Browse our Placenta Growth Factor Proteins (PGF)

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Placenta Growth Factor Proteins (PGF)
On are 53 Placenta Growth Factor (PGF) Proteins from 15 different suppliers available. Additionally we are shipping Placenta Growth Factor Antibodies (317) and Placenta Growth Factor Kits (74) and many more products for this protein. A total of 452 Placenta Growth Factor products are currently listed.
AI854365, D12S1900, PGFL, PIGF, PlGF, PlGF-2, SHGC-10760
list all proteins Gene Name GeneID UniProt
PGF 5228 P49763
PGF 18654 P49764
PGF 94203 Q63434

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Placenta Growth Factor Proteins (PGF) by Origin

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Top referenced Placenta Growth Factor Proteins

  1. Human PGF Protein expressed in Wheat germ - ABIN1314804 : Kondo, Yamato, Takagi, Namiki, Okano: The regulation of epithelial cell proliferation and growth by IL-1 receptor antagonist. in Biomaterials 2012 (PubMed)

  2. Human PGF Protein expressed in Human Cells - ABIN2002492 : Luttun, Tjwa, Carmeliet: Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders. in Annals of the New York Academy of Sciences 2003 (PubMed)

  3. Human PGF Protein expressed in Escherichia coli (E. coli) - ABIN413725 : Ding, Huang, Song, Gao, Yuan, Wang, Cai, Fu, Luo: NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

  4. Rat (Rattus) PGF Protein expressed in Escherichia coli (E. coli) - ABIN2126310 : Zhang, Zhao, Yuan, Wu, Jiang, Luo, Zhao: Knockdown of placental growth factor (PLGF) mitigates hyperoxia-induced acute lung injury in neonatal rats: Suppressive effects on NFκB signaling pathway. in International immunopharmacology 2016 (PubMed)

More Proteins for Placenta Growth Factor Interaction Partners

Human Placenta Growth Factor (PGF) interaction partners

  1. Results show that both FLT1 (show FLT1 Proteins) and PGF are overexpressed in the circulating tumor cells (CTCs) of patients with breast cancer. Also, a functional interaction of sFlt1 (show FLT1 Proteins) and PGF was found, suggesting that their overexpression in tumor cells inhibits CTCs entering the peripheral blood.

  2. Identify a novel cis (show CISH Proteins)-acting sequence (-369 to -320) at the placental growth factor promoter, which was critical for mediating the basal and DLX3 (show DLX3 Proteins)/GCM1 (show GCM1 Proteins)-dependent PGF promoter activities.

  3. Low PlGF identifies small fetuses with significant underlying placental pathology and is a promising tool for antenatal discrimination of fetal growth retardation from fetuses who are constitutionally-small.

  4. Serum and urinary sFlt-1 and sFlt-1/PLGF ratios in severe preeclampsia patients were significantly higher than those in the mild preeclampsia group, and mild preeclampsia patients were significantly higher than controls. The serum and urinary PLGF levels in severe preeclampsia patients were significantly lower than mild preeclampsia patients, and mild preeclampsia patients had significantly lower PLGF levels than controls

  5. ROS (show ROS1 Proteins) activation of the MAPK (ERK (show MAPK1 Proteins)-1 (show MAPK3 Proteins)/2)/Egr-1 (show EGR1 Proteins) pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF production. Antioxidants could partly abolish these effects.

  6. Both the TNF-alpha (show TNF Proteins)/IL-10 (show IL10 Proteins) and sFlt-1/PlGF ratios were higher in placental homogenate of early-onset Preeclampsia (PE) than late-onset PE and control groups. The more severe lesions and the imbalance between TNF-alpha (show TNF Proteins)/IL-10 (show IL10 Proteins) and PlGF/sFlt-1 in placentas from early-onset PE allows differentiation of early and late-onset PE and suggests higher placental impairment in early-onset PE

  7. PlGF is abundant in the human endometrium, and secreted into the uterine lumen where it mediates functional changes in cellular adhesion with important roles in implantation

  8. The preeclampsia group had lower placental growth factor from 18 weeks compared to controls.

  9. A strong, novel prospective association was identified between lower concentrations of soluble Fms (show CSF1R Proteins)-like kinase 1 and placental growth factor measured in early pregnancy and spontaneous abortion.

  10. Women with preeclampsia had lower plasma concentrations of placental growth factor. The uteroplacental arteriovenous differences of placental growth factor were significant in both preeclampsia and control groups.

Mouse (Murine) Placenta Growth Factor (PGF) interaction partners

  1. PGF (show PTGFR Proteins) deficiency is associated with impaired cerebral vascular development in mice.

  2. PlGF inhibition attenuates PERK (show EIF2AK3 Proteins) activation, likely by tempering hypoxia in HCC (show FAM126A Proteins) via vessel normalisation. The UPR is able to regulate PlGF expression, suggesting the existence of a feedback mechanism for hypoxia-mediated UPR

  3. Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13 (show IL13 Proteins).

  4. Data indicate that placental growth factor (PlGF) is needed in the spleen to allow the activation of T cells and blood pressure raising.

  5. Placental growth factor promotes differentiation of bone marrow-derived macrophages and enhanced vascular endothelial cell proliferation.

  6. PLGF in LC cells induced macrophage polarization in vivo, and significantly promoted the growth of LC.

  7. PLGF is upregulated in vascular cells in response to fluid shear stress.

  8. Data suggests that PLGF may target islet endothelia to release growth factors activating PI3k signalling in beta cells to increase their proliferation. In Pre-Eclampsia, PLGF reduction impairs these processes resulting in gestational diabetes mellitus.

  9. The neutrophil elastase (show ELANE Proteins)-PlGF-JNK (show MAPK8 Proteins)/PKCdelta (show PKCd Proteins) pathway contributes to the pathogenesis of lung epithelial cell apoptosis and emphysema.

  10. E2F1 (show E2F1 Proteins) limits cardiac neovascularization and functional recovery after myocardial infarction by suppressing VEGF (show VEGFA Proteins) and PlGF up-regulation through p53 (show TP53 Proteins)-dependent and -independent mechanisms, respectively.

Cow (Bovine) Placenta Growth Factor (PGF) interaction partners

  1. Study reports polymorphisms in the bovine PGF gene significantly associated with the maternal effect on stillbirth and calving ease in animals under selection.

  2. placenta growth factor expression is regulated by both VEGF (show VEGFA Proteins) and hyperglycaemia via VEGFR-2 (show KDR Proteins)

Placenta Growth Factor (PGF) Protein Profile

Protein Summary

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Placenta Growth Factor (PGF)

  • placental growth factor, vascular endothelial growth factor-related protein (LOC100339515)
  • placenta growth factor (PLGF)
  • placenta growth factor-like (LOC100855780)
  • placental growth factor (PGF)
  • placental growth factor (Pgf)
  • placental growth factor (PLGF)
  • AI854365 protein
  • D12S1900 protein
  • PGFL protein
  • PIGF protein
  • PlGF protein
  • PlGF-2 protein
  • SHGC-10760 protein

Protein level used designations for Placenta Growth Factor Proteins (PGF)

placental growth factor, vascular endothelial growth factor-related protein , placenta growth factor , placenta growth factor-like

100339515 Oryctolagus cuniculus
541591 Sus scrofa
100855780 Canis lupus familiaris
5228 Homo sapiens
18654 Mus musculus
94203 Rattus norvegicus
280894 Bos taurus
100156404 Sus scrofa
100734450 Cavia porcellus
771832 Gallus gallus
443245 Ovis aries
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