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Human Polyclonal PFDN6 Primary Antibody for WB - ABIN389346
Vainberg, Lewis, Rommelaere, Ampe, Vandekerckhove, Klein, Cowan: Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. in Cell 1998
Show all 4 Pubmed References
The localization of the HKE2 gene to the class II region, its cytoplasmic expression and putative protein-binding domain suggest that HKE2 may function in adaptive immunity and cancer.
Is part of an RNA polymerase II-associated complex with possible chaperone activity.
PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999
prefoldin subunit 6
, prefoldin subunit 6 a
, Prefoldin subunit 6
, protein Ke2
, HLA class II region expressed gene KE2
, KE2 protein
, prefoldin subunit 6 b
, MHC class II region expressed gene KE2
, prefoldin 6