexin A1 (show ANXA1 Proteins) is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.

  6. Identify ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis.

  7. Site-directed mutagenesis showed that Leu(135), Ile(138), and Ile(139) of Icap1 alpha, and Leu(82) and Tyr (show TYR Proteins)(144), are required for the Icap1 alpha-beta(1) integrin interaction

  8. Integrin-binding protein also interacts with Krit 1 (show KRIT1 Proteins) protein, cause of CCM1 (show KRIT1 Proteins). (ICAP-1, integrin cytoplasmic domain-associated protein 1)

  9. beta(1) integrin viability signal in collagen matrices is transduced by focal adhesion kinase

  10. ICAP-1 shuttles between the nucleus and cytoplasm in a beta1 integrin-dependent manner

Mouse (Murine) Integrin beta 1 Binding Protein 1 (ITGB1BP1) interaction partners

  1. ICAP-1 monoubiquitylation helps in switching from ROCK2 (show ROCK2 Proteins)-mediated to MRCKalpha-mediated cell contractility.

  2. The CCM1 (show KRIT1 Proteins) loss resulted in ICAP-1 destabilization, which increased beta1 integrin activation and led to increased RhoA (show RHOA Proteins)-dependent contractility.

  3. Data show that phosphorylation of ICAP-1alpha by CaMKII (show CAMK2G Proteins) controls beta1 integrin activation and cell adhesion.

  4. The ICAP-1 works in concert with kindlin-2 (show FERMT2 Proteins) to control the dynamics of beta1 integrin-containing fibrillar adhesions and, thereby, regulates fibronectin (show FN1 Proteins) deposition and osteoblast mineralization.

  5. Live cell imaging, which was performed in both Icap-1-deficient mouse embryonic fibroblasts and cells expressing active beta(1) integrin, shows that the integrin high affinity state favored by talin is antagonistically controlled by ICAP-1.

  6. ICAP-1 regulates beta1 integrin-dependent cell migration by affecting the pattern of focal adhesion formation.

  7. Identify ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis.

  8. Integrin cytoplasmic domain-associated protein-1 (ICAP-1) binds ROCK to beta1 integrin at the cell membrane (ICAP-1)

  9. ICAP-1 promotes differentiation of osteoprogenitors by supporting their condensation through modulating the integrin high affinity state.

Integrin beta 1 Binding Protein 1 (ITGB1BP1) Protein Profile

Protein Summary

The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.

Alternative names and synonyms associated with Integrin beta 1 Binding Protein 1 (ITGB1BP1)

  • integrin beta 1 binding protein 1 (Itgb1bp1)
  • integrin beta 1 binding protein 1 (itgb1bp1)
  • integrin beta 1 binding protein 1 (ITGB1BP1)
  • AI449260 protein
  • AU019480 protein
  • ICAP-1A protein
  • ICAP-1alpha protein
  • ICAP-1B protein
  • Icap1 protein
  • ICAP1A protein
  • ICAP1B protein
  • si:dkey-27p7.1 protein
  • zgc:123198 protein

Protein level used designations for ITGB1BP1

integrin beta-1-binding protein 1 , ICAP-1 , bodenin , integrin cytoplasmic domain-associated protein 1 , integrin cytoplasmic domain-associated protein 1-alpha , integrin cytoplasmic domain-associated protein 1-beta

GENE ID SPECIES
298914 Rattus norvegicus
641420 Danio rerio
9270 Homo sapiens
16413 Mus musculus
513531 Bos taurus
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