anti-Human SHC2 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended SHC2 Antibody (supplied by: Log in to see )

Antigen
SHC (Src Homology 2 Domain Containing) Transforming Protein 2 (SHC2) Antibodies
  • SCK
  • SHCB
  • SLI
  • 6720466E06
  • ShcB
  • Sli
  • SHC (Src homology 2 domain containing) transforming protein 2
  • SHC2
  • Shc2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
35
24
23
4
1
Host
Rabbit
30
4
4
Clonality
Polyclonal
Conjugate
This SHC2 antibody is conjugated to Alexa Fluor 350
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
25
12
9
4
4
3
3
1
1
Options
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Catalog No. ABIN1395417
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1395418 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1395419 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1395420 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1395422 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1413309 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN1413310 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1413311 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1413312 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN2806350 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN1386708 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN5010493 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal
1 ABIN5010494 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal

General

Antigen SHC (Src Homology 2 Domain Containing) Transforming Protein 2 (SHC2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(35), (24), (23), (4), (1)
Host Rabbit
(30), (4), (4)
Clonality
Polyclonal
Conjugate This SHC2 antibody is conjugated to Alexa Fluor 350
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(25), (12), (9), (4), (4), (3), (3), (1), (1)
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Product Details anti-SHC2 Antibody

Target Details SHC2 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SHC2/Sck
Isotype IgG

Target Details SHC2

Product Details anti-SHC2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Shc2/Sck (SHC2 Antibody Abstract)
Background

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events (1). Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain (2,3). Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary (4,5). In vascular endothelial cells, Sck participates in VEGF-induced signal transduction (6). Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation (7,8).

Synonyms: Protein Sck, SCK, SH2 domain protein C2, SHC transforming protein 2, SHCB, Src homology 2 domain containing transforming protein C2, SHC2_HUMAN.

Pathways RTK Signaling, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals

Application Details

Product Details anti-SHC2 Antibody Target Details SHC2 Handling Images back to top
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-SHC2 Antibody Target Details SHC2 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months