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anti-Rat (Rattus) Adenomatous Polyposis Coli antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Adenomatous Polyposis Coli Antibody (supplied by: Log in to see )

Antigen
Adenomatous Polyposis Coli (APC) Antibodies
  • AI047805
  • APC1
  • AU020952
  • AW124434
  • BTPS2
  • CC1
  • dp2
  • DP2
  • DP2.5
  • dp2.5
  • DP3
  • dp3
  • fap
  • fpc
  • GS
  • mAPC
  • Min
  • PPP1R46
  • RATAPC
  • xapc
Reactivity
Human, Mouse (Murine), Rat (Rattus)
114
72
41
6
4
2
2
1
1
Host
Rabbit
123
15
14
2
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
4
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
93
61
41
29
26
22
13
9
5
4
2
1
1
Supplier
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Catalog No. ABIN271993
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089487544 ABIN265313 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089487544 ABIN373037 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.00089487544 ABIN372972 IHC (p) IP Rabbit C-Term Log in to see Polyclonal
0.00089487544 ABIN702550 IF (p) IHC (p) Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089487544 ABIN1731843 IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089487544 ABIN2852374 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089487544 ABIN1858036 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 2634-2842 Log in to see Polyclonal
0.00089487544 ABIN702552 IHC (p) Biotin Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089487544 ABIN702559 IHC (p) HRP Rabbit IgG AA 2790-2843 Log in to see Polyclonal
0.00089487544 ABIN407592 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-Adenomatous Polyposis Coli Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 61 Antibodies 52 Antibodies 23 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 14 Antibodies 5 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 44 Antibodies 13 Antibodies 15 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies 2 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 11 Antibodies

General

Antigen Adenomatous Polyposis Coli (APC) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(114), (72), (41), (6), (4), (2), (2), (1), (1)
Host Rabbit
(123), (15), (14), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(7), (7), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(93), (61), (41), (29), (26), (22), (13), (9), (5), (4), (2), (1), (1)
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Product details

Target details Application Details Handling Images
Specificity This antibody detects endogenous levels of APC protein. (region surrounding Lys2050)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target details

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Antigen
Alternative Name APC / DP2.5 (APC Antibody Abstract)
Background Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.Synonyms: Adenomatous polyposis coli protein, Deleted in polyposis 2.5
Molecular Weight approx. 310 kDa
Gene ID 324
NCBI Accession NP_000029
UniProt P25054
Research Area Coagulation
Pathways WNT Signaling

Application Details

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Application Notes ELISA: 1: 1000approx. 1: 5000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

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Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

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Supplier Images
 image for anti-Adenomatous Polyposis Coli (APC) antibody (ABIN271993) anti-Adenomatous Polyposis Coli (APC) antibody