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Browse our AXIN1 Proteins (AXIN1)

Full name:
Axin 1 Proteins (AXIN1)
On www.antibodies-online.com are 5 Axin 1 (AXIN1) Proteins from 4 different suppliers available. Additionally we are shipping AXIN1 Antibodies (136) and AXIN1 Kits (14) and many more products for this protein. A total of 164 AXIN1 products are currently listed.
Synonyms:
AI316800, Axin, AXIN1, AXIN1-RGS, Fu, fused, Kb, Ki, kinky, knobbly, LOC100226467, PPP1R49, wu:fi22e03, wu:fj14c08, wu:fk11b03, xAxin, zgc:109872
list all proteins Gene Name GeneID UniProt
AXIN1 8312 O15169
AXIN1 12005 O35625
Rat AXIN1 AXIN1 79257 O70239

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AXIN1 Proteins (AXIN1) by Origin

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More Proteins for AXIN1 Interaction Partners

Xenopus laevis Axin 1 (AXIN1) interaction partners

  1. analysis of differential role of Axin RGS (show PITX2 Proteins) domain function in Wnt (show WNT2 Proteins) signaling during anteroposterior patterning and maternal axis formation

  2. APC (show APC Proteins) and Axin are involved in the Wnt (show WNT2 Proteins) pathway

  3. Axin binds directly to the export factor CRM1 in the presence of RanGTP

Human Axin 1 (AXIN1) interaction partners

  1. Cancer point mutations in the scaffold protein (show HOMER1 Proteins) Axin derail Wnt (show WNT2 Proteins) signaling and promote tumor growth in vivo through a gain-of-function mechanism.

  2. The pool of ADP-ribosylated Axin, which is degraded under basal conditions, increases immediately following Wnt (show WNT2 Proteins) stimulation in both Drosophila and human cells.

  3. Data show that 5-hydroxytryptamine receptor (5-HT1DR) played an important role in cell invasion via Axin1/beta-catenin (show CTNNB1 Proteins)/matrix metalloproteinase 7 (MMP-7 (show MMP7 Proteins)) pathway.

  4. GSK3 acts through APC motifs R2 and B to regulate APC:Axin interactions, promoting high-throughput of betacatenin to destruction.

  5. We have offered primary evidence that the T allele and T/T genotype of rs370681 polymorphisms and C/T genotype of rs1805105 polymorphisms in AXIN1 gene are more frequent in patients with cryptorchidism.

  6. Higher expression of AXIN1 protein in IUGR placentae indicates a role of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway in pathology of placental development.

  7. This study study showed that HMGA2 was able to elicit EMT (show ITK Proteins) and regulate several genes which are closely related to the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway by directly binding to their promoter.

  8. suggest a novel mechanism of Wnt (show WNT2 Proteins) signaling through the dissociation of the beta-catenin (show CTNNB1 Proteins) destruction complex by Axin1 Thr160 modification

  9. In adenomatous polyposis coli, beta-catenin phosphorylation involves Axin and the 20 amino acids of APC or APCL.

  10. Which destabilize beta-catenin (show CTNNB1 Proteins) through stabilizing Axin.

Mouse (Murine) Axin 1 (AXIN1) interaction partners

  1. Axin1 promotes dendritic spine stabilization through Cdc42 (show CDC42 Proteins)-dependent cytoskeletal reorganization.

  2. Axin1 and Axin2 (show AXIN2 Proteins) do not have equivalent functions in satellite cells, but are both involved in repression of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling to maintain proliferation and contribute to controlling timely myogenic differentiation.

  3. Study reports that NRF2 (show NFE2L2 Proteins) participates in the formation of a protein complex with Axin1/GSK-3/beta-TrCP (show BTRC Proteins) that is disrupted by WNT-3A (show WNT3A Proteins), a prototypic canonical WNT (show WNT2 Proteins) ligand, and leads to upregulation of the NRF2 (show NFE2L2 Proteins) transcriptional signature.

  4. Smurf1 (show SMURF1 Proteins)-mediated Lys29-linked nonproteolytic polyubiquitination of axin1 negatively regulates Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling.

  5. This study demonistrated that Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex in mice.

  6. results suggestg HSV-1 replication enhancement might be mediated by the axin RGS (show PITX2 Proteins) domain.

  7. an asymmetrical distribution pattern for Axin1 transcripts in 2-cell embryos.

  8. Conditional disruption of Axin1 leads to development of liver tumors in mice.

  9. The Axin/TNKS2 (show TNKS2 Proteins)/KIF3A (show KIF3A Proteins) complex is critical for GLUT4 (show SLC2A4 Proteins) translocation in response to insulin (show INS Proteins).

  10. Phosphorylation of axin-1 by glycogen synthase kinase-3beta accelerates association of axin-1 with beta-catenin (show CTNNB1 Proteins) in dorsal root ganglion growth cones.

Zebrafish Axin 1 (AXIN1) interaction partners

  1. beta-catenin1 cannot revert the ich (show ACE Proteins) phenotype because it may be under the control of a GSK3beta-independent mechanism that required Axin's RGS (show PITX2 Proteins) domain function.

  2. analysis of differential role of Axin RGS (show PITX2 Proteins) domain function in Wnt (show WNT2 Proteins) signaling during anteroposterior patterning and maternal axis formation

  3. Wnt (show WNT2 Proteins)/Axin/beta-catenin (show CTNNB1 Proteins) pathway has a role in ventral CNS development

  4. Overactivation of Wnt (show WNT2 Proteins)/Axin1/beta-catenin (show CTNNB1 Proteins) signaling during late gastrulation leads to bilateral epithalamic expression of Nodal pathway genes independently of lateral plate mesoderm Nodal signaling.

  5. A dorsalization pathway that is exerted by Axin/JNK (show MAPK8 Proteins) signaling and its inhibitor Aida (show AIDA Proteins) during vertebrate embryogenesis, is defined.

  6. Dab2 (show DAB2 Proteins) stabilizes Axin and attenuates Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling by preventing PP1 (show PPYR1 Proteins) from binding Axin

AXIN1 Protein Profile

Protein Summary

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with AXIN1

  • axin 1 (AXIN1)
  • axin 1 (axin1)
  • axin 1 (LOC100226467)
  • axin (axin1)
  • axin 1 (Axin1)
  • AI316800 protein
  • Axin protein
  • AXIN1 protein
  • AXIN1-RGS protein
  • Fu protein
  • fused protein
  • Kb protein
  • Ki protein
  • kinky protein
  • knobbly protein
  • LOC100226467 protein
  • PPP1R49 protein
  • wu:fi22e03 protein
  • wu:fj14c08 protein
  • wu:fk11b03 protein
  • xAxin protein
  • zgc:109872 protein

Protein level used designations for Axin 1 Proteins (AXIN1)

axin 1 , axin 1, isoform 1 , axin-1-like , axin-1 , xAxin , axis inhibition protein 1 , axis inhibitor 1 , fused, mouse, homolog of , protein phosphatase 1, regulatory subunit 49 , protein Fused , GSK-3beta interacting protein rAxin , rAxin , masterblind , mbl

GENE ID SPECIES
453789 Pan troglodytes
734298 Xenopus laevis
100137557 Papio anubis
100226467 Taeniopygia guttata
100392475 Callithrix jacchus
100424087 Macaca mulatta
398097 Xenopus laevis
100065116 Equus caballus
8312 Homo sapiens
490099 Canis lupus familiaris
504357 Bos taurus
12005 Mus musculus
79257 Rattus norvegicus
100718536 Cavia porcellus
395786 Gallus gallus
57931 Danio rerio
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