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Axin Proteins

(Axin 1 (AXIN1))
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010].
Axin Protein (AA 540-768) (His tag) Axin Protein (AA 540-768) (His tag) Axin Protein (AA 540-768) (His tag) (ABIN7121954)

AXIN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

Axin Protein (AA 643-740) (GST tag) Axin Protein (AA 643-740) (GST tag) Axin Protein (AA 643-740) (GST tag) (ABIN1346237)

AXIN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Axin Protein (AA 1-862) (His tag) Axin Protein (AA 1-862) (His tag) Axin Protein (AA 1-862) (His tag) (ABIN3089641)

Crystallography grade AXIN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Axin Proteins by Grade

Find Axin Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Axin Proteins by Origin

Find Axin Proteins for a variety of species such as anti-Human Axin, anti-Mouse Axin, anti-Rat Axin. The species listed below are among those available. Click on a link to go to the corresponding products.

Axin Proteins by Source

Here you will find Axin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Axin Proteins by Protein Type

Here you can find Axin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Axin Proteins by Application

Find Axin Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Axin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121954
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346237
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089641
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131624
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2715088
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405157
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406062
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405900
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008424
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Axin Proteins

Cha, Cho, Lee, Lee, Jeong, Moon, Yun, Yang, Choi, Yoon, Kim, Kim, Kaduwal, Lee, Min, Kim, Han, Choi: "Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation." in: Nature chemical biology, Vol. 12, Issue 8, pp. 593-600, (2016) (PubMed).

Aliases for Axin Proteins

axin 1 (AXIN1) Proteins
axin 1 S homeolog (axin1.S) Proteins
axin 1 L homeolog (axin1.L) Proteins
axin 1 (Axin1) Proteins
axin 1 (axin1) Proteins
AI316800 Proteins
axin Proteins
AXIN Proteins
Axin Proteins
AXIN1 Proteins
AXIN1-RGS Proteins
Fu Proteins
fused Proteins
Kb Proteins
Ki Proteins
kinky Proteins
knobbly Proteins
LOC100226467 Proteins
PPP1R49 Proteins
wu:fi22e03 Proteins
wu:fj14c08 Proteins
wu:fk11b03 Proteins
xAxin Proteins
zgc:109872 Proteins
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