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Browse our Lipoic Acid Synthetase (LIAS) ELISA Kits

Full name:
Lipoic Acid Synthetase ELISA Kits (LIAS)
On www.antibodies-online.com are 4 Lipoic Acid Synthetase (LIAS) ELISA Kits from 2 different suppliers available. Additionally we are shipping Lipoic Acid Synthetase Antibodies (26) and Lipoic Acid Synthetase Proteins (14) and many more products for this protein. A total of 47 Lipoic Acid Synthetase products are currently listed.
Synonyms:
7a5ex, 2900022L22Rik, 4933425M12Rik, C77512, LAS, Lip-syn, LIP1, LS, mLip1, PDHLD, zgc:66080

Lipoic Acid Synthetase (LIAS) ELISA Kits by Reactivity

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More ELISA Kits for Lipoic Acid Synthetase Interaction Partners

Human Lipoic Acid Synthetase (LIAS) interaction partners

  1. oxoglutarate dehydrogenase (OGDH (show alphaKGDHC ELISA Kits)) and lipoic acid synthase (LIAS), which when mutated stabilize HIF1alpha (show HIF1A ELISA Kits) in a non-hydroxylated form.

  2. heterozygous mutations (c.738-2A>G and c.929T>C (p.Met310Thr)) in LIAS.

  3. Patients with LIAS nonketotic hyperglycinemia varied in disease severity and cortical involvement.

  4. We identified the homozygous mutation c.746G>A (p.Arg249His) in LIAS in an individual with neonatal-onset epilepsy, muscular hypotonia, lactic acidosis, and elevated glycine concentration in plasma and urine

  5. Lipoic acid synthetase deficiency results in an overall disturbance in the antioxidant defense network, leading to increased inflammation, insulin (show INS ELISA Kits) resistance, and mitochondrial dysfunction.

Mouse (Murine) Lipoic Acid Synthetase (LIAS) interaction partners

  1. Decreased endogenous lipoic acid gene expression plays a role in development of diabetic atherosclerosis in ApoE (show APOE ELISA Kits) deficient mice.

  2. Lias deficiency enhances atherosclerosis in male mice, at least in part due to reduced antioxidant capacity

  3. Development of homozygous embryos lacking Lias is retarded.

  4. Enhanced neutrophil sequestration in the livers of Lias+/- mice was associated with increased hepatocyte injury and increased gene expression of growth-related oncogene (show RAB1A ELISA Kits), E-selectin (show SELE ELISA Kits), and VCAM-1 (show VCAM1 ELISA Kits) in the liver and/or lung.

Lipoic Acid Synthetase (LIAS) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with Lipoic Acid Synthetase (LIAS)

  • lipoic acid synthetase (AaeL_AAEL009368) Elisa Kit
  • lipoic acid synthetase (THAPSDRAFT_31845) Elisa Kit
  • lipoic acid synthetase (THAPSDRAFT_31673) Elisa Kit
  • lipoic acid synthetase (UREG_00501) Elisa Kit
  • lipoic acid synthetase (LOAG_04019) Elisa Kit
  • lipoic acid synthetase (TERG_02451) Elisa Kit
  • lipoic acid synthetase (Tsp_01534) Elisa Kit
  • lipoic acid synthetase (LIAS) Elisa Kit
  • lipoic acid synthetase (Lias) Elisa Kit
  • lipoic acid synthetase (lias) Elisa Kit
  • LOC100279807 (umc2251) Elisa Kit
  • 7a5ex Elisa Kit
  • 2900022L22Rik Elisa Kit
  • 4933425M12Rik Elisa Kit
  • C77512 Elisa Kit
  • LAS Elisa Kit
  • Lip-syn Elisa Kit
  • LIP1 Elisa Kit
  • LS Elisa Kit
  • mLip1 Elisa Kit
  • PDHLD Elisa Kit
  • zgc:66080 Elisa Kit

Protein level used designations for LIAS

lipoic acid synthetase , lip-syn , lipoate synthase , lipoyl synthase, mitochondrial , LS , lipoic acid synthase , Lipoate synthase , Lipoic acid synthase , PCO124891 , PCO124891_ov , p-umc2251

GENE ID SPECIES
5571879 Aedes aegypti
7452159 Thalassiosira pseudonana CCMP1335
7453454 Thalassiosira pseudonana CCMP1335
8437299 Uncinocarpus reesii 1704
9941423 Loa loa
10379120 Trichophyton rubrum CBS 118892
10911601 Trichinella spiralis
11019 Homo sapiens
79464 Mus musculus
305348 Rattus norvegicus
393528 Danio rerio
443960 Xenopus laevis
479108 Canis lupus familiaris
530865 Bos taurus
100279807 Zea mays
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